Selective reconstitution of CD8+ cytotoxic T lymphocyte responses in immunodeficient bone marrow transplant recipients by the adoptive transfer of T cell clones.
Bone Marrow Transplant
; 14 Suppl 4: S78-84, 1994.
Article
en En
| MEDLINE
| ID: mdl-7728132
ABSTRACT
The adoptive transfer of T cells specific for antigens encoded by pathogens and tumors has been an effective treatment for infections and malignancies in animal models and is potentially applicable for infections occurring in immunodeficient bone marrow transplant recipients. This article reviews recent insights derived from studies of the immunobiology of human cytomegalovirus (CMV) infection in healthy and immunodeficient hosts and the development of adoptive immunotherapy as prophylaxis for CMV infection in recipients of allogeneic bone marrow transplants.
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Banco de datos:
MEDLINE
Asunto principal:
Linfocitos T Citotóxicos
/
Inmunoterapia Adoptiva
/
Trasplante de Médula Ósea
/
Infecciones por Citomegalovirus
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Bone Marrow Transplant
Asunto de la revista:
TRANSPLANTE
Año:
1994
Tipo del documento:
Article