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1.

The PI3K p110Î´ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa, Stalin; Kushekhar, Kushi; Munthe, Ludvig A; Tjønnfjord, Geir E; Aandahl, Einar M; Okkenhaug, Klaus; Taskén, Kjetil.

J Immunol ; 202(5): 1397-1405, 2019 03 01.

Article in English | MEDLINE | ID: mdl-30692213

2.

T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses.

Skånland, Sigrid S; Moltu, Kristine; Berge, Torunn; Aandahl, Einar M; Taskén, Kjetil.

Biochem J ; 460(3): 399-410, 2014 Jun 15.

Article in English | MEDLINE | ID: mdl-24665965

3.

An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses.

Pettersen, Frank O; Torheim, Eirik A; Dahm, Anders E A; Aaberge, Ingeborg S; Lind, Andreas; Holm, Malin; Aandahl, Einar M; Sandset, Per M; Taskén, Kjetil; Kvale, Dag.

J Virol ; 85(13): 6557-66, 2011 Jul.

Article in English | MEDLINE | ID: mdl-21490090

4.

Protein kinase A antagonist inhibits ß-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice.

Brudvik, Kristoffer W; Paulsen, Jan E; Aandahl, Einar M; Roald, Borghild; Taskén, Kjetil.

Mol Cancer ; 10: 149, 2011 Dec 15.

Article in English | MEDLINE | ID: mdl-22168384

5.

A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties.

Ndhlovu, Lishomwa C; Leal, Fabio E; Eccles-James, Ijeoma G; Jha, Aashish R; Lanteri, Marion; Norris, Philip J; Barbour, Jason D; Wachter, Douglas J; Andersson, Jan; Taskén, Kjetil; Torheim, Eirik A; Aandahl, Einar M; Kallas, Esper G; Nixon, Douglas F.

Eur J Immunol ; 40(1): 134-41, 2010 Jan.

Article in English | MEDLINE | ID: mdl-19877008

6.

Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.

Torheim, Eirik A; Ndhlovu, Lishomwa C; Pettersen, Frank O; Larsen, Trine-Lise; Jha, Aashish R; Torgersen, Knut M; Kvale, Dag; Nixon, Douglas F; Taskén, Kjetil; Aandahl, Einar M.

Eur J Immunol ; 39(5): 1280-7, 2009 May.

Article in English | MEDLINE | ID: mdl-19384871

7.

LPS-activated monocytes suppress T-cell immune responses and induce FOXP3+ T cells through a COX-2-PGE2-dependent mechanism.

Bryn, Tone; Yaqub, Sheraz; Mahic, Milada; Henjum, Karen; Aandahl, Einar M; Taskén, Kjetil.

Int Immunol ; 20(2): 235-45, 2008 Feb.

Article in English | MEDLINE | ID: mdl-18156149

8.

Differentiation of naive CD4+ T cells into CD4+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation.

Mahic, Milada; Yaqub, Sheraz; Bryn, Tone; Henjum, Karen; Eide, Dag M; Torgersen, Knut M; Aandahl, Einar M; Taskén, Kjetil.

J Leukoc Biol ; 83(5): 1111-7, 2008 May.

Article in English | MEDLINE | ID: mdl-18270250

9.

Human regulatory T cells control TCR signaling and susceptibility to suppression in CD4+ T cells.

Chellappa, Stalin; Lieske, Nora V; Hagness, Morten; Line, Pål D; Taskén, Kjetil; Aandahl, Einar M.

J Leukoc Biol ; 100(1): 5-16, 2016 07.

Article in English | MEDLINE | ID: mdl-26715685

10.

Regulatory T cells that co-express RORÎ³t and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer.

Chellappa, Stalin; Hugenschmidt, Harald; Hagness, Morten; Line, Pål D; Labori, Knut J; Wiedswang, Gro; Taskén, Kjetil; Aandahl, Einar M.

Oncoimmunology ; 5(4): e1102828, 2016 Apr.

Article in English | MEDLINE | ID: mdl-27141387

11.

CD4+CD25+ regulatory T cells in HIV infection.

Nixon, Douglas F; Aandahl, Einar M; Michaëlsson, Jakob.

Microbes Infect ; 7(7-8): 1063-5, 2005 Jun.

Article in English | MEDLINE | ID: mdl-15893493

12.

New observations on CD8 cell responses.

Nixon, Douglas F; Aandahl, Einar M; Sandberg, Johan K.

AIDS ; 17 Suppl 4: S61-5, 2003.

Article in English | MEDLINE | ID: mdl-15080181

13.

Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy.

Johansson, C Christian; Bryn, Tone; Aandahl, Einar M; Areklett, Maria A; Aukrust, Pål; Taskén, Kjetil; Frøland, Stig S.

AIDS ; 18(6): 951-2, 2004 Apr 09.

Article in English | MEDLINE | ID: mdl-15060445

14.

Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner.

Yaqub, Sheraz; Henjum, Karen; Mahic, Milada; Jahnsen, Frode L; Aandahl, Einar M; Bjørnbeth, Bjørn A; Taskén, Kjetil.

Cancer Immunol Immunother ; 57(6): 813-21, 2008 Jun.

Article in English | MEDLINE | ID: mdl-17962941

15.

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin.

Ruppelt, Anja; Mosenden, Randi; Grönholm, Mikaela; Aandahl, Einar M; Tobin, Derek; Carlson, Cathrine R; Abrahamsen, Hilde; Herberg, Friedrich W; Carpén, Olli; Taskén, Kjetil.

J Immunol ; 179(8): 5159-68, 2007 Oct 15.

Article in English | MEDLINE | ID: mdl-17911601

16.

FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism.

Mahic, Milada; Yaqub, Sheraz; Johansson, C Christian; Taskén, Kjetil; Aandahl, Einar M.

J Immunol ; 177(1): 246-54, 2006 Jul 01.

Article in English | MEDLINE | ID: mdl-16785520

17.

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens.

Aandahl, Einar M; Michaëlsson, Jakob; Moretto, Walter J; Hecht, Frederick M; Nixon, Douglas F.

J Virol ; 78(5): 2454-9, 2004 Mar.

Article in English | MEDLINE | ID: mdl-14963140

18.

CD7 is a differentiation marker that identifies multiple CD8 T cell effector subsets.

Aandahl, Einar M; Sandberg, Johan K; Beckerman, Karen P; Taskén, Kjetil; Moretto, Walter J; Nixon, Douglas F.

J Immunol ; 170(5): 2349-55, 2003 Mar 01.

Article in English | MEDLINE | ID: mdl-12594257

19.

A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha.

Johansson, C Christian; Dahle, Maria K; Blomqvist, Sandra Rodrigo; Grønning, Line M; Aandahl, Einar M; Enerbäck, Sven; Taskén, Kjetil.

J Biol Chem ; 278(19): 17573-9, 2003 May 09.

Article in English | MEDLINE | ID: mdl-12621056

20.

Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment.

Aandahl, Einar M; Quigley, Máire F; Moretto, Walter J; Moll, Markus; Gonzalez, Veronica D; Sönnerborg, Anders; Lindbäck, Stefan; Hecht, Frederick M; Deeks, Steven G; Rosenberg, Michael G; Nixon, Douglas F; Sandberg, Johan K.

Blood ; 104(12): 3672-8, 2004 Dec 01.

Article in English | MEDLINE | ID: mdl-15308569

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