Prenatal phthalate exposure and birth size: a systematic review and meta-analysis.
Int J Environ Health Res
; : 1-17, 2023 Nov 18.
Article
en En
| MEDLINE
| ID: mdl-37979196
ABSTRACT
Phthalates are common endocrine disruptors. The placental barrier can be crossed by phthalates and may have a negative impact on the health of the fetus. However, the association between prenatal exposure to phthalates and birth size is still debatable. Here, we performed this meta-analysis to assess the relationship between prenatal phthalates exposure and birth size. Eighteen studies were finally included by searching PubMed, Embase, Scopus, Ovid, and Web of Science databases and standardized regression coefficients and standard errors were used to pool effect size. Our results showed that prenatal exposure to MMP (=-0.04, 95%CI -0.08, -0.01) and MEP (=-0.01, 95%CI -0.01, -0.002) was significantly associated with birth weight. However, no significant associations were identified for phthalate exposure with birth length, head circumference and chest circumference. Because the limiting of studies, more high-quality case-control studies or cohort studies are urgently needed to draw the best conclusions.
Texto completo:
1
Banco de datos:
MEDLINE
Tipo de estudio:
Systematic_reviews
Idioma:
En
Revista:
Int J Environ Health Res
Asunto de la revista:
SAUDE AMBIENTAL
Año:
2023
Tipo del documento:
Article
País de afiliación:
China