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AAV mediated genome engineering with a bypass coagulation factor alleviates the bleeding phenotype in a murine model of hemophilia B.
Sarangi, Pratiksha; Kumar, Narendra; Sambasivan, Ramkumar; Ramalingam, Sivaprakash; Amit, Sonal; Chandra, Dinesh; Jayandharan, Giridhara R.
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  • Sarangi P; Laurus Center for Gene Therapy, Department of Biological Sciences and Bioengineering and Mehta Family Centre for Engineering in Medicine and Gangwal School of Medical Sciences and Technology, Indian Institute of Technology Kanpur, UP, India.
  • Kumar N; Laurus Center for Gene Therapy, Department of Biological Sciences and Bioengineering and Mehta Family Centre for Engineering in Medicine and Gangwal School of Medical Sciences and Technology, Indian Institute of Technology Kanpur, UP, India.
  • Sambasivan R; Department of Biology, Indian Institute of Science Education and Research Tirupati, Andhra Pradesh, India.
  • Ramalingam S; CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
  • Amit S; Autonomous State Medical College, Kumbhi, Akbarpur, Kanpur, UP, India.
  • Chandra D; Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
  • Jayandharan GR; Laurus Center for Gene Therapy, Department of Biological Sciences and Bioengineering and Mehta Family Centre for Engineering in Medicine and Gangwal School of Medical Sciences and Technology, Indian Institute of Technology Kanpur, UP, India. Electronic address: jayrao@iitk.ac.in.
Thromb Res ; 238: 151-160, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38718473
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hemofilia B / Dependovirus / Modelos Animales de Enfermedad Límite: Animals / Humans Idioma: En Revista: Thromb Res Año: 2024 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hemofilia B / Dependovirus / Modelos Animales de Enfermedad Límite: Animals / Humans Idioma: En Revista: Thromb Res Año: 2024 Tipo del documento: Article País de afiliación: India