Search details
1.
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Cell
; 165(1): 111-124, 2016 Mar 24.
Article
in English
| MEDLINE | ID: mdl-26972052
2.
Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis.
Cell
; 163(7): 1585-95, 2015 Dec 17.
Article
in English
| MEDLINE | ID: mdl-26687352
3.
Gut Microbiota-Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms.
Circulation
; 147(14): 1079-1096, 2023 04 04.
Article
in English
| MEDLINE | ID: mdl-37011073
4.
Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
Eur Heart J
; 44(32): 3085-3096, 2023 08 22.
Article
in English
| MEDLINE | ID: mdl-37342006
5.
Site-specific 5-hydroxytryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high-density lipoprotein biogenesis.
J Biol Chem
; 295(15): 4836-4848, 2020 04 10.
Article
in English
| MEDLINE | ID: mdl-32098873
6.
Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease.
Arterioscler Thromb Vasc Biol
; 40(5): 1239-1255, 2020 05.
Article
in English
| MEDLINE | ID: mdl-32212854
7.
Small molecule inhibition of gut microbial choline trimethylamine lyase activity alters host cholesterol and bile acid metabolism.
Am J Physiol Heart Circ Physiol
; 318(6): H1474-H1486, 2020 06 01.
Article
in English
| MEDLINE | ID: mdl-32330092
8.
A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein.
J Biol Chem
; 291(12): 6386-95, 2016 Mar 18.
Article
in English
| MEDLINE | ID: mdl-26797122
9.
Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.
Circ Res
; 116(3): 448-55, 2015 Jan 30.
Article
in English
| MEDLINE | ID: mdl-25599331
10.
Transmission of atherosclerosis susceptibility with gut microbial transplantation.
J Biol Chem
; 290(9): 5647-60, 2015 Feb 27.
Article
in English
| MEDLINE | ID: mdl-25550161
11.
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide.
Eur Heart J
; 35(14): 904-10, 2014 Apr.
Article
in English
| MEDLINE | ID: mdl-24497336
12.
2H2O-based high-density lipoprotein turnover method for the assessment of dynamic high-density lipoprotein function in mice.
Arterioscler Thromb Vasc Biol
; 33(8): 1994-2003, 2013 Aug.
Article
in English
| MEDLINE | ID: mdl-23766259
13.
Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models.
mBio
; 14(5): e0093723, 2023 Oct 31.
Article
in English
| MEDLINE | ID: mdl-37737636
14.
Two distinct gut microbial pathways contribute to meta-organismal production of phenylacetylglutamine with links to cardiovascular disease.
Cell Host Microbe
; 31(1): 18-32.e9, 2023 01 11.
Article
in English
| MEDLINE | ID: mdl-36549300
15.
Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure.
Circ Heart Fail
; 16(1): e009972, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36524472
16.
Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis.
Cardiovasc Res
; 118(10): 2367-2384, 2022 07 27.
Article
in English
| MEDLINE | ID: mdl-34352109
17.
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
Elife
; 112022 01 24.
Article
in English
| MEDLINE | ID: mdl-35072627
18.
The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism.
Nat Microbiol
; 7(1): 73-86, 2022 01.
Article
in English
| MEDLINE | ID: mdl-34949826
19.
Gut microbes impact stroke severity via the trimethylamine N-oxide pathway.
Cell Host Microbe
; 29(7): 1199-1208.e5, 2021 07 14.
Article
in English
| MEDLINE | ID: mdl-34139173
20.
Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.
Nat Med
; 24(9): 1407-1417, 2018 09.
Article
in English
| MEDLINE | ID: mdl-30082863