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1.

Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis.

Rheault, Michelle N; Alpers, Charles E; Barratt, Jonathan; Bieler, Stewart; Canetta, Pietro; Chae, Dong-Wan; Coppock, Gaia; Diva, Ulysses; Gesualdo, Loreto; Heerspink, Hiddo J L; Inrig, Jula K; Kirsztajn, Gianna M; Kohan, Donald; Komers, Radko; Kooienga, Laura A; Lieberman, Kenneth; Mercer, Alex; Noronha, Irene L; Perkovic, Vlado; Radhakrishnan, Jai; Rote, William; Rovin, Brad; Tesar, Vladimir; Trimarchi, Hernán; Tumlin, James; Wong, Muh Geot; Trachtman, Howard.

N Engl J Med ; 389(26): 2436-2445, 2023 Dec 28.

Article in English | MEDLINE | ID: mdl-37921461

2.

Seeing through the density of dense deposit disease.

Alpers, Charles E.

Kidney Int ; 105(5): 929-931, 2024 May.

Article in English | MEDLINE | ID: mdl-38642992

3.

Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial.

Heerspink, Hiddo J L; Radhakrishnan, Jai; Alpers, Charles E; Barratt, Jonathan; Bieler, Stewart; Diva, Ulysses; Inrig, Jula; Komers, Radko; Mercer, Alex; Noronha, Irene L; Rheault, Michelle N; Rote, William; Rovin, Brad; Trachtman, Howard; Trimarchi, Hernán; Wong, Muh Geot; Perkovic, Vlado.

Lancet ; 401(10388): 1584-1594, 2023 05 13.

Article in English | MEDLINE | ID: mdl-37015244

4.

Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial.

Rovin, Brad H; Barratt, Jonathan; Heerspink, Hiddo J L; Alpers, Charles E; Bieler, Stewart; Chae, Dong-Wan; Diva, Ulysses A; Floege, Jürgen; Gesualdo, Loreto; Inrig, Jula K; Kohan, Donald E; Komers, Radko; Kooienga, Laura Ann; Lafayette, Richard; Maes, Bart; Malecki, Robert; Mercer, Alex; Noronha, Irene L; Oh, Se Won; Peh, Chen Au; Praga, Manuel; Preciado, Priscila; Radhakrishnan, Jai; Rheault, Michelle N; Rote, William E; Tang, Sydney C W; Tesar, Vladimir; Trachtman, Howard; Trimarchi, Hernán; Tumlin, James A; Wong, Muh Geot; Perkovic, Vlado.

Lancet ; 402(10417): 2077-2090, 2023 12 02.

Article in English | MEDLINE | ID: mdl-37931634

5.

Lupus nephritis transcriptomics across space and time.

Jackson, Shaun W; Alpers, Charles E.

Kidney Int ; 102(4): 694-696, 2022 10.

Article in English | MEDLINE | ID: mdl-36150761

6.

Digital spatial profiling of collapsing glomerulopathy.

Smith, Kelly D; Prince, David K; Henriksen, Kammi J; Nicosia, Roberto F; Alpers, Charles E; Akilesh, Shreeram.

Kidney Int ; 101(5): 1017-1026, 2022 05.

Article in English | MEDLINE | ID: mdl-35227689

7.

Molecular mechanisms and therapeutic targets for diabetic kidney disease.

Tuttle, Katherine R; Agarwal, Rajiv; Alpers, Charles E; Bakris, George L; Brosius, Frank C; Kolkhof, Peter; Uribarri, Jaime.

Kidney Int ; 102(2): 248-260, 2022 08.

Article in English | MEDLINE | ID: mdl-35661785

8.

TACI haploinsufficiency protects against BAFF-driven humoral autoimmunity in mice.

Jacobs, Holly M; Arkatkar, Tanvi; Du, Samuel W; Scharping, Nicole E; Woods, Jonathan; Li, Quan-Zhen; Hudkins, Kelly L; Alpers, Charles E; Rawlings, David J; Jackson, Shaun W.

Eur J Immunol ; 51(9): 2225-2236, 2021 09.

Article in English | MEDLINE | ID: mdl-34146342

9.

Characterizing Viral Infection by Electron Microscopy: Lessons from the Coronavirus Disease 2019 Pandemic.

Akilesh, Shreeram; Nicosia, Roberto F; Alpers, Charles E; Tretiakova, Maria; Hsiang, Tien-Ying; Gale, Michael; Smith, Kelly D.

Am J Pathol ; 191(2): 222-227, 2021 02.

Article in English | MEDLINE | ID: mdl-33227297

10.

Approach to Kidney Biopsy: Core Curriculum 2022.

Najafian, Behzad; Lusco, Mark A; Alpers, Charles E; Fogo, Agnes B.

Am J Kidney Dis ; 80(1): 119-131, 2022 07.

Article in English | MEDLINE | ID: mdl-35125261

11.

Regression of diabetic nephropathy by treatment with empagliflozin in BTBR ob/ob mice.

Hudkins, Kelly L; Li, Xianwu; Holland, Alexander L; Swaminathan, Shreya; Alpers, Charles E.

Nephrol Dial Transplant ; 37(5): 847-859, 2022 04 25.

Article in English | MEDLINE | ID: mdl-34865099

12.

Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury.

Skopelja-Gardner, Sladjana; Colonna, Lucrezia; Hermanson, Payton; Sun, Xizhang; Tanaka, Lena; Tai, Joyce; Nguyen, Yenly; Snyder, Jessica M; Alpers, Charles E; Hudkins, Kelly L; Salant, David J; Peng, YuFeng; Elkon, Keith B.

J Immunol ; 204(10): 2627-2640, 2020 05 15.

Article in English | MEDLINE | ID: mdl-32238460

13.

A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.

El-Achkar, Tarek M; Eadon, Michael T; Menon, Rajasree; Lake, Blue B; Sigdel, Tara K; Alexandrov, Theodore; Parikh, Samir; Zhang, Guanshi; Dobi, Dejan; Dunn, Kenneth W; Otto, Edgar A; Anderton, Christopher R; Carson, Jonas M; Luo, Jinghui; Park, Chris; Hamidi, Habib; Zhou, Jian; Hoover, Paul; Schroeder, Andrew; Joanes, Marianinha; Azeloglu, Evren U; Sealfon, Rachel; Winfree, Seth; Steck, Becky; He, Yongqun; D'Agati, Vivette; Iyengar, Ravi; Troyanskaya, Olga G; Barisoni, Laura; Gaut, Joseph; Zhang, Kun; Laszik, Zoltan; Rovin, Brad H; Dagher, Pierre C; Sharma, Kumar; Sarwal, Minnie M; Hodgin, Jeffrey B; Alpers, Charles E; Kretzler, Matthias; Jain, Sanjay.

Physiol Genomics ; 53(1): 1-11, 2021 01 01.

Article in English | MEDLINE | ID: mdl-33197228

14.

Reversal of hypertriglyceridemia in diabetic BTBR ob/ob mice does not prevent nephropathy.

Attie, Alan D; Schueler, Kathryn M; Keller, Mark P; Mitok, Kelly A; Simonett, Shane P; Hudkins, Kelly L; Mehrotra, Kunaal; Graham, Mark J; Lee, Richard G; Alpers, Charles E.

Lab Invest ; 101(7): 935-941, 2021 07.

Article in English | MEDLINE | ID: mdl-33911188

15.

Rationale and design of the Kidney Precision Medicine Project.

de Boer, Ian H; Alpers, Charles E; Azeloglu, Evren U; Balis, Ulysses G J; Barasch, Jonathan M; Barisoni, Laura; Blank, Kristina N; Bomback, Andrew S; Brown, Keith; Dagher, Pierre C; Dighe, Ashveena L; Eadon, Michael T; El-Achkar, Tarek M; Gaut, Joseph P; Hacohen, Nir; He, Yongqun; Hodgin, Jeffrey B; Jain, Sanjay; Kellum, John A; Kiryluk, Krzysztof; Knight, Richard; Laszik, Zoltan G; Lienczewski, Chrysta; Mariani, Laura H; McClelland, Robyn L; Menez, Steven; Moledina, Dennis G; Mooney, Sean D; O'Toole, John F; Palevsky, Paul M; Parikh, Chirag R; Poggio, Emilio D; Rosas, Sylvia E; Rosengart, Matthew R; Sarwal, Minnie M; Schaub, Jennifer A; Sedor, John R; Sharma, Kumar; Steck, Becky; Toto, Robert D; Troyanskaya, Olga G; Tuttle, Katherine R; Vazquez, Miguel A; Waikar, Sushrut S; Williams, Kayleen; Wilson, Francis Perry; Zhang, Kun; Iyengar, Ravi; Kretzler, Matthias; Himmelfarb, Jonathan.

Kidney Int ; 99(3): 498-510, 2021 03.

Article in English | MEDLINE | ID: mdl-33637194

16.

Multicenter Clinicopathologic Correlation of Kidney Biopsies Performed in COVID-19 Patients Presenting With Acute Kidney Injury or Proteinuria.

Akilesh, Shreeram; Nast, Cynthia C; Yamashita, Michifumi; Henriksen, Kammi; Charu, Vivek; Troxell, Megan L; Kambham, Neeraja; Bracamonte, Erika; Houghton, Donald; Ahmed, Naila I; Chong, Chyi Chyi; Thajudeen, Bijin; Rehman, Shehzad; Khoury, Firas; Zuckerman, Jonathan E; Gitomer, Jeremy; Raguram, Parthassarathy C; Mujeeb, Shanza; Schwarze, Ulrike; Shannon, M Brendan; De Castro, Iris; Alpers, Charles E; Najafian, Behzad; Nicosia, Roberto F; Andeen, Nicole K; Smith, Kelly D.

Am J Kidney Dis ; 77(1): 82-93.e1, 2021 01.

Article in English | MEDLINE | ID: mdl-33045255

17.

Beneficial effect on podocyte number in experimental diabetic nephropathy resulting from combined atrasentan and RAAS inhibition therapy.

Hudkins, Kelly L; Wietecha, Tomasz A; Steegh, Floor; Alpers, Charles E.

Am J Physiol Renal Physiol ; 318(5): F1295-F1305, 2020 05 01.

Article in English | MEDLINE | ID: mdl-32249614

18.

High-protein diet accelerates diabetes and kidney disease in the BTBRob/ob mouse.

Björnson Granqvist, Anna; Ericsson, Anette; Sanchez, José; Tonelius, Pernilla; William-Olsson, Lena; Dahlqvist, Ulrika; Andersson, Ann-Katrin; Tesan Tomic, Tajana; Hudkins, Kelly; Alpers, Charles E; Pellegrini, Giovanni; Söderberg, Magnus.

Am J Physiol Renal Physiol ; 318(3): F763-F771, 2020 03 01.

Article in English | MEDLINE | ID: mdl-31961715

19.

Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci.

Sieber, Karsten B; Batorsky, Anna; Siebenthall, Kyle; Hudkins, Kelly L; Vierstra, Jeff D; Sullivan, Shawn; Sur, Aakash; McNulty, Michelle; Sandstrom, Richard; Reynolds, Alex; Bates, Daniel; Diegel, Morgan; Dunn, Douglass; Nelson, Jemma; Buckley, Michael; Kaul, Rajinder; Sampson, Matthew G; Himmelfarb, Jonathan; Alpers, Charles E; Waterworth, Dawn; Akilesh, Shreeram.

J Am Soc Nephrol ; 30(3): 421-441, 2019 Mar.

Article in English | MEDLINE | ID: mdl-30760496

20.

Gene deletion of the Na⁺-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion.

Nespoux, Josselin; Patel, Rohit; Hudkins, Kelly L; Huang, Winnie; Freeman, Brent; Kim, Young Chul; Koepsell, Hermann; Alpers, Charles E; Vallon, Volker.

Am J Physiol Renal Physiol ; 316(6): F1201-F1210, 2019 06 01.

Article in English | MEDLINE | ID: mdl-30995111

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