Detection of parechovirus A in respiratory, gastrointestinal, and neurological clinical samples of pediatric patients from Panama (2014-2015).
Virol J
; 20(1): 302, 2023 12 19.
Article
en En
| MEDLINE
| ID: mdl-38115118
ABSTRACT
Parechovirus A (PeV-A, Parechovirus, Picornaviridae) are human pathogens associated with mild to severe gastrointestinal and respiratory diseases in young children. While several studies have investigated the association of PeV-A with human disease, little is known about its epidemiology or detection in Latin America. Between the years 2014 and 2015, a total of 200 samples were collected from Panamanian pediatric patients aged < 16 years old exhibiting symptoms associated with respiratory (n = 64), gastrointestinal (n = 68), or neurological (n = 68) diseases. These samples were gathered from patients who had previously received negative diagnoses for the main respiratory viruses, rotavirus, and neurological viruses like herpes virus, enterovirus, and cytomegalovirus. The presence of PeV-A was analyzed by real time RT-PCR.Eight positive PeV-A infections (4.0%, 95% CI 1.7 to 7.7) were detected two in respiratory samples (3.0%, 95% CI 0.3 to 10.8), five in gastrointestinal samples (7.3%, 95% CI 2.4 to 16.3), and one in cerebrospinal fluid (1.5%, 95% CI 1.4 to 7.9). The study provides evidence of PeV-A circulation in Panama and the data collectively, remarked on the importance of considering PeV-A in the Panamanian pediatric diagnostic landscape, especially when conventional testing for more common viruses yields negative results.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Picornaviridae
/
Enterovirus
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Infecciones por Picornaviridae
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Parechovirus
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Infecciones por Enterovirus
Límite:
Adolescent
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Child
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Child, preschool
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Humans
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Infant
País/Región como asunto:
America central
/
Panama
Idioma:
En
Revista:
Virol J
Asunto de la revista:
VIROLOGIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos