Lyophilized (freeze-dried) human milk for preterm infants: a scoping review.
J Perinatol
; 44(5): 612-627, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38225373
ABSTRACT
Freeze-drying (FD), or lyophilization, is commonly used to preserve foods. FD offers potential to create a human milk-derived human milk fortifier, and an alternative to freeze-storing human milk. However, processing human milk is known to affect its components. This scoping review explores the effect of FD on the; macronutrient, micronutrient, vitamin, bioactive components, microbes and anti-microbial factors in human milk, and studies where lyophilized human milk has been given to newborn infants. 48 articles were identified after full text review. FD human milk reduces the fat globule size and as well as the quantity of enzymes, vitamin C and immunoglobulin. Common serum electrolyte disturbances have been reported when preterm infants' are fed FD human milk however it appears a promising method to avoid exposure of preterm infants' to cows' milk. Due to limited data, further studies exploring the safety and efficacy of FD human milk in preterm infants are needed.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Recien Nacido Prematuro
/
Liofilización
/
Leche Humana
Tipo de estudio:
Prognostic_studies
/
Systematic_reviews
Límite:
Humans
/
Newborn
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Canadá