ABSTRACT
To investigate coronavirus disease 2019 (COVID-19) in infants aged 0 to 3 months because there is currently a significant gap in the literature on the subject. A cross-sectional study was conducted with the involvement of 19 medical centers across Turkey and 570 infants. The majority of the patients were male (58.2%), and the three most common symptoms were fever (78.2%), cough (44.6%), and feeding intolerance (39.9%). The results showed that a small percentage of infants had positive blood (0.9%) or urine cultures (10.2%). Most infants presented with fever (78.2%). Children without underlying conditions (UCs) had mostly a complicated respiratory course and a normal chest radiography. Significant more positive urine culture rates were observed in infants with fever. A higher incidence of respiratory support requirements and abnormal chest findings were seen in infants with chronic conditions. These infants also had a longer hospital stay than those without chronic conditions. Conclusions: Our study discloses the clinical observations and accompanying bacterial infections found in infants aged under 3 months with COVID-19. These findings can shed light on COVID-19 in infancy for physicians because there is limited clinical evidence available. What is Known: ⢠COVID-19 in infants and older children has been seen more mildly than in adults. ⢠The most common symptoms of COVID-19 in infants are fever and cough, as in older children and adults. COVID-19 should be one of the differential diagnoses in infants with fever. What is New: ⢠Although most infants under three months had fever, the clinical course was uneventful and respiratory complications were rarely observed in healthy children. ⢠Infants with underlying conditions had more frequent respiratory support and abnormal chest radiography and stayed longer in the hospital.
Subject(s)
COVID-19 , Female , Humans , Infant , Infant, Newborn , Male , Chronic Disease , Cough/etiology , COVID-19/epidemiology , COVID-19/complications , Cross-Sectional Studies , Turkey/epidemiologyABSTRACT
Middle aortic syndrome is a severe form of aortic coarctation and mostly involves the thoracic and abdominal part of the aorta. Traditional surgical approach has some potential risks and repetitive operations. Percutaneous stent implantation is a feasible and safe method for the palliation of middle aortic syndrome in childhood. Herein, a child with middle aortic syndrome was presented who has been treated by transcatheter stent implantation.
Subject(s)
Aortic Coarctation , Stents , Humans , Child , Female , Aortic Coarctation/complications , Aortic Coarctation/diagnostic imaging , Aortic Coarctation/surgery , Aorta , Treatment OutcomeABSTRACT
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused a pandemic affecting many countries and millions of people. Physicians have encountered some rare and challenging cases related to SARS-CoV-2, a novel virus with still many unknowns. In order to share our experience of a such clinical picture, we present here a child with SARS-CoV-2-induced macrophage activation syndrome in the setting of juvenile idiopathic arthritis.