The base excision repair pathway.
Trends Biochem Sci
; 20(10): 391-7, 1995 Oct.
Article
en En
| MEDLINE
| ID: mdl-8533150
ABSTRACT
The base excision repair pathway has evolved to protect cells from the deleterious effects of endogenous DNA damage induced by hydrolysis, reactive oxygen species and other intracellular metabolites that modify DNA base structure. However, base excision repair is also important to resist lesions produced by ionizing radiation and strong alkylating agents, which are similar to those induced by endogenous factors.
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Banco de datos:
MEDLINE
Asunto principal:
Reparación del ADN
/
Modelos Genéticos
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Trends Biochem Sci
Año:
1995
Tipo del documento:
Article
País de afiliación:
Francia