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1.
A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.
Nucleic Acids Res
; 2024 May 10.
Article
in English
| MEDLINE | ID: mdl-38726879
2.
mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo.
bioRxiv
; 2024 Apr 28.
Article
in English
| MEDLINE | ID: mdl-38774633
3.
Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.
Elife
; 122024 Apr 02.
Article
in English
| MEDLINE | ID: mdl-38564479
4.
Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation.
bioRxiv
; 2024 Jun 08.
Article
in English
| MEDLINE | ID: mdl-38895198
5.
Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.
bioRxiv
; 2023 Jul 05.
Article
in English
| MEDLINE | ID: mdl-37461560
6.
A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system.
bioRxiv
; 2023 Dec 19.
Article
in English
| MEDLINE | ID: mdl-38187561
7.
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
Res Sq
; 2023 Jun 01.
Article
in English
| MEDLINE | ID: mdl-37398145
8.
Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.
bioRxiv
; 2023 Oct 19.
Article
in English
| MEDLINE | ID: mdl-37205462
9.
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
bioRxiv
; 2023 May 26.
Article
in English
| MEDLINE | ID: mdl-37292886
10.
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Nat Commun
; 14(1): 7099, 2023 11 04.
Article
in English
| MEDLINE | ID: mdl-37925520
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