Myopathy and primary aldosteronism: electronmicroscopic study.
Neurology
; 29(10): 1348-53, 1979 Oct.
Article
en En
| MEDLINE
| ID: mdl-573378
ABSTRACT
We studied two patients with myopathy and primary aldosteronism. Necrosis and vacuolation of muscle fibers were found on light microscopy. Ultrastructurally, the necrotic areas were characterized by dissolution of myofilaments with degenerative vacuoles. In muscle fibers that did not show necrosis, there were membrane-bound vacuoles, dilation of the sarcoplasmic reticulum, widening of the T-system, and a "honeycomb" appearance of T-tubules. These ultrastructural features suggest that the necrosis of muscle fibers may originate from membrane vulnerability of the sarcoplasmic reticulum and the T-system.
Buscar en Google
Banco de datos:
MEDLINE
Asunto principal:
Hiperaldosteronismo
/
Músculos
/
Enfermedades Musculares
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neurology
Año:
1979
Tipo del documento:
Article