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1.
Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat.
J Virol
; 94(13)2020 06 16.
Article
in English
| MEDLINE | ID: mdl-32295913
2.
Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation.
Bioorg Med Chem Lett
; 47: 128168, 2021 09 01.
Article
in English
| MEDLINE | ID: mdl-34091041
3.
Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence.
Proc Natl Acad Sci U S A
; 115(30): E7139-E7148, 2018 07 24.
Article
in English
| MEDLINE | ID: mdl-29987026
4.
Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation.
Bioorg Med Chem Lett
; 30(13): 127197, 2020 07 01.
Article
in English
| MEDLINE | ID: mdl-32331932
5.
Development of a selective HDAC inhibitor aimed at reactivating the HIV latent reservoir.
Bioorg Med Chem Lett
; 30(17): 127367, 2020 09 01.
Article
in English
| MEDLINE | ID: mdl-32738976
6.
Virologic resistance analysis from a phase 2 study of MK-5172 combined with pegylated interferon/ribavirin in treatment-naive patients with hepatitis C virus genotype 1 infection.
Clin Infect Dis
; 59(12): 1657-65, 2014 Dec 15.
Article
in English
| MEDLINE | ID: mdl-25266289
7.
Combination of vaniprevir with peginterferon and ribavirin significantly increases the rate of SVR in treatment-experienced patients with chronic HCV genotype 1 infection and cirrhosis.
Clin Gastroenterol Hepatol
; 12(6): 1029-37.e5, 2014 Jun.
Article
in English
| MEDLINE | ID: mdl-24120953
8.
Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3.
J Hepatol
; 59(1): 31-7, 2013 Jul.
Article
in English
| MEDLINE | ID: mdl-23454058
9.
Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naïve patients with chronic hepatitis C: a randomized phase II study.
Hepatology
; 56(3): 884-93, 2012 Sep.
Article
in English
| MEDLINE | ID: mdl-22473713
10.
Pharmacodynamic analysis of a serine protease inhibitor, MK-4519, against hepatitis C virus using a novel in vitro pharmacodynamic system.
Antimicrob Agents Chemother
; 56(3): 1170-81, 2012 Mar.
Article
in English
| MEDLINE | ID: mdl-22155837
11.
Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons.
Neuron
; 53(5): 639-47, 2007 Mar 01.
Article
in English
| MEDLINE | ID: mdl-17329205
12.
Switch to a raltegravir-based regimen versus continuation of a lopinavir-ritonavir-based regimen in stable HIV-infected patients with suppressed viraemia (SWITCHMRK 1 and 2): two multicentre, double-blind, randomised controlled trials.
Lancet
; 375(9712): 396-407, 2010 Jan 30.
Article
in English
| MEDLINE | ID: mdl-20074791
13.
Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction.
ACS Med Chem Lett
; 12(4): 540-547, 2021 Apr 08.
Article
in English
| MEDLINE | ID: mdl-33854701
14.
Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity.
J Med Chem
; 64(8): 4709-4729, 2021 04 22.
Article
in English
| MEDLINE | ID: mdl-33797924
15.
Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.
ACS Med Chem Lett
; 12(1): 99-106, 2021 Jan 14.
Article
in English
| MEDLINE | ID: mdl-33488970
16.
Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial.
Lancet
; 374(9692): 796-806, 2009 Sep 05.
Article
in English
| MEDLINE | ID: mdl-19647866
17.
Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.
ACS Med Chem Lett
; 11(12): 2476-2483, 2020 Dec 10.
Article
in English
| MEDLINE | ID: mdl-33335670
18.
Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance.
ACS Med Chem Lett
; 11(7): 1476-1483, 2020 Jul 09.
Article
in English
| MEDLINE | ID: mdl-32676157
19.
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.
EBioMedicine
; 2(8): 874-83, 2015 Aug.
Article
in English
| MEDLINE | ID: mdl-26425694
20.
Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: a population and clonal analysis.
Virology
; 443(2): 278-84, 2013 Sep 01.
Article
in English
| MEDLINE | ID: mdl-23763767