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1.

Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary.

Pouyiourou, Maria; Bochtler, Tilmann; Coith, Cornelia; Wikman, Harriet; Kraft, Bianca; Hielscher, Thomas; Stenzinger, Albrecht; Riethdorf, Sabine; Pantel, Klaus; Krämer, Alwin.

Clin Chem ; 70(1): 297-306, 2024 01 04.

Article in English | MEDLINE | ID: mdl-38175594

2.

Prognostic impact of copy number alterations and tumor mutational burden in carcinoma of unknown primary.

Bochtler, Tilmann; Wohlfromm, Timothy; Hielscher, Thomas; Stichel, Damian; Pouyiourou, Maria; Kraft, Bianca; Neumann, Olaf; Endris, Volker; von Deimling, Andreas; Stenzinger, Albrecht; Krämer, Alwin.

Genes Chromosomes Cancer ; 61(9): 551-560, 2022 09.

Article in English | MEDLINE | ID: mdl-35430765

3.

A Challenging Task: Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guidelines: The CUPISCO Trial Experience.

Pauli, Chantal; Bochtler, Tilmann; Mileshkin, Linda; Baciarello, Giulia; Losa, Ferran; Ross, Jeffrey S; Pentheroudakis, George; Zarkavelis, George; Yalcin, Suayib; Özgüroglu, Mustafa; Beringer, Andreas; Scarato, Jeremy; Mueller-Ohldach, Mathis; Thomas, Marlene; Moch, Holger; Krämer, Alwin.

Oncologist ; 26(5): e769-e779, 2021 05.

Article in English | MEDLINE | ID: mdl-33687747

4.

Cryostorage to What End? - Autologous Stem Cell Products in Burkitt Lymphoma, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Myeloproliferative Neoplasm Patients.

Kriegsmann, Katharina; Pavel, Petra; Bochtler, Tilmann; Schmitt, Anita; Sauer, Sandra; Kriegsmann, Mark; Bruckner, Thomas; Klein, Stefan; Klüter, Harald; Müller-Tidow, Carsten; Wuchter, Patrick.

Transfus Med Hemother ; 48(2): 91-98, 2021 Mar.

Article in English | MEDLINE | ID: mdl-33976609

5.

Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary.

Bochtler, Tilmann; Reiling, Anna; Endris, Volker; Hielscher, Thomas; Volckmar, Anna-Lena; Neumann, Olaf; Kirchner, Martina; Budczies, Jan; Heukamp, Lukas C; Leichsenring, Jonas; Allgäuer, Michael; Kazdal, Daniel; Löffler, Harald; Weichert, Wilko; Schirmacher, Peter; Stenzinger, Albrecht; Krämer, Alwin.

Int J Cancer ; 146(11): 3053-3064, 2020 06 01.

Article in English | MEDLINE | ID: mdl-31970771

6.

Micronucleus formation in human cancer cells is biased by chromosome size.

Bochtler, Tilmann; Kartal-Kaess, Mutlu; Granzow, Martin; Hielscher, Thomas; Cosenza, Marco R; Herold-Mende, Christel; Jauch, Anna; Krämer, Alwin.

Genes Chromosomes Cancer ; 58(6): 392-395, 2019 06.

Article in English | MEDLINE | ID: mdl-30411433

7.

Comparative genetic profiling aids diagnosis and clinical decision making in challenging cases of CUP syndrome.

Bochtler, Tilmann; Endris, Volker; Leichsenring, Jonas; Reiling, Anna; Neumann, Olaf; Volckmar, Anna-Lena; Kirchner, Martina; Allgäuer, Michael; Schirmacher, Peter; Krämer, Alwin; Stenzinger, Albrecht.

Int J Cancer ; 145(11): 2963-2973, 2019 12 01.

Article in English | MEDLINE | ID: mdl-30963573

8.

AL amyloidosis patients with low amyloidogenic free light chain levels at first diagnosis have an excellent prognosis.

Dittrich, Tobias; Bochtler, Tilmann; Kimmich, Christoph; Becker, Natalia; Jauch, Anna; Goldschmidt, Hartmut; Ho, Anthony D; Hegenbart, Ute; Schönland, Stefan O.

Blood ; 130(5): 632-642, 2017 08 03.

Article in English | MEDLINE | ID: mdl-28550043

9.

Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia.

Bochtler, Tilmann; Granzow, Martin; Stölzel, Friedrich; Kunz, Christina; Mohr, Brigitte; Kartal-Kaess, Mutlu; Hinderhofer, Katrin; Heilig, Christoph E; Kramer, Michael; Thiede, Christian; Endris, Volker; Kirchner, Martina; Stenzinger, Albrecht; Benner, Axel; Bornhäuser, Martin; Ehninger, Gerhard; Ho, Anthony D; Jauch, Anna; Krämer, Alwin.

Blood ; 129(10): 1333-1342, 2017 03 09.

Article in English | MEDLINE | ID: mdl-28119329

10.

Performance analysis of AL amyloidosis cardiac biomarker staging systems with special focus on renal failure and atrial arrhythmia.

Dittrich, Tobias; Benner, Axel; Kimmich, Christoph; Siepen, Fabian Aus dem; Veelken, Kaya; Kristen, Arnt V; Bochtler, Tilmann; Katus, Hugo A; Müller-Tidow, Carsten; Hegenbart, Ute; Schönland, Stefan O.

Haematologica ; 104(7): 1451-1459, 2019 07.

Article in English | MEDLINE | ID: mdl-30655373

11.

Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial.

Platzbecker, Uwe; Middeke, Jan Moritz; Sockel, Katja; Herbst, Regina; Wolf, Dominik; Baldus, Claudia D; Oelschlägel, Uta; Mütherig, Anke; Fransecky, Lars; Noppeney, Richard; Bug, Gesine; Götze, Katharina S; Krämer, Alwin; Bochtler, Tilmann; Stelljes, Matthias; Groth, Christoph; Schubert, Antje; Mende, Marika; Stölzel, Friedrich; Borkmann, Christine; Kubasch, Anne Sophie; von Bonin, Malte; Serve, Hubert; Hänel, Mathias; Dührsen, Ulrich; Schetelig, Johannes; Röllig, Christoph; Kramer, Michael; Ehninger, Gerhard; Bornhäuser, Martin; Thiede, Christian.

Lancet Oncol ; 19(12): 1668-1679, 2018 12.

Article in English | MEDLINE | ID: mdl-30442503

12.

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study.

Bochtler, Tilmann; Hegenbart, Ute; Kunz, Christina; Benner, Axel; Kimmich, Christoph; Seckinger, Anja; Hose, Dirk; Goldschmidt, Hartmut; Granzow, Martin; Dreger, Peter; Ho, Anthony D; Jauch, Anna; Schönland, Stefan O.

Blood ; 128(4): 594-602, 2016 07 28.

Article in English | MEDLINE | ID: mdl-27257181

13.

Integrated Histogenetic Analysis Reveals BAP1-Mutated Epithelioid Mesothelioma in a Patient With Cancer of Unknown Primary.

Bochtler, Tilmann; Endris, Volker; Reiling, Anna; Leichsenring, Jonas; Schweiger, Michal R; Klein, Sebastian; Stögbauer, Fabian; Goeppert, Benjamin; Schirmacher, Peter; Krämer, Alwin; Stenzinger, Albrecht.

J Natl Compr Canc Netw ; 16(6): 677-682, 2018 06.

Article in English | MEDLINE | ID: mdl-29891518

14.

Enasidenib.

Krämer, Alwin; Bochtler, Tilmann.

Recent Results Cancer Res ; 212: 187-197, 2018.

Article in English | MEDLINE | ID: mdl-30069631

15.

Diagnosis and management of metastatic neoplasms with unknown primary.

Bochtler, Tilmann; Löffler, Harald; Krämer, Alwin.

Semin Diagn Pathol ; 35(3): 199-206, 2018 May.

Article in English | MEDLINE | ID: mdl-29203116

16.

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis.

Granzow, Martin; Hegenbart, Ute; Hinderhofer, Katrin; Hose, Dirk; Seckinger, Anja; Bochtler, Tilmann; Hemminki, Kari; Goldschmidt, Hartmut; Schönland, Stefan O; Jauch, Anna.

Haematologica ; 102(7): 1281-1290, 2017 07.

Article in English | MEDLINE | ID: mdl-28341732

17.

Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia.

Wang, Wenwen; Stiehl, Thomas; Raffel, Simon; Hoang, Van T; Hoffmann, Isabel; Poisa-Beiro, Laura; Saeed, Borhan R; Blume, Rachel; Manta, Linda; Eckstein, Volker; Bochtler, Tilmann; Wuchter, Patrick; Essers, Marieke; Jauch, Anna; Trumpp, Andreas; Marciniak-Czochra, Anna; Ho, Anthony D; Lutz, Christoph.

Haematologica ; 102(9): 1567-1577, 2017 09.

Article in English | MEDLINE | ID: mdl-28550184

18.

Lenalidomide/melphalan/dexamethasone in newly diagnosed patients with immunoglobulin light chain amyloidosis: results of a prospective phase 2 study with long-term follow up.

Hegenbart, Ute; Bochtler, Tilmann; Benner, Axel; Becker, Natalia; Kimmich, Christoph; Kristen, Arnt V; Beimler, Jörg; Hund, Ernst; Zorn, Markus; Freiberger, Anja; Gawlik, Marianne; Goldschmidt, Hartmut; Hose, Dirk; Jauch, Anna; Ho, Anthony D; Schönland, Stefan O.

Haematologica ; 102(8): 1424-1431, 2017 08.

Article in English | MEDLINE | ID: mdl-28522573

19.

Mesenchymal stromal cells contribute to quiescence of therapy-resistant leukemic cells in acute myeloid leukemia.

Wang, Wenwen; Bochtler, Tilmann; Wuchter, Patrick; Manta, Linda; He, Haiju; Eckstein, Volker; Ho, Anthony D; Lutz, Christoph.

Eur J Haematol ; 99(5): 392-398, 2017 Nov.

Article in English | MEDLINE | ID: mdl-28800175

20.

Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD.

Ho, Anthony D; Schetelig, Johannes; Bochtler, Tilmann; Schaich, Markus; Schäfer-Eckart, Kerstin; Hänel, Mathias; Rösler, Wolf; Einsele, Hermann; Kaufmann, Martin; Serve, Hubert; Berdel, Wolfgang E; Stelljes, Matthias; Mayer, Jiri; Reichle, Albrecht; Baldus, Claudia D; Schmitz, Norbert; Kramer, Michael; Röllig, Christoph; Bornhäuser, Martin; Thiede, Christian; Ehninger, Gerhard.

Biol Blood Marrow Transplant ; 22(3): 462-9, 2016 Mar.

Article in English | MEDLINE | ID: mdl-26551637

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