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1.

Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices-A Practical Example.

Fresnais, Margaux; Karabulut, Seda; Abou Zeed, Yasmin; Ungermann, Johannes; Benzel, Julia; Pajtler, Kristian W; Pfister, Stefan M; Haefeli, Walter E; Burhenne, Jürgen; Longuespée, Rémi.

Molecules ; 27(3)2022 Jan 21.

Article in English | MEDLINE | ID: mdl-35163955

2.

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

Sievers, Philipp; Henneken, Sophie C; Blume, Christina; Sill, Martin; Schrimpf, Daniel; Stichel, Damian; Okonechnikov, Konstantin; Reuss, David E; Benzel, Julia; Maaß, Kendra K; Kool, Marcel; Sturm, Dominik; Zheng, Tuyu; Ghasemi, David R; Kohlhof-Meinecke, Patricia; Cruz, Ofelia; Suñol, Mariona; Lavarino, Cinzia; Ruf, Viktoria; Boldt, Henning B; Pagès, Mélanie; Pouget, Celso; Schweizer, Leonille; Kranendonk, Mariëtte E G; Akhtar, Noreen; Bunkowski, Stephanie; Stadelmann, Christine; Schüller, Ulrich; Mueller, Wolf C; Dohmen, Hildegard; Acker, Till; Harter, Patrick N; Mawrin, Christian; Beschorner, Rudi; Brandner, Sebastian; Snuderl, Matija; Abdullaev, Zied; Aldape, Kenneth; Gilbert, Mark R; Armstrong, Terri S; Ellison, David W; Capper, David; Ichimura, Koichi; Reifenberger, Guido; Grundy, Richard G; Jabado, Nada; Krskova, Lenka; Zapotocky, Michal; Vicha, Ales; Varlet, Pascale.

Acta Neuropathol ; 142(5): 827-839, 2021 11.

Article in English | MEDLINE | ID: mdl-34355256

3.

Degradome of soluble ADAM10 and ADAM17 metalloproteases.

Scharfenberg, Franka; Helbig, Andreas; Sammel, Martin; Benzel, Julia; Schlomann, Uwe; Peters, Florian; Wichert, Rielana; Bettendorff, Maximilian; Schmidt-Arras, Dirk; Rose-John, Stefan; Moali, Catherine; Lichtenthaler, Stefan F; Pietrzik, Claus U; Bartsch, Jörg W; Tholey, Andreas; Becker-Pauly, Christoph.

Cell Mol Life Sci ; 77(2): 331-350, 2020 Jan.

Article in English | MEDLINE | ID: mdl-31209506

4.

Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives.

Fresnais, Margaux; Yildirim, Esra; Karabulut, Seda; Jäger, Dirk; Zörnig, Inka; Benzel, Julia; Pajtler, Kristian W; Pfister, Stefan M; Burhenne, Jürgen; Haefeli, Walter E; Longuespée, Rémi.

Molecules ; 26(5)2021 Feb 26.

Article in English | MEDLINE | ID: mdl-33652935

5.

MYCN amplification drives an aggressive form of spinal ependymoma.

Ghasemi, David R; Sill, Martin; Okonechnikov, Konstantin; Korshunov, Andrey; Yip, Stephen; Schutz, Peter W; Scheie, David; Kruse, Anders; Harter, Patrick N; Kastelan, Marina; Wagner, Marlies; Hartmann, Christian; Benzel, Julia; Maass, Kendra K; Khasraw, Mustafa; Sträter, Ronald; Thomas, Christian; Paulus, Werner; Kratz, Christian P; Witt, Hendrik; Kawauchi, Daisuke; Herold-Mende, Christel; Sahm, Felix; Brandner, Sebastian; Kool, Marcel; Jones, David T W; von Deimling, Andreas; Pfister, Stefan M; Reuss, David E; Pajtler, Kristian W.

Acta Neuropathol ; 138(6): 1075-1089, 2019 12.

Article in English | MEDLINE | ID: mdl-31414211

6.

ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance.

Conrad, Catharina; Benzel, Julia; Dorzweiler, Kristina; Cook, Lena; Schlomann, Uwe; Zarbock, Alexander; Slater, Emily P; Nimsky, Christopher; Bartsch, Jörg W.

Clin Sci (Lond) ; 133(1): 83-99, 2019 01 15.

Article in English | MEDLINE | ID: mdl-30635388

7.

Chemoprevention and Treatment of Pancreatic Cancer: Update and Review of the Literature.

Benzel, Julia; Fendrich, Volker.

Digestion ; 97(4): 275-287, 2018.

Article in English | MEDLINE | ID: mdl-29587290

8.

Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.

Wang, Junwen; Voellger, Benjamin; Benzel, Julia; Schlomann, Uwe; Nimsky, Christopher; Bartsch, Jörg W; Carl, Barbara.

Int J Cancer ; 139(6): 1327-39, 2016 09 15.

Article in English | MEDLINE | ID: mdl-27144841

9.

Molecular Characterization and Pathogenesis of Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Benzel, Julia; Fendrich, Volker.

Eur Surg Res ; 55(4): 352-363, 2015 Dec.

Article in English | MEDLINE | ID: mdl-26505881

10.

Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.

Jamaladdin, Nora; Sigaud, Romain; Kocher, Daniela; Kolodziejczak, Anna S; Nonnenbroich, Leo F; Ecker, Jonas; Usta, Diren; Benzel, Julia; Peterziel, Heike; Pajtler, Kristian W; van Tilburg, Cornelis M; Oehme, Ina; Witt, Olaf; Milde, Till.

Clin Pharmacol Ther ; 114(4): 904-913, 2023 10.

Article in English | MEDLINE | ID: mdl-37441736

11.

The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.

Sigaud, Romain; Rösch, Lisa; Gatzweiler, Charlotte; Benzel, Julia; von Soosten, Laura; Peterziel, Heike; Selt, Florian; Najafi, Sara; Ayhan, Simay; Gerloff, Xenia F; Hofmann, Nina; Büdenbender, Isabel; Schmitt, Lukas; Foerster, Kathrin I; Burhenne, Jürgen; Haefeli, Walter E; Korshunov, Andrey; Sahm, Felix; van Tilburg, Cornelis M; Jones, David T W; Pfister, Stefan M; Knoerzer, Deborah; Kreider, Brent L; Sauter, Max; Pajtler, Kristian W; Zuckermann, Marc; Oehme, Ina; Witt, Olaf; Milde, Till.

Neuro Oncol ; 25(3): 566-579, 2023 03 14.

Article in English | MEDLINE | ID: mdl-35882450

12.

Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections.

Fresnais, Margaux; Liang, Siwen; Breitkopf, Marius; Lindner, Joshua Raoul; Claude, Emmanuelle; Pringle, Steven; Levkin, Pavel A; Demir, Konstantin; Benzel, Julia; Sundheimer, Julia; Statz, Britta; Pajtler, Kristian W; Pfister, Stefan M; Haefeli, Walter E; Burhenne, Jürgen; Longuespée, Rémi.

Pharmaceuticals (Basel) ; 15(6)2022 Jun 01.

Article in English | MEDLINE | ID: mdl-35745613

13.

Targeting Aggressive Pituitary Adenomas at the Molecular Level-A Review.

Voellger, Benjamin; Zhang, Zhuo; Benzel, Julia; Wang, Junwen; Lei, Ting; Nimsky, Christopher; Bartsch, Jörg-Walter.

J Clin Med ; 11(1)2021 Dec 27.

Article in English | MEDLINE | ID: mdl-35011868

14.

Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS.

Sauter, Max; Foerster, Kathrin I; Benzel, Julia; Pfister, Stefan; Pajtler, Kristian W; Haefeli, Walter E; Burhenne, Jürgen.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1176: 122781, 2021 Jun 30.

Article in English | MEDLINE | ID: mdl-34051651

15.

Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification.

Benzel, Julia; Bajraktari-Sylejmani, Gzona; Uhl, Philipp; Davis, Abigail; Nair, Sreenath; Pfister, Stefan M; Haefeli, Walter E; Weiss, Johanna; Burhenne, Jürgen; Pajtler, Kristian W; Sauter, Max.

Pharmaceutics ; 13(9)2021 Sep 17.

Article in English | MEDLINE | ID: mdl-34575574

16.

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.

Zheng, Tuyu; Ghasemi, David R; Okonechnikov, Konstantin; Korshunov, Andrey; Sill, Martin; Maass, Kendra K; Benites Goncalves da Silva, Patricia; Ryzhova, Marina; Gojo, Johannes; Stichel, Damian; Arabzade, Amir; Kupp, Robert; Benzel, Julia; Taya, Shinichiro; Adachi, Toma; Shiraishi, Ryo; Gerber, Nicolas U; Sturm, Dominik; Ecker, Jonas; Sievers, Philipp; Selt, Florian; Chapman, Rebecca; Haberler, Christine; Figarella-Branger, Dominique; Reifenberger, Guido; Fleischhack, Gudrun; Rutkowski, Stefan; Donson, Andrew M; Ramaswamy, Vijay; Capper, David; Ellison, David W; Herold-Mende, Christel C; Schüller, Ulrich; Brandner, Sebastian; Driever, Pablo Hernáiz; Kros, Johan M; Snuderl, Matija; Milde, Till; Grundy, Richard G; Hoshino, Mikio; Mack, Stephen C; Gilbertson, Richard J; Jones, David T W; Kool, Marcel; von Deimling, Andreas; Pfister, Stefan M; Sahm, Felix; Kawauchi, Daisuke; Pajtler, Kristian W.

Cancer Discov ; 11(9): 2230-2247, 2021 09.

Article in English | MEDLINE | ID: mdl-33879448

17.

Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT-20 and TtT/GF by affecting expression of MMP-14 and ADAM12.

Zhang, Zhuo; Bartsch, Jörg W; Benzel, Julia; Lei, Ting; Nimsky, Christopher; Voellger, Benjamin.

FEBS Open Bio ; 10(11): 2489-2498, 2020 11.

Article in English | MEDLINE | ID: mdl-33030286

18.

Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling.

Fresnais, Margaux; Muck, Alexander; Majewsky, Marius; Statz, Britta; Krausert, Sonja; Benzel, Julia; Castel, David; Le Dret, Ludivine; Pfister, Stefan; Haefeli, Walter E; Burhenne, Jürgen; Longuespée, Rémi.

J Am Soc Mass Spectrom ; 31(3): 742-751, 2020 Mar 04.

Article in English | MEDLINE | ID: mdl-31971791

19.

Familial Pancreatic Cancer.

Benzel, Julia; Fendrich, Volker.

Oncol Res Treat ; 41(10): 611-618, 2018.

Article in English | MEDLINE | ID: mdl-30269130

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Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices-A Practical Example.

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

Degradome of soluble ADAM10 and ADAM17 metalloproteases.

Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives.

MYCN amplification drives an aggressive form of spinal ependymoma.

ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance.

Chemoprevention and Treatment of Pancreatic Cancer: Update and Review of the Literature.

Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.

Molecular Characterization and Pathogenesis of Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.

The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.

Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections.

Targeting Aggressive Pituitary Adenomas at the Molecular Level-A Review.

Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS.

Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification.

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.

Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT-20 and TtT/GF by affecting expression of MMP-14 and ADAM12.

Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling.

Familial Pancreatic Cancer.