PET/CT and PET/MR in Soft Tissue Sarcoma: An Update.
Semin Nucl Med
; 54(3): 313-331, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38423851
ABSTRACT
Soft tissue sarcomas account for 6%-8% of pediatric cancers. The rhabdomyosarcoma family is the most frequent soft tissue sarcoma in this age group accounting for 3% of pediatric cancers. Rhabdomyosarcomas are high-grade tumors with a high propensity to metastasize. The risk-adapted, multimodal therapeutic approach for rhabdomyosarcomas incorporates a combination of surgery, radiotherapy, and multi-agent cytotoxic chemotherapy. Soft tissue sarcomas other than rhabdomyosarcoma account for 3%-4% of pediatric cancers. The nonrhabdomyosarcoma soft tissue sarcomas include both low-grade and high-grade tumors. While surgery is the mainstay of therapy in most non-rhabdomyosarcoma soft tissue sarcomas, many cases require a multimodal therapeutic approach including radiotherapy and chemotherapy. In North America, most pediatric patients with soft tissue sarcomas are treated in Children's Oncology Group clinical trials. In this article, we will primarily focus on the staging, risk stratification, imaging recommendations, and interpretations in accordance with the Children's Oncology Group trials. We will review the results and recommendations of International Soft Tissue Sarcoma Database Consortium and European trials in relevant sections where they provide complementary guidelines.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sarcoma
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Imagen por Resonancia Magnética
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Tomografía Computarizada por Tomografía de Emisión de Positrones
Límite:
Humans
Idioma:
En
Revista:
Semin Nucl Med
Año:
2024
Tipo del documento:
Article
País de afiliación:
Túnez