Search | VHL Search Portal

1.

Juneteenth in STEMM and the barriers to equitable science.

Mays, Alfred; Byars-Winston, Angela; Hinton, Antentor; Marshall, Andrea G; Kirabo, Annet; August, Avery; Marlin, Bianca J; Riggs, Blake; Tolbert, Blanton; Wanjalla, Celestine; Womack, Chad; Evans, Chantell S; Barnes, Christopher; Starbird, Chrystal; Williams, Clintoria; Reynolds, Corey; Taabazuing, Cornelius; Cameron, Craig E; Murray, Debra D; Applewhite, Derek; Morton, Derrick J; Lee, Dexter; Williams, Dionna W; Lynch, Donald; Brady, Donita; Lynch, Erin; Rutaganira, Florentine U N; Silva, Gustavo M; Shuler, Haysetta; Saboor, Ishmail Abdus; Davis, Jamaine; Dzirasa, Kafui; Hammonds-Odie, Latanya; Reyes, Loretta; Sweetwyne, Mariya T; McReynolds, Melanie R; Johnson, Michael D L; Smith, Nathan A; Pittman, Nikea; Ajijola, Olujimi A; Smith, Quinton; Robinson, Renã A S; Lewis, Samantha C; Murray, Sandra A; Black, Sherilynn; Neal, Sonya E; Andrisse, Stanley; Townsend, Steven; Damo, Steven M; Griffith, Theanne N.

Cell ; 186(12): 2510-2517, 2023 06 08.

Article in English | MEDLINE | ID: mdl-37295396

2.

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death.

Cobine, Paul A; Brady, Donita C.

Mol Cell ; 82(10): 1786-1787, 2022 05 19.

Article in English | MEDLINE | ID: mdl-35594843

3.

RASopathy mutations open new insights into the mechanism of BRAF activation.

Dar, Arvin C; Brady, Donita C.

Mol Cell ; 82(22): 4192-4193, 2022 11 17.

Article in English | MEDLINE | ID: mdl-36400004

4.

Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools.

Pezacki, Aidan T; Matier, Carson D; Gu, Xingxing; Kummelstedt, Eric; Bond, Sarah E; Torrente, Laura; Jordan-Sciutto, Kelly L; DeNicola, Gina M; Su, Timothy A; Brady, Donita C; Chang, Christopher J.

Proc Natl Acad Sci U S A ; 119(43): e2202736119, 2022 10 25.

Article in English | MEDLINE | ID: mdl-36252013

5.

Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species.

Doan, Mary T; Neinast, Michael D; Varner, Erika L; Bedi, Kenneth C; Bartee, David; Jiang, Helen; Trefely, Sophie; Xu, Peining; Singh, Jay P; Jang, Cholsoon; Rame, J Eduardo; Brady, Donita C; Meier, Jordan L; Marguiles, Kenneth B; Arany, Zoltan; Snyder, Nathaniel W.

J Lipid Res ; 63(6): 100224, 2022 06.

Article in English | MEDLINE | ID: mdl-35568254

6.

The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.

Grasso, Michael; Bond, Gavin J; Kim, Ye-Jin; Boyd, Stefanie; Matson Dzebo, Maria; Valenzuela, Sebastian; Tsang, Tiffany; Schibrowsky, Natalie A; Alwan, Katherine B; Blackburn, Ninian J; Burslem, George M; Wittung-Stafshede, Pernilla; Winkler, Duane D; Marmorstein, Ronen; Brady, Donita C.

J Biol Chem ; 297(6): 101314, 2021 12.

Article in English | MEDLINE | ID: mdl-34715128

7.

Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism.

Chung, Clive Yik-Sham; Posimo, Jessica M; Lee, Sumin; Tsang, Tiffany; Davis, Julianne M; Brady, Donita C; Chang, Christopher J.

Proc Natl Acad Sci U S A ; 116(37): 18285-18294, 2019 09 10.

Article in English | MEDLINE | ID: mdl-31451653

8.

Capturing copper to inhibit inflammation.

Chang, Christopher J; Brady, Donita C.

Nat Chem Biol ; 19(8): 937-939, 2023 08.

Article in English | MEDLINE | ID: mdl-37443394

9.

Copper is required for oncogenic BRAF signalling and tumorigenesis.

Brady, Donita C; Crowe, Matthew S; Turski, Michelle L; Hobbs, G Aaron; Yao, Xiaojie; Chaikuad, Apirat; Knapp, Stefan; Xiao, Kunhong; Campbell, Sharon L; Thiele, Dennis J; Counter, Christopher M.

Nature ; 509(7501): 492-6, 2014 May 22.

Article in English | MEDLINE | ID: mdl-24717435

10.

IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B.

Parham, Louis R; Williams, Patrick A; Katada, Kay; Nettleford, Shaneice K; Chatterji, Priya; Acheampong, Kofi K; Danan, Charles H; Ma, Xianghui; Simon, Lauren A; Naughton, Kaitlyn E; Mizuno, Rei; Karakasheva, Tatiana; McMillan, Emily A; Whelan, Kelly A; Brady, Donita C; Shaffer, Sydney M; Hamilton, Kathryn E.

Cell Mol Gastroenterol Hepatol ; 17(3): 439-451, 2024.

Article in English | MEDLINE | ID: mdl-38081361

11.

Understanding and drugging RAS: 40âyears to break the tip of the iceberg.

Brady, Donita C; Hmeljak, Julija; Dar, Arvin C.

Dis Model Mech ; 15(2)2022 02 01.

Article in English | MEDLINE | ID: mdl-35244677

12.

BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing.

Tsang, Tiffany; Gu, Xingxing; Davis, Caroline I; Posimo, Jessica M; Miller, Zoey A; Brady, Donita C.

Mol Cancer Res ; 20(7): 1096-1107, 2022 07 06.

Article in English | MEDLINE | ID: mdl-35320362

13.

Copper Modulates the Catalytic Activity of Protein Kinase CK2.

Chojnowski, John E; Li, Rongrong; Tsang, Tiffany; Alfaran, Fatimah H; Dick, Alexej; Cocklin, Simon; Brady, Donita C; Strochlic, Todd I.

Front Mol Biosci ; 9: 878652, 2022.

Article in English | MEDLINE | ID: mdl-35755824

14.

Loss of p19Arf promotes fibroblast survival during leucine deprivation.

Roby, Kerry C; Lieberman, Allyson; Kim, Bang-Jin; Rodríguez, Nicole Zaragoza; Posimo, Jessica M; Tsang, Tiffany; Verginadis, Ioannis I; Puré, Ellen; Brady, Donita C; Koumenis, Constantinos; Ryeom, Sandra.

Biol Open ; 11(2)2022 02 15.

Article in English | MEDLINE | ID: mdl-34994382

15.

The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17.

Chaves-Moreira, Daniele; Mitchell, Marilyn A; Arruza, Cristina; Rawat, Priyanka; Sidoli, Simone; Nameki, Robbin; Reddy, Jessica; Corona, Rosario I; Afeyan, Lena K; Klein, Isaac A; Ma, Sisi; Winterhoff, Boris; Konecny, Gottfried E; Garcia, Benjamin A; Brady, Donita C; Lawrenson, Kate; Morin, Patrice J; Drapkin, Ronny.

Sci Signal ; 15(728): eabm2496, 2022 04 05.

Article in English | MEDLINE | ID: mdl-35380877

16.

Connecting copper and cancer: from transition metal signalling to metalloplasia.

Ge, Eva J; Bush, Ashley I; Casini, Angela; Cobine, Paul A; Cross, Justin R; DeNicola, Gina M; Dou, Q Ping; Franz, Katherine J; Gohil, Vishal M; Gupta, Sanjeev; Kaler, Stephen G; Lutsenko, Svetlana; Mittal, Vivek; Petris, Michael J; Polishchuk, Roman; Ralle, Martina; Schilsky, Michael L; Tonks, Nicholas K; Vahdat, Linda T; Van Aelst, Linda; Xi, Dan; Yuan, Peng; Brady, Donita C; Chang, Christopher J.

Nat Rev Cancer ; 22(2): 102-113, 2022 02.

Article in English | MEDLINE | ID: mdl-34764459

17.

Copper biology.

Tsang, Tiffany; Davis, Caroline I; Brady, Donita C.

Curr Biol ; 31(9): R421-R427, 2021 05 10.

Article in English | MEDLINE | ID: mdl-33974864

18.

Academic careers and the COVID-19 pandemic: Reversing the tide.

Carr, Rotonya M; Lane-Fall, Meghan B; South, Eugenia; Brady, Donita; Momplaisir, Florence; Guerra, Carmen E; Montoya-Williams, Diana; Dalembert, George; Lavizzo-Mourey, Risa; Hamilton, Roy.

Sci Transl Med ; 13(584)2021 03 10.

Article in English | MEDLINE | ID: mdl-33692133

19.

Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation.

Madigan, James P; Bodemann, Brian O; Brady, Donita C; Dewar, Brian J; Keller, Patricia J; Leitges, Michael; Philips, Mark R; Ridley, Anne J; Der, Channing J; Cox, Adrienne D.

Biochem J ; 424(1): 153-61, 2009 Oct 23.

Article in English | MEDLINE | ID: mdl-19723022

20.

The Race toward Equity: Increasing Racial Diversity in Cancer Research and Cancer Care.

Brady, Donita C; Weeraratna, Ashani T.

Cancer Discov ; 10(10): 1451-1454, 2020 10.

Article in English | MEDLINE | ID: mdl-32816861

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: