Use of the Community-Derived Open-Source Automated Insulin Delivery Loop System in Type 2 Diabetes.
Diabetes Technol Ther
; 26(7): 494-497, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38386434
ABSTRACT
Background:
No published data are available on the use of the community-derived open-source Loop hybrid closed-loop controller ("Loop") by individuals with type 2 diabetes (T2D).Methods:
Through social media postings, we invited individuals with T2D currently using the Loop system to join an observational study. Thirteen responded of whom seven were eligible for the study, were using the Loop algorithm, and provided data.Results:
Mean (±standard deviation) age was 61 ± 13 years, and mean body mass index was 31 ± 5 kg/m2. All but one participant were using noninsulin glucose-lowering medications. Self-reported mean hemoglobin A1c decreased from 7.3% ± 1.1% before starting Loop to 6.0% ± 0.5% on Loop. Time in range 70-180 mg/dL increased from 84% to 93%. The amount of time in hypoglycemia was extremely low before and with Loop (time <54 mg/dL was 0.04% ± 0.06% vs. 0.09% ± 0.07%, respectively). No severe hypoglycemia or diabetic ketoacidosis events were reported while using Loop.Conclusion:
These data, though limited, suggest that the Loop system is likely to be effective when used by individuals with T2D and should be evaluated in large-scale studies. Clinical Trial Registration numbers NCT05951569.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Glucemia
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Sistemas de Infusión de Insulina
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Diabetes Mellitus Tipo 2
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Hipoglucemiantes
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Insulina
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Diabetes Technol Ther
Asunto de la revista:
ENDOCRINOLOGIA
/
TERAPEUTICA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos