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1.
Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity.
Mol Psychiatry
; 27(5): 2533-2545, 2022 05.
Article
in English
| MEDLINE | ID: mdl-35256747
2.
The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice.
Mol Psychiatry
; 26(7): 3060-3076, 2021 07.
Article
in English
| MEDLINE | ID: mdl-33649453
3.
Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity.
Angew Chem Int Ed Engl
; 60(24): 13257-13263, 2021 06 07.
Article
in English
| MEDLINE | ID: mdl-33843131
4.
A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2.
Hum Mutat
; 41(1): 169-181, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31464095
5.
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Nat Commun
; 15(1): 2635, 2024 Mar 25.
Article
in English
| MEDLINE | ID: mdl-38528004
6.
Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice.
Sci Signal
; 17(834): eadj6603, 2024 Apr 30.
Article
in English
| MEDLINE | ID: mdl-38687825
7.
Loss of function of FIP200 in human pluripotent stem cell-derived neurons leads to axonal pathology and hyperactivity.
Transl Psychiatry
; 13(1): 143, 2023 05 03.
Article
in English
| MEDLINE | ID: mdl-37137886
8.
Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
Am J Psychiatry
; 180(10): 739-754, 2023 10 01.
Article
in English
| MEDLINE | ID: mdl-37491937
9.
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
bioRxiv
; 2023 Apr 03.
Article
in English
| MEDLINE | ID: mdl-37066393
10.
FKBP5/FKBP51 on weight watch: central FKBP5 links regulatory WIPI protein networks to autophagy and metabolic control.
Autophagy
; 18(11): 2756-2758, 2022 11.
Article
in English
| MEDLINE | ID: mdl-35438043
11.
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism.
Sci Adv
; 8(10): eabi4797, 2022 03 11.
Article
in English
| MEDLINE | ID: mdl-35263141
12.
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning.
Cell Rep
; 41(10): 111766, 2022 12 06.
Article
in English
| MEDLINE | ID: mdl-36476872
13.
Chemical Phosphoproteomics Sheds New Light on the Targets and Modes of Action of AKT Inhibitors.
ACS Chem Biol
; 16(4): 631-641, 2021 04 16.
Article
in English
| MEDLINE | ID: mdl-33755436
14.
Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice.
Front Aging Neurosci
; 13: 731603, 2021.
Article
in English
| MEDLINE | ID: mdl-34867270
15.
Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5.
Cell Rep
; 35(9): 109185, 2021 06 01.
Article
in English
| MEDLINE | ID: mdl-34077736
16.
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Nat Commun
; 12(1): 4643, 2021 07 30.
Article
in English
| MEDLINE | ID: mdl-34330919
17.
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Nat Commun
; 12(1): 3818, 2021 06 21.
Article
in English
| MEDLINE | ID: mdl-34155207
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