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1.
Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial-Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis.
Int J Mol Sci
; 23(21)2022 Nov 01.
Article
in English
| MEDLINE | ID: mdl-36362141
2.
Reverse engineering a predictive signature characterized by proliferation, DNA damage, and immune escape from stage I lung adenocarcinoma recurrence.
Acta Biochim Biophys Sin (Shanghai)
; 52(6): 638-653, 2020 Jun 20.
Article
in English
| MEDLINE | ID: mdl-32395755
3.
Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.
Int J Cancer
; 143(5): 1162-1175, 2018 09 01.
Article
in English
| MEDLINE | ID: mdl-29577277
4.
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.
Mol Cancer
; 16(1): 30, 2017 02 01.
Article
in English
| MEDLINE | ID: mdl-28148261
5.
Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury.
Stem Cells
; 32(3): 822-7, 2014 Mar.
Article
in English
| MEDLINE | ID: mdl-24123696
6.
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
Mol Cancer
; 13: 103, 2014 May 06.
Article
in English
| MEDLINE | ID: mdl-24885928
7.
Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.
Am J Physiol Gastrointest Liver Physiol
; 306(5): G404-11, 2014 Mar 01.
Article
in English
| MEDLINE | ID: mdl-24368703
8.
Evidence of functional cross talk between the Notch and NF-κB pathways in nonneoplastic hyperproliferating colonic epithelium.
Am J Physiol Gastrointest Liver Physiol
; 304(4): G356-70, 2013 Feb 15.
Article
in English
| MEDLINE | ID: mdl-23203159
9.
Critical roles of Notch and Wnt/ß-catenin pathways in the regulation of hyperplasia and/or colitis in response to bacterial infection.
Infect Immun
; 80(9): 3107-21, 2012 Sep.
Article
in English
| MEDLINE | ID: mdl-22710872
10.
Distinct compartmentalization of NF-κB activity in crypt and crypt-denuded lamina propria precedes and accompanies hyperplasia and/or colitis following bacterial infection.
Infect Immun
; 80(2): 753-67, 2012 Feb.
Article
in English
| MEDLINE | ID: mdl-22144489
11.
Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38.
J Biol Chem
; 285(43): 33485-33498, 2010 Oct 22.
Article
in English
| MEDLINE | ID: mdl-20710027
12.
Inflammatory Mediators and Gut Microbial Toxins Drive Colon Tumorigenesis by IL-23 Dependent Mechanism.
Cancers (Basel)
; 13(20)2021 Oct 14.
Article
in English
| MEDLINE | ID: mdl-34680308
13.
Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment.
Cancers (Basel)
; 12(12)2020 Dec 17.
Article
in English
| MEDLINE | ID: mdl-33348546
14.
Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases.
J Inflamm Res
; 13: 1261-1278, 2020.
Article
in English
| MEDLINE | ID: mdl-33408499
15.
Tamoxifen induces stem-like phenotypes and multidrug resistance by altering epigenetic regulators in ERα+ breast cancer cells.
Stem Cell Investig
; 7: 20, 2020.
Article
in English
| MEDLINE | ID: mdl-33294429
16.
DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.
Mol Cancer Ther
; 19(7): 1539-1549, 2020 07.
Article
in English
| MEDLINE | ID: mdl-32371580
17.
Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism.
Sci Rep
; 10(1): 10578, 2020 06 29.
Article
in English
| MEDLINE | ID: mdl-32601309
18.
DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4.
Mol Ther Oncolytics
; 18: 24-36, 2020 Sep 25.
Article
in English
| MEDLINE | ID: mdl-32637578
19.
Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma.
Biomark Res
; 7: 5, 2019.
Article
in English
| MEDLINE | ID: mdl-30899515
20.
Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer.
J Oncol
; 2019: 6402925, 2019.
Article
in English
| MEDLINE | ID: mdl-31467540