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1.

Critical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury.

Lin, Hugo Y-H; Liang, Chan-Jung; Yang, Ming-Yu; Chen, Phang-Lang; Wang, Tzu-Ming; Chen, Yen-Hua; Shih, Yao-Hsiang; Liu, Wangta; Chiu, Chien-Chih; Chiang, Chih-Kang; Lin, Chang-Shen; Lin, Han-Chen.

Apoptosis ; 29(5-6): 620-634, 2024 Jun.

Article in English | MEDLINE | ID: mdl-38281282

2.

The Link between Autosomal Dominant Polycystic Kidney Disease and Chromosomal Instability: Exploring the Relationship.

Chen, Phang-Lang; Chen, Chi-Fen; Lin, Hugo Y-H; Riley, Daniel J; Chen, Yumay.

Int J Mol Sci ; 25(5)2024 Mar 02.

Article in English | MEDLINE | ID: mdl-38474184

3.

Mitochondrial Signaling, the Mechanisms of AKI-to-CKD Transition and Potential Treatment Targets.

Chang, Li-Yun; Chao, Yu-Lin; Chiu, Chien-Chih; Chen, Phang-Lang; Lin, Hugo Y-H.

Int J Mol Sci ; 25(3)2024 Jan 26.

Article in English | MEDLINE | ID: mdl-38338797

4.

Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism.

Chen, Yu-Han; Ta, Albert P; Chen, Yumay; Lee, Hsiao-Chen; Fan, Wenjun; Chen, Phang-Lang; Jordan, Maria C; Roos, Kenneth P; MacGregor, Grant R; Yang, Qin; Edwards, Robert A; Li, Junfeng; Wang, Ping H.

Cardiovasc Diabetol ; 22(1): 294, 2023 10 27.

Article in English | MEDLINE | ID: mdl-37891673

5.

High risk of renal outcome of metabolic syndrome independent of diabetes in patients with CKD stage 1-4: The ICKD database.

Lin, Hugo Y-H; Chang, Li-Yun; Niu, Sheng-Wen; Kuo, I-Ching; Yen, Chia-Hung; Shen, Feng-Ching; Chen, Phang-Lang; Chang, Jer-Ming; Hung, Chi-Chih.

Diabetes Metab Res Rev ; 39(4): e3618, 2023 05.

Article in English | MEDLINE | ID: mdl-36731513

6.

SUV3 Helicase and Mitochondrial Homeostasis.

Chen, Phang-Lang.

Int J Mol Sci ; 24(11)2023 May 25.

Article in English | MEDLINE | ID: mdl-37298184

7.

BRCA1 the Versatile Defender: Molecular to Environmental Perspectives.

Zhong, Amy X; Chen, Yumay; Chen, Phang-Lang.

Int J Mol Sci ; 24(18)2023 Sep 19.

Article in English | MEDLINE | ID: mdl-37762577

8.

Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease.

Wei, Pei-Chi; Hsieh, Yi-Hsuan; Su, Mei-I; Jiang, Xianzhi; Hsu, Pang-Hung; Lo, Wen-Ting; Weng, Jui-Yun; Jeng, Yung-Ming; Wang, Ju-Ming; Chen, Phang-lang; Chang, Yi-Cheng; Lee, Kuo-Fen; Tsai, Ming-Daw; Shew, Jin-Yuh; Lee, Wen-Hwa.

Mol Cell ; 48(5): 747-59, 2012 Dec 14.

Article in English | MEDLINE | ID: mdl-23123197

9.

Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes.

Wang, Dennis Ding-Hwa; Guo, Xuning Emily; Modrek, Aram Sandaldjian; Chen, Chi-Fen; Chen, Phang-Lang; Lee, Wen-Hwa.

J Biol Chem ; 289(24): 16727-35, 2014 Jun 13.

Article in English | MEDLINE | ID: mdl-24770417

10.

Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.

Furuta, Saori; Wang, Ju-Ming; Wei, Shuanzeng; Jeng, Yung-Ming; Jiang, Xianzhi; Gu, Bingnan; Chen, Phang-Lang; Lee, Eva Y-H P; Lee, Wen-Hwa.

Cancer Cell ; 10(1): 13-24, 2006 Jul.

Article in English | MEDLINE | ID: mdl-16843262

11.

Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation.

Guo, Xuning Emily; Chen, Chi-Fen; Wang, Dennis Ding-Hwa; Modrek, Aram Sandaldjian; Phan, Vy Hoai; Lee, Wen-Hwa; Chen, Phang-Lang.

J Biol Chem ; 286(44): 38783-38794, 2011 Nov 04.

Article in English | MEDLINE | ID: mdl-21911497

12.

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability.

Chen, Yumay; Chen, Chi-Fen; Chiang, Huai-Chin; Pena, Michelle; Polci, Rosaria; Wei, Randy L; Edwards, Robert A; Hansel, Donna E; Chen, Phang-Lang; Riley, Daniel J.

Mol Cancer ; 10(1): 5, 2011 Jan 10.

Article in English | MEDLINE | ID: mdl-21214959

13.

Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality.

Wang, Dennis Ding-Hwa; Shu, Zhanyong; Lieser, Scot A; Chen, Phang-Lang; Lee, Wen-Hwa.

J Biol Chem ; 284(31): 20812-21, 2009 Jul 31.

Article in English | MEDLINE | ID: mdl-19509288

14.

Structural requirements of chromokinesin Kif4A for its proper function in mitosis.

Wu, Guikai; Chen, Phang-Lang.

Biochem Biophys Res Commun ; 372(3): 454-8, 2008 Aug 01.

Article in English | MEDLINE | ID: mdl-18502200

15.

Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37.

Tawara, Hideyuki; Fujiuchi, Nobuko; Sironi, Juan; Martin, Sarah; Aglipay, Jason; Ouchi, Mutsuko; Taga, Makoto; Chen, Phang-Lang; Ouchi, Toru.

Front Biosci ; 13: 240-8, 2008 Jan 01.

Article in English | MEDLINE | ID: mdl-17981542

16.

Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency.

Chen, Phang-Lang; Liu, Feng; Cai, Suna; Lin, Xiaoqin; Li, Aihua; Chen, Yumay; Gu, Bingnan; Lee, Eva Y-H P; Lee, Wen-Hwa.

Mol Cell Biol ; 25(9): 3535-42, 2005 May.

Article in English | MEDLINE | ID: mdl-15831459

17.

Aberrant DNA damage response and DNA repair pathway in high glucose conditions.

Zhong, Amy; Chang, Melissa; Yu, Theresa; Gau, Raymond; Riley, Daniel J; Chen, Yumay; Chen, Phang-Lang.

J Can Res Updates ; 7(3): 64-74, 2018.

Article in English | MEDLINE | ID: mdl-30498558

18.

NFBD1/Mdc1 mediates ATR-dependent DNA damage response.

Peng, Aimin; Chen, Phang-Lang.

Cancer Res ; 65(4): 1158-63, 2005 Feb 15.

Article in English | MEDLINE | ID: mdl-15734998

19.

NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response.

Polci, Rosaria; Peng, Aimin; Chen, Phang-Lang; Riley, Daniel J; Chen, Yumay.

Cancer Res ; 64(24): 8800-3, 2004 Dec 15.

Article in English | MEDLINE | ID: mdl-15604234

20.

Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability.

Zheng, Lei; Flesken-Nikitin, Andrea; Chen, Phang-Lang; Lee, Wen-Hwa.

Cancer Res ; 62(9): 2498-502, 2002 May 01.

Article in English | MEDLINE | ID: mdl-11980640

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