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Pharmacological interventions in human aging.
Petr, Michael Angelo; Matiyevskaya, Frida; Osborne, Brenna; Berglind, Magnus; Reves, Simon; Zhang, Bin; Ezra, Michael Ben; Carmona-Marin, Lina Maria; Syadzha, Muhammad Farraz; Mediavilla, Marta Cortés; Keijzers, Guido; Bakula, Daniela; Mkrtchyan, Garik V; Scheibye-Knudsen, Morten.
Afiliación
  • Petr MA; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Matiyevskaya F; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Osborne B; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Berglind M; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Reves S; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Zhang B; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Ezra MB; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Carmona-Marin LM; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Syadzha MF; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Mediavilla MC; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Keijzers G; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Bakula D; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Mkrtchyan GV; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark.
  • Scheibye-Knudsen M; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen 2200, Denmark. Electronic address: mscheibye@sund.ku.dk.
Ageing Res Rev ; 95: 102213, 2024 03.
Article en En | MEDLINE | ID: mdl-38309591
ABSTRACT
Pharmacological interventions are emerging as potential avenues of alleviating age-related disease. However, the knowledge of ongoing clinical trials as they relate to aging and pharmacological interventions is dispersed across a variety of mediums. In this review we summarize 136 age-related clinical trials that have been completed or are ongoing. Furthermore, we establish a database that describe the trials (AgingDB, www.agingdb.com) keeping track of the previous and ongoing clinical trials, alongside their outcomes. The aim of this review and database is to give people the ability to easily query for their trial of interest and stay up to date on the latest results. In sum, herein we give an overview of the current pharmacological strategies that have been applied to target human aging.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento Límite: Humans Idioma: En Revista: Ageing Res Rev Asunto de la revista: GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento Límite: Humans Idioma: En Revista: Ageing Res Rev Asunto de la revista: GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca