Antinuclear antibody-negative systemic lupus erythematosus-how common?
J Clin Pathol
; 35(10): 1118-21, 1982 Oct.
Article
en En
| MEDLINE
| ID: mdl-6982285
ABSTRACT
A review of five years' DNA-binding antibody results in a routine service laboratory revealed 38 patients who had high DNA-binding capacity (DNA-bc) but no antinuclear antibodies (ANA). On retrospective case note analysis, 22 patients (58%) were thought to have systemic lupus erythematosus (SLE), although only six (16%) fulfilled the preliminary classification criteria of the American Rheumatism Association (ARA). Our findings indicate that ANA-negative SLE is commoner than generally realised and lead us to recommended the measurement of DNA-bc in every case where clinically appropriate.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Anticuerpos Antinucleares
/
Lupus Eritematoso Sistémico
Límite:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Clin Pathol
Año:
1982
Tipo del documento:
Article