Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase.
Trends Cell Biol
; 8(10): 404-10, 1998 Oct.
Article
en En
| MEDLINE
| ID: mdl-9789329
ABSTRACT
A number of developmental processes that involve cell migration, growth or morphogenesis depend on extracellular signals. A molecule that provides such signals, known as hepatocyte growth factor/scatter factor (HGF/SF), has attracted considerable interest in recent years because of its distinct structure, mechanism of activation and important roles throughout embryogenesis. This review discusses the main features of HGF/SF and its receptor, the product of the c-met protooncogene, and their role in embryogenesis.
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Banco de datos:
MEDLINE
Asunto principal:
Factores de Transcripción
/
Factor de Crecimiento de Hepatocito
/
Proteínas Proto-Oncogénicas c-met
/
Desarrollo Embrionario y Fetal
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Cell Biol
Año:
1998
Tipo del documento:
Article
País de afiliación:
Alemania