An expert discussion on the atypical hemolytic uremic syndrome nomenclature-identifying a road map to precision: a report of a National Kidney Foundation Working Group.
Kidney Int
; 106(3): 326-336, 2024 Sep.
Article
en En
| MEDLINE
| ID: mdl-39174192
ABSTRACT
The term atypical hemolytic uremic syndrome has been in use since the mid-1970s. It was initially used to describe the familial or sporadic form of hemolytic uremic syndrome as opposed to the epidemic, typical form of the disease. Over time, the atypical hemolytic uremic syndrome term has evolved into being used to refer to anything that is not Shiga toxin-associated hemolytic uremic syndrome. The term describes a heterogeneous group of diseases of disparate causes, a circumstance that makes defining disease-specific natural history and/or targeted treatment approaches challenging. A working group of specialty-specific experts in the thrombotic microangiopathies was convened to review the validity of this broad term in an era of swiftly advancing science and targeted therapeutics. A Delphi approach was used to define and interrogate some of the key issues related to the atypical hemolytic uremic syndrome nomenclature.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Técnica Delphi
/
Síndrome Hemolítico Urémico Atípico
/
Terminología como Asunto
Límite:
Humans
Idioma:
En
Revista:
Kidney Int
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos