Obstructive sleep apnoea in obesity: A review.
Clin Obes
; 14(3): e12651, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38419261
ABSTRACT
Obstructive sleep apnea is a common comorbidity that occurs in individuals with obesity. It classically manifests with excessive daytime sleepiness, resulting in reduced quality of life, workplace productivity, and an increased risk of motor vehicle accidents. Weight gain plays an important role in its pathogenesis through worsening upper airway collapsibility, and current treatment options are targeted towards mechanically overcoming upper airway obstruction and weight loss. Continuous positive airway pressure therapy remains the most widely prescribed treatment for obstructive sleep apnea but poor tolerance is a common barrier to effective treatment. Sustainable weight loss is an important treatment option but can be difficult to achieve without bariatric surgery. The recent advances in incretin-based pharmacotherapies represent a promising avenue not only in achieving long-term weight loss but also in treating obstructive sleep apnoea and alleviating the burden of its symptoms and comorbidities.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Apnea Obstructiva del Sueño
/
Presión de las Vías Aéreas Positiva Contínua
/
Obesidad
Límite:
Humans
Idioma:
En
Revista:
Clin Obes
Año:
2024
Tipo del documento:
Article
País de afiliación:
Australia