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1.
NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations.
Nat Immunol
; 17(10): 1176-86, 2016 10.
Article
in English
| MEDLINE | ID: mdl-27548431
2.
Fecal-adherent mucus is a non-invasive source of primary human MUC2 for structural and functional characterization in health and disease.
J Biol Chem
; 300(3): 105675, 2024 Mar.
Article
in English
| MEDLINE | ID: mdl-38272223
3.
Unfermented ß-fructan Fibers Fuel Inflammation in Select Inflammatory Bowel Disease Patients.
Gastroenterology
; 164(2): 228-240, 2023 02.
Article
in English
| MEDLINE | ID: mdl-36183751
4.
The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1ß secretion.
PLoS Pathog
; 18(3): e1010415, 2022 03.
Article
in English
| MEDLINE | ID: mdl-35303042
5.
Entamoeba histolytica activation of caspase-1 degrades cullin that attenuates NF-κB dependent signaling from macrophages.
PLoS Pathog
; 17(9): e1009936, 2021 09.
Article
in English
| MEDLINE | ID: mdl-34499701
6.
Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress.
Am J Physiol Gastrointest Liver Physiol
; 321(5): G489-G499, 2021 11 01.
Article
in English
| MEDLINE | ID: mdl-34494458
7.
Defining cooperative roles for colonic microbiota and Muc2 mucin in mediating innate host defense against Entamoeba histolytica.
PLoS Pathog
; 14(11): e1007466, 2018 11.
Article
in English
| MEDLINE | ID: mdl-30500860
8.
Entamoeba histolytica Interaction with Enteropathogenic Escherichia coli Increases Parasite Virulence and Inflammation in Amebiasis.
Infect Immun
; 87(12)2019 12.
Article
in English
| MEDLINE | ID: mdl-31527129
9.
Functional Characterization of an Interferon Gamma Receptor-Like Protein on Entamoeba histolytica.
Infect Immun
; 87(11)2019 11.
Article
in English
| MEDLINE | ID: mdl-31427448
10.
The macrophage cytoskeleton acts as a contact sensor upon interaction with Entamoeba histolytica to trigger IL-1ß secretion.
PLoS Pathog
; 13(8): e1006592, 2017 Aug.
Article
in English
| MEDLINE | ID: mdl-28837696
11.
High MUC2 Mucin Biosynthesis in Goblet Cells Impedes Restitution and Wound Healing by Elevating Endoplasmic Reticulum Stress and Altered Production of Growth Factors.
Am J Pathol
; 188(9): 2025-2041, 2018 09.
Article
in English
| MEDLINE | ID: mdl-29935164
12.
High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells.
Am J Pathol
; 188(6): 1354-1373, 2018 06.
Article
in English
| MEDLINE | ID: mdl-29545196
13.
Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency.
Infect Immun
; 86(7)2018 07.
Article
in English
| MEDLINE | ID: mdl-29685982
14.
Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvß3 Integrin.
PLoS Pathog
; 12(4): e1005579, 2016 Apr.
Article
in English
| MEDLINE | ID: mdl-27073869
15.
Cysteine Protease-Dependent Mucous Disruptions and Differential Mucin Gene Expression in Giardia duodenalis Infection.
Am J Pathol
; 187(11): 2486-2498, 2017 Nov.
Article
in English
| MEDLINE | ID: mdl-28823873
16.
MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis.
Infect Immun
; 85(3)2017 03.
Article
in English
| MEDLINE | ID: mdl-28069814
17.
Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice.
Am J Physiol Gastrointest Liver Physiol
; 312(1): G34-G45, 2017 01 01.
Article
in English
| MEDLINE | ID: mdl-27856417
18.
The NLRP3 Inflammasome Is a Pathogen Sensor for Invasive Entamoeba histolytica via Activation of α5ß1 Integrin at the Macrophage-Amebae Intercellular Junction.
PLoS Pathog
; 11(5): e1004887, 2015 May.
Article
in English
| MEDLINE | ID: mdl-25955828
19.
Entamoeba histolytica exacerbates epithelial tight junction permeability and proinflammatory responses in Muc2(-/-) mice.
Am J Pathol
; 182(3): 852-65, 2013 Mar.
Article
in English
| MEDLINE | ID: mdl-23357502
20.
Correction for Cobo et al., "Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency".
Infect Immun
; 86(10)2018 10.
Article
in English
| MEDLINE | ID: mdl-30242014