Search | VHL Search Portal

1.

Non-viral precision T cell receptor replacement for personalized cell therapy.

Foy, Susan P; Jacoby, Kyle; Bota, Daniela A; Hunter, Theresa; Pan, Zheng; Stawiski, Eric; Ma, Yan; Lu, William; Peng, Songming; Wang, Clifford L; Yuen, Benjamin; Dalmas, Olivier; Heeringa, Katharine; Sennino, Barbara; Conroy, Andy; Bethune, Michael T; Mende, Ines; White, William; Kukreja, Monica; Gunturu, Swetha; Humphrey, Emily; Hussaini, Adeel; An, Duo; Litterman, Adam J; Quach, Boi Bryant; Ng, Alphonsus H C; Lu, Yue; Smith, Chad; Campbell, Katie M; Anaya, Daniel; Skrdlant, Lindsey; Huang, Eva Yi-Hsuan; Mendoza, Ventura; Mathur, Jyoti; Dengler, Luke; Purandare, Bhamini; Moot, Robert; Yi, Michael C; Funke, Roel; Sibley, Alison; Stallings-Schmitt, Todd; Oh, David Y; Chmielowski, Bartosz; Abedi, Mehrdad; Yuan, Yuan; Sosman, Jeffrey A; Lee, Sylvia M; Schoenfeld, Adam J; Baltimore, David; Heath, James R.

Nature ; 615(7953): 687-696, 2023 03.

Article in English | MEDLINE | ID: mdl-36356599

2.

Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects.

Khuat, Lam T; Vick, Logan V; Dunai, Cordelia; Collins, Craig P; More, Shyam K; Le, Catherine T; Pai, Chien-Chun Steven; Stoffel, Kevin M; Maverakis, Emanual; Canter, Robert J; Monjazeb, Arta M; Longo, Dan L; Abedi, Mehrdad; Choi, Eunju; Blazar, Bruce R; Dave, Maneesh; Murphy, William J.

Blood ; 138(24): 2583-2588, 2021 12 16.

Article in English | MEDLINE | ID: mdl-34424962

3.

KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results.

Shah, Bijal D; Bishop, Michael R; Oluwole, Olalekan O; Logan, Aaron C; Baer, Maria R; Donnellan, William B; O'Dwyer, Kristen M; Holmes, Houston; Arellano, Martha L; Ghobadi, Armin; Pagel, John M; Lin, Yi; Cassaday, Ryan D; Park, Jae H; Abedi, Mehrdad; Castro, Januario E; DeAngelo, Daniel J; Malone, Adriana K; Mawad, Raya; Schiller, Gary J; Rossi, John M; Bot, Adrian; Shen, Tong; Goyal, Lovely; Jain, Rajul K; Vezan, Remus; Wierda, William G.

Blood ; 138(1): 11-22, 2021 07 08.

Article in English | MEDLINE | ID: mdl-33827116

4.

KTE-X19 for relapsed or refractory adult B-cell acute lymphoblastic leukaemia: phase 2 results of the single-arm, open-label, multicentre ZUMA-3 study.

Shah, Bijal D; Ghobadi, Armin; Oluwole, Olalekan O; Logan, Aaron C; Boissel, Nicolas; Cassaday, Ryan D; Leguay, Thibaut; Bishop, Michael R; Topp, Max S; Tzachanis, Dimitrios; O'Dwyer, Kristen M; Arellano, Martha L; Lin, Yi; Baer, Maria R; Schiller, Gary J; Park, Jae H; Subklewe, Marion; Abedi, Mehrdad; Minnema, Monique C; Wierda, William G; DeAngelo, Daniel J; Stiff, Patrick; Jeyakumar, Deepa; Feng, Chaoling; Dong, Jinghui; Shen, Tong; Milletti, Francesca; Rossi, John M; Vezan, Remus; Masouleh, Behzad Kharabi; Houot, Roch.

Lancet ; 398(10299): 491-502, 2021 08 07.

Article in English | MEDLINE | ID: mdl-34097852

5.

Therapeutic Effects of a NEDD8-Activating Enzyme Inhibitor, Pevonedistat, on Sclerodermatous Graft-versus-Host Disease in Mice.

Pai, Chien-Chun Steven; Khuat, Lam T; Chen, Mingyi; Murphy, William J; Abedi, Mehrdad.

Biol Blood Marrow Transplant ; 23(1): 30-37, 2017 01.

Article in English | MEDLINE | ID: mdl-27815049

6.

Phase I Trial of Anti-PSMA Designer CAR-T Cells in Prostate Cancer: Possible Role for Interacting Interleukin 2-T Cell Pharmacodynamics as a Determinant of Clinical Response.

Junghans, Richard P; Ma, Qiangzhong; Rathore, Ritesh; Gomes, Erica M; Bais, Anthony J; Lo, Agnes S Y; Abedi, Mehrdad; Davies, Robin A; Cabral, Howard J; Al-Homsi, A Samer; Cohen, Stephen I.

Prostate ; 76(14): 1257-70, 2016 10.

Article in English | MEDLINE | ID: mdl-27324746

7.

Treatment of chronic graft-versus-host disease with bortezomib.

Pai, Chien-Chun Steven; Chen, Mingyi; Mirsoian, Annie; Grossenbacher, Steven K; Tellez, Joseph; Ames, Erik; Sun, Kai; Jagdeo, Jared; Blazar, Bruce R; Murphy, William J; Abedi, Mehrdad.

Blood ; 124(10): 1677-88, 2014 Sep 04.

Article in English | MEDLINE | ID: mdl-25009225

8.

Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells.

Barclay, Sharlie L; Yang, Yimin; Zhang, Siruo; Fong, Ryan; Barraza, Alfonso; Nolta, Jan A; Torbett, Bruce E; Abedi, Mehrdad; Bauer, Gerhard; Anderson, Joseph S.

Stem Cells ; 33(3): 870-9, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25524029

9.

Phase I study of escalating doses of carfilzomib with HyperCVAD in patients with newly diagnosed acute lymphoblastic leukemia.

Jonas, Brian A; Fisch, Samantha C; Rosenberg, Aaron S; Hoeg, Rasmus T; Tuscano, Joseph M; Abedi, Mehrdad.

Am J Hematol ; 96(4): E114-E117, 2021 04 01.

Article in English | MEDLINE | ID: mdl-33476436

10.

The path(way) less traveled.

Abedi, Mehrdad; Murphy, William J.

Blood ; 122(12): 1996-7, 2013 Sep 19.

Article in English | MEDLINE | ID: mdl-24052539

11.

Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels.

Pai, Chien-Chun Steven; Hsiao, Hui-Hua; Sun, Kai; Chen, Mingyi; Hagino, Takeshi; Tellez, Joseph; Mall, Christine; Blazar, Bruce R; Monjazeb, Arta; Abedi, Mehrdad; Murphy, William J.

Biol Blood Marrow Transplant ; 20(12): 1899-904, 2014 Dec.

Article in English | MEDLINE | ID: mdl-25064746

12.

Lenalidomide plus rituximab can produce durable clinical responses in patients with relapsed or refractory, indolent non-Hodgkin lymphoma.

Tuscano, Joseph M; Dutia, Mrinal; Chee, Karen; Brunson, Ann; Reed-Pease, Christine; Abedi, Mehrdad; Welborn, Jeanna; O'Donnell, Robert T.

Br J Haematol ; 165(3): 375-81, 2014 May.

Article in English | MEDLINE | ID: mdl-24606326

13.

A phase II study of bortezomib in combination with pegylated liposomal doxorubicin for acute myeloid leukemia.

Tomlinson, Benjamin K; Tuscano, Joseph M; Abedi, Mehrdad; Welborn, Jeanna; Arora, Mili; O'Donnell, Robert T; Wun, Ted; Jonas, Brian A.

Am J Hematol ; 94(11): E291-E294, 2019 11.

Article in English | MEDLINE | ID: mdl-31379016

14.

IFN-Î³ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation.

Sun, Kai; Hsiao, Hui-Hua; Li, Minghui; Ames, Erik; Bouchlaka, Myriam; Welniak, Lisbeth A; Hagino, Takeshi; Jagdeo, Jared; Pai, Chien-Chun; Chen, Mingyi; Blazar, Bruce R; Abedi, Mehrdad; Murphy, William J.

J Immunol ; 189(4): 2033-42, 2012 Aug 15.

Article in English | MEDLINE | ID: mdl-22778394

15.

Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice.

Amenta, Alison R; Yilmaz, Atilgan; Bogdanovich, Sasha; McKechnie, Beth A; Abedi, Mehrdad; Khurana, Tejvir S; Fallon, Justin R.

Proc Natl Acad Sci U S A ; 108(2): 762-7, 2011 Jan 11.

Article in English | MEDLINE | ID: mdl-21187385

16.

Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.

Walker, Jon E; Chen, Rachel X; McGee, Jeannine; Nacey, Catherine; Pollard, Richard B; Abedi, Mehrdad; Bauer, Gerhard; Nolta, Jan A; Anderson, Joseph S.

J Virol ; 86(10): 5719-29, 2012 May.

Article in English | MEDLINE | ID: mdl-22398281

17.

Transplantation Referral Patterns for Patients with Newly Diagnosed Higher-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia at Academic and Community Sites in the Connect® Myeloid Disease Registry: Potential Barriers to Care.

Tomlinson, Benjamin; de Lima, Marcos; Cogle, Christopher R; Thompson, Michael A; Grinblatt, David L; Pollyea, Daniel A; Komrokji, Rami S; Roboz, Gail J; Savona, Michael R; Sekeres, Mikkael A; Abedi, Mehrdad; Garcia-Manero, Guillermo; Kurtin, Sandra E; Maciejewski, Jaroslaw P; Patel, Jay L; Revicki, Dennis A; George, Tracy I; Flick, E Dawn; Kiselev, Pavel; Louis, Chrystal U; DeGutis, Irene S; Nifenecker, Melissa; Erba, Harry P; Steensma, David P; Scott, Bart L.

Transplant Cell Ther ; 29(7): 460.e1-460.e9, 2023 07.

Article in English | MEDLINE | ID: mdl-37086851

18.

Impact of prior therapies and subsequent transplantation on outcomes in adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3.

Shah, Bijal D; Cassaday, Ryan D; Park, Jae H; Houot, Roch; Oluwole, Olalekan O; Logan, Aaron C; Boissel, Nicolas; Leguay, Thibaut; Bishop, Michael R; Topp, Max S; Tzachanis, Dimitrios; O'Dwyer, Kristen M; Arellano, Martha L; Lin, Yi; Baer, Maria R; Schiller, Gary J; Subklewe, Marion; Abedi, Mehrdad; Minnema, Monique C; Wierda, William G; DeAngelo, Daniel J; Stiff, Patrick J; Jeyakumar, Deepa; Mao, Daqin; Adhikary, Sabina; Zhou, Lang; Schuberth, Petra C; Damico Khalid, Rita; Ghobadia, Armin.

J Immunother Cancer ; 11(8)2023 08.

Article in English | MEDLINE | ID: mdl-37648261

19.

Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.

Bota, Daniela A; Taylor, Thomas H; Piccioni, David E; Duma, Christopher M; LaRocca, Renato V; Kesari, Santosh; Carrillo, Jose A; Abedi, Mehrdad; Aiken, Robert D; Hsu, Frank P K; Kong, Xiao-Tang; Hsieh, Candace; Bota, Peter G; Nistor, Gabriel I; Keirstead, Hans S; Dillman, Robert O.

J Exp Clin Cancer Res ; 41(1): 344, 2022 Dec 14.

Article in English | MEDLINE | ID: mdl-36517865

20.

Clinical experience with frontline Hyper-CVAD-based regimens, including Hyper-CVAD plus ponatinib, in patients with acute lymphoblastic leukemia treated at a comprehensive cancer center.

Othman, Tamer; Moskoff, Benjamin N; Ho, Gwendolyn; Tenold, Matthew E; Azenkot, Tali; Krackeler, Margaret L; Fisch, Samantha C; Potter, Laura A; Kaesberg, Paul R; Welborn, Jeanna L; Wun, Ted; Esteghamat, Naseem S; Hoeg, Rasmus T; Rosenberg, Aaron S; Abedi, Mehrdad; Tuscano, Joseph M; Jonas, Brian A.

Leuk Res ; 119: 106885, 2022 08.

Article in English | MEDLINE | ID: mdl-35738024

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: