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1.

Cancer immunotherapy: T cells and neutrophils working together to attack cancers.

Ager, Ann.

Cell ; 186(7): 1304-1306, 2023 03 30.

Article in English | MEDLINE | ID: mdl-37001496

2.

Author Correction: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.

Crowther, Michael D; Dolton, Garry; Legut, Mateusz; Caillaud, Marine E; Lloyd, Angharad; Attaf, Meriem; Galloway, Sarah A E; Rius, Cristina; Farrell, Colin P; Szomolay, Barbara; Ager, Ann; Parker, Alan L; Fuller, Anna; Donia, Marco; McCluskey, James; Rossjohn, Jamie; Svane, Inge Marie; Phillips, John D; Sewell, Andrew K.

Nat Immunol ; 21(6): 695, 2020 06.

Article in English | MEDLINE | ID: mdl-32123375

3.

Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.

Crowther, Michael D; Dolton, Garry; Legut, Mateusz; Caillaud, Marine E; Lloyd, Angharad; Attaf, Meriem; Galloway, Sarah A E; Rius, Cristina; Farrell, Colin P; Szomolay, Barbara; Ager, Ann; Parker, Alan L; Fuller, Anna; Donia, Marco; McCluskey, James; Rossjohn, Jamie; Svane, Inge Marie; Phillips, John D; Sewell, Andrew K.

Nat Immunol ; 21(2): 178-185, 2020 02.

Article in English | MEDLINE | ID: mdl-31959982

4.

Standing up for immunology.

Ager, Ann.

Nat Immunol ; 21(3): 239-240, 2020 03.

Article in English | MEDLINE | ID: mdl-32094646

5.

Alzheimer's disease-associated P460L variant of EphA1 dysregulates receptor activity and blood-brain barrier function.

Owens, Helen A; Thorburn, Lauren E; Walsby, Elisabeth; Moon, Owen R; Rizkallah, Pierre; Sherwani, Subuhi; Tinsley, Caroline L; Rogers, Louise; Cerutti, Camilla; Ridley, Anne J; Williams, Julie; Knäuper, Vera; Ager, Ann.

Alzheimers Dement ; 20(3): 2016-2033, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38184788

6.

Molecular pathology of Lynch syndrome.

Cerretelli, Guia; Ager, Ann; Arends, Mark J; Frayling, Ian M.

J Pathol ; 250(5): 518-531, 2020 04.

Article in English | MEDLINE | ID: mdl-32141610

7.

Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion.

Hughes, Ellyn; Lauder, Sarah N; Smart, Kathryn; Bloom, Anja; Scott, Jake; Jones, Emma; Somerville, Michelle; Browne, Molly; Blainey, Andrew; Godkin, Andrew; Ager, Ann; Gallimore, Awen.

Cancer Immunol Immunother ; 69(10): 2063-2073, 2020 Oct.

Article in English | MEDLINE | ID: mdl-32447412

8.

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking.

Sinclair, Linda V; Finlay, David; Feijoo, Carmen; Cornish, Georgina H; Gray, Alex; Ager, Ann; Okkenhaug, Klaus; Hagenbeek, Thijs J; Spits, Hergen; Cantrell, Doreen A.

Nat Immunol ; 9(5): 513-21, 2008 May.

Article in English | MEDLINE | ID: mdl-18391955

9.

High endothelial venules are associated with microsatellite instability, hereditary background and immune evasion in colorectal cancer.

Pfuderer, Pauline L; Ballhausen, Alexej; Seidler, Florian; Stark, Hans-Jürgen; Grabe, Niels; Frayling, Ian M; Ager, Ann; von Knebel Doeberitz, Magnus; Kloor, Matthias; Ahadova, Aysel.

Br J Cancer ; 121(5): 395-404, 2019 08.

Article in English | MEDLINE | ID: mdl-31358939

10.

Lynch syndrome - cancer pathways, heterogeneity and immune escape.

Seth, Sidhant; Ager, Ann; Arends, Mark J; Frayling, Ian M.

J Pathol ; 246(2): 129-133, 2018 10.

Article in English | MEDLINE | ID: mdl-30027543

11.

TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer.

Gawel-Beben, Katarzyna; Ali, Nazim; Ellis, Vincent; Velasco, Gloria; Poghosyan, Zaruhi; Ager, Ann; Knäuper, Vera.

Cell Biol Int ; 42(3): 273-280, 2018 Mar.

Article in English | MEDLINE | ID: mdl-28762604

12.

Purity of transferred CD8(+) T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1.

Watson, H Angharad; Dolton, Garry; Ohme, Julia; Ladell, Kristin; Vigar, Miriam; Wehenkel, Sophie; Hindley, James; Mohammed, Rebar N; Miners, Kelly; Luckwell, Rhys A; Price, David A; Matthews, R James; Ager, Ann.

Immunol Cell Biol ; 94(8): 802-8, 2016 09.

Article in English | MEDLINE | ID: mdl-27430370

13.

SHP-1: the next checkpoint target for cancer immunotherapy?

Watson, H Angharad; Wehenkel, Sophie; Matthews, James; Ager, Ann.

Biochem Soc Trans ; 44(2): 356-62, 2016 Apr 15.

Article in English | MEDLINE | ID: mdl-27068940

14.

Homing to solid cancers: a vascular checkpoint in adoptive cell therapy using CAR T-cells.

Ager, Ann; Watson, H Angharad; Wehenkel, Sophie C; Mohammed, Rebar N.

Biochem Soc Trans ; 44(2): 377-85, 2016 Apr 15.

Article in English | MEDLINE | ID: mdl-27068943

15.

Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation.

Spary, Lisa K; Al-Taei, Saly; Salimu, Josephine; Cook, Alexander D; Ager, Ann; Watson, H Angharad; Clayton, Aled; Staffurth, John; Mason, Malcolm D; Tabi, Zsuzsanna.

J Immunol ; 192(7): 3101-10, 2014 Apr 01.

Article in English | MEDLINE | ID: mdl-24600032

16.

A distinct chemokine axis does not account for enrichment of Foxp3(+) CD4(+) T cells in carcinogen-induced fibrosarcomas.

Ondondo, Beatrice; Colbeck, Emily; Jones, Emma; Smart, Kathryn; Lauder, Sarah N; Hindley, James; Godkin, Andrew; Moser, Bernhard; Ager, Ann; Gallimore, Awen.

Immunology ; 145(1): 94-104, 2015 May.

Article in English | MEDLINE | ID: mdl-25495686

17.

Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cells via blood vessels and lymphatics.

Ondondo, Beatrice; Jones, Emma; Hindley, James; Cutting, Scott; Smart, Kathryn; Bridgeman, Hayley; Matthews, Katherine K; Ladell, Kristin; Price, David A; Jackson, David G; Godkin, Andrew; Ager, Ann; Gallimore, Awen.

Int J Cancer ; 134(9): 2156-67, 2014 May 01.

Article in English | MEDLINE | ID: mdl-24142504

18.

Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity.

Humphreys, Ian R; Clement, Mathew; Marsden, Morgan; Ladell, Kristin; McLaren, James E; Smart, Kathryn; Hindley, James P; Bridgeman, Hayley M; van den Berg, Hugo A; Price, David A; Ager, Ann; Wooldridge, Linda; Godkin, Andrew; Gallimore, Awen M.

Eur J Immunol ; 42(12): 3235-42, 2012 Dec.

Article in English | MEDLINE | ID: mdl-22965681

19.

Immune Responses to IAV Infection and the Roles of L-Selectin and ADAM17 in Lymphocyte Homing.

Reed, Sophie G; Ager, Ann.

Pathogens ; 11(2)2022 Jan 25.

Article in English | MEDLINE | ID: mdl-35215094

20.

Drug Inhibition of Redox Factor-1 Restores Hypoxia-Driven Changes in Tuberous Sclerosis Complex 2 Deficient Cells.

Champion, Jesse D; Dodd, Kayleigh M; Lam, Hilaire C; Alzahrani, Mohammad A M; Seifan, Sara; Rad, Ellie; Scourfield, David Oliver; Fishel, Melissa L; Calver, Brian L; Ager, Ann; Henske, Elizabeth P; Davies, David Mark; Kelley, Mark R; Tee, Andrew R.

Cancers (Basel) ; 14(24)2022 Dec 15.

Article in English | MEDLINE | ID: mdl-36551683

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