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1.

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.

Speir, Mary; Nowell, Cameron J; Chen, Alyce A; O'Donnell, Joanne A; Shamie, Isaac S; Lakin, Paul R; D'Cruz, Akshay A; Braun, Roman O; Babon, Jeff J; Lewis, Rowena S; Bliss-Moreau, Meghan; Shlomovitz, Inbar; Wang, Shu; Cengia, Louise H; Stoica, Anca I; Hakem, Razq; Kelliher, Michelle A; O'Reilly, Lorraine A; Patsiouras, Heather; Lawlor, Kate E; Weller, Edie; Lewis, Nathan E; Roberts, Andrew W; Gerlic, Motti; Croker, Ben A.

Nat Immunol ; 21(1): 54-64, 2020 01.

Article in English | MEDLINE | ID: mdl-31819256

2.

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

Rickard, James A; O'Donnell, Joanne A; Evans, Joseph M; Lalaoui, Najoua; Poh, Ashleigh R; Rogers, TeWhiti; Vince, James E; Lawlor, Kate E; Ninnis, Robert L; Anderton, Holly; Hall, Cathrine; Spall, Sukhdeep K; Phesse, Toby J; Abud, Helen E; Cengia, Louise H; Corbin, Jason; Mifsud, Sandra; Di Rago, Ladina; Metcalf, Donald; Ernst, Matthias; Dewson, Grant; Roberts, Andrew W; Alexander, Warren S; Murphy, James M; Ekert, Paul G; Masters, Seth L; Vaux, David L; Croker, Ben A; Gerlic, Motti; Silke, John.

Cell ; 157(5): 1175-88, 2014 May 22.

Article in English | MEDLINE | ID: mdl-24813849

3.

Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol.

Wang, Shaobo; Li, Wanyu; Hui, Hui; Tiwari, Shashi Kant; Zhang, Qiong; Croker, Ben A; Rawlings, Stephen; Smith, Davey; Carlin, Aaron F; Rana, Tariq M.

EMBO J ; 39(21): e106057, 2020 11 02.

Article in English | MEDLINE | ID: mdl-32944968

4.

Myelopoiesis embraces its inner weakness.

Gerlic, Motti; Croker, Ben A.

Nat Immunol ; 18(9): 953-954, 2017 08 22.

Article in English | MEDLINE | ID: mdl-28829446

5.

NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis.

Kaufmann, Benedikt; Leszczynska, Aleksandra; Reca, Agustina; Booshehri, Laela M; Onyuru, Janset; Tan, ZheHao; Wree, Alexander; Friess, Helmut; Hartmann, Daniel; Papouchado, Bettina; Broderick, Lori; Hoffman, Hal M; Croker, Ben A; Zhu, Yanfang Peipei; Feldstein, Ariel E.

EMBO Rep ; 23(11): e54446, 2022 11 07.

Article in English | MEDLINE | ID: mdl-36194627

6.

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.

Park, Sang Ho; Siddiqi, Haley; Castro, Daniela V; De Angelis, Anna A; Oom, Aaron L; Stoneham, Charlotte A; Lewinski, Mary K; Clark, Alex E; Croker, Ben A; Carlin, Aaron F; Guatelli, John; Opella, Stanley J.

PLoS Pathog ; 17(5): e1009519, 2021 05.

Article in English | MEDLINE | ID: mdl-34003853

7.

Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors.

Mor, Michael; Werbner, Michal; Alter, Joel; Safra, Modi; Chomsky, Elad; Lee, Jamie C; Hada-Neeman, Smadar; Polonsky, Ksenia; Nowell, Cameron J; Clark, Alex E; Roitburd-Berman, Anna; Ben-Shalom, Noam; Navon, Michal; Rafael, Dor; Sharim, Hila; Kiner, Evgeny; Griffis, Eric R; Gershoni, Jonathan M; Kobiler, Oren; Leibel, Sandra Lawrynowicz; Zimhony, Oren; Carlin, Aaron F; Yaari, Gur; Dessau, Moshe; Gal-Tanamy, Meital; Hagin, David; Croker, Ben A; Freund, Natalia T.

PLoS Pathog ; 17(2): e1009165, 2021 02.

Article in English | MEDLINE | ID: mdl-33571304

8.

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.

Berger, Michael; Krebs, Philippe; Crozat, Karine; Li, Xiaohong; Croker, Ben A; Siggs, Owen M; Popkin, Daniel; Du, Xin; Lawson, Brian R; Theofilopoulos, Argyrios N; Xia, Yu; Khovananth, Kevin; Moresco, Eva Marie; Satoh, Takashi; Takeuchi, Osamu; Akira, Shizuo; Beutler, Bruce.

Nat Immunol ; 11(4): 335-43, 2010 Apr.

Article in English | MEDLINE | ID: mdl-20190759

9.

ß-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment.

Pazhakh, Vahid; Ellett, Felix; Croker, Ben A; O'Donnell, Joanne A; Pase, Luke; Schulze, Keith E; Greulich, R Stefan; Gupta, Aakash; Reyes-Aldasoro, Constantino Carlos; Andrianopoulos, Alex; Lieschke, Graham J.

PLoS Biol ; 17(9): e3000113, 2019 09.

Article in English | MEDLINE | ID: mdl-31483778

10.

Inflammasome Activation in Children With Kawasaki Disease and Multisystem Inflammatory Syndrome.

Wang, Wei-Ting; He, Ming; Shimizu, Chisato; Croker, Ben A; Hoffman, Hal M; Tremoulet, Adriana H; Burns, Jane C; Shyy, John Y-J.

Arterioscler Thromb Vasc Biol ; 41(9): 2509-2511, 2021 09.

Article in English | MEDLINE | ID: mdl-34261329

11.

Walking down the memory lane with SARS-CoV-2 B cells.

Freund, Natalia T; Gerlic, Motti; Croker, Ben A.

Immunol Cell Biol ; 99(8): 796-799, 2021 09.

Article in English | MEDLINE | ID: mdl-34355822

12.

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.

Masters, Seth L; Gerlic, Motti; Metcalf, Donald; Preston, Simon; Pellegrini, Marc; O'Donnell, Joanne A; McArthur, Kate; Baldwin, Tracey M; Chevrier, Stephane; Nowell, Cameron J; Cengia, Louise H; Henley, Katya J; Collinge, Janelle E; Kastner, Daniel L; Feigenbaum, Lionel; Hilton, Douglas J; Alexander, Warren S; Kile, Benjamin T; Croker, Ben A.

Immunity ; 37(6): 1009-23, 2012 Dec 14.

Article in English | MEDLINE | ID: mdl-23219391

13.

NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis.

Kaufmann, Benedikt; Leszczynska, Aleksandra; Reca, Agustina; Booshehri, Laela M; Onyuru, Janset; Tan, ZheHao; Wree, Alexander; Friess, Helmut; Hartmann, Daniel; Papouchado, Bettina; Broderick, Lori; Hoffman, Hal M; Croker, Ben A; Zhu, Yanfang Peipei; Feldstein, Ariel E.

EMBO Rep ; 25(1): 455, 2024 Jan.

Article in English | MEDLINE | ID: mdl-38216786

14.

Phosphatidylserine externalization, "necroptotic bodies" release, and phagocytosis during necroptosis.

Zargarian, Sefi; Shlomovitz, Inbar; Erlich, Ziv; Hourizadeh, Aria; Ofir-Birin, Yifat; Croker, Ben A; Regev-Rudzki, Neta; Edry-Botzer, Liat; Gerlic, Motti.

PLoS Biol ; 15(6): e2002711, 2017 Jun.

Article in English | MEDLINE | ID: mdl-28650960

15.

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1ß Secretion.

Chen, Kaiwen W; Lawlor, Kate E; von Pein, Jessica B; Boucher, Dave; Gerlic, Motti; Croker, Ben A; Bezbradica, Jelena S; Vince, James E; Schroder, Kate.

J Immunol ; 200(10): 3341-3346, 2018 05 15.

Article in English | MEDLINE | ID: mdl-29661823

16.

A motive for killing: effector functions of regulated lytic cell death.

Bliss-Moreau, Meghan; Chen, Alyce A; D'Cruz, Akshay A; Croker, Ben A.

Immunol Cell Biol ; 95(2): 146-151, 2017 02.

Article in English | MEDLINE | ID: mdl-27826146

17.

Neutrophil survival in the death zone.

Croker, Ben A.

Blood ; 123(3): 307-8, 2014 Jan 16.

Article in English | MEDLINE | ID: mdl-24434994

18.

BID-ding on necroptosis in MDS.

Croker, Ben A; Kelliher, Michelle A.

Blood ; 133(2): 103-104, 2019 01 10.

Article in English | MEDLINE | ID: mdl-30630845

19.

Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis.

Croker, Ben A; Silke, John; Gerlic, Motti.

Curr Opin Hematol ; 22(4): 293-301, 2015 Jul.

Article in English | MEDLINE | ID: mdl-26049749

20.

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1.

Croker, Ben A; O'Donnell, Joanne A; Nowell, Cameron J; Metcalf, Donald; Dewson, Grant; Campbell, Kirsteen J; Rogers, Kelly L; Hu, Yifang; Smyth, Gordon K; Zhang, Jian-Guo; White, Michael; Lackovic, Kurt; Cengia, Louise H; O'Reilly, Lorraine A; Bouillet, Philippe; Cory, Suzanne; Strasser, Andreas; Roberts, Andrew W.

Proc Natl Acad Sci U S A ; 108(32): 13135-40, 2011 Aug 09.

Article in English | MEDLINE | ID: mdl-21768356

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Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol.

Myelopoiesis embraces its inner weakness.

NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis.

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.

Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors.

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.

ß-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment.

Inflammasome Activation in Children With Kawasaki Disease and Multisystem Inflammatory Syndrome.

Walking down the memory lane with SARS-CoV-2 B cells.

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.

NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis.

Phosphatidylserine externalization, "necroptotic bodies" release, and phagocytosis during necroptosis.

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1ß Secretion.

A motive for killing: effector functions of regulated lytic cell death.

Neutrophil survival in the death zone.

BID-ding on necroptosis in MDS.

Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis.

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1.