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1.

Propagation of Tau Aggregates and Neurodegeneration.

Goedert, Michel; Eisenberg, David S; Crowther, R Anthony.

Annu Rev Neurosci ; 40: 189-210, 2017 07 25.

Article in English | MEDLINE | ID: mdl-28772101

2.

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.

Falcon, Benjamin; Zivanov, Jasenko; Zhang, Wenjuan; Murzin, Alexey G; Garringer, Holly J; Vidal, Ruben; Crowther, R Anthony; Newell, Kathy L; Ghetti, Bernardino; Goedert, Michel; Scheres, Sjors H W.

Nature ; 568(7752): 420-423, 2019 04.

Article in English | MEDLINE | ID: mdl-30894745

3.

Structures of filaments from Pick's disease reveal a novel tau protein fold.

Falcon, Benjamin; Zhang, Wenjuan; Murzin, Alexey G; Murshudov, Garib; Garringer, Holly J; Vidal, Ruben; Crowther, R Anthony; Ghetti, Bernardino; Scheres, Sjors H W; Goedert, Michel.

Nature ; 561(7721): 137-140, 2018 09.

Article in English | MEDLINE | ID: mdl-30158706

4.

Cryo-EM structures of tau filaments from Alzheimer's disease.

Fitzpatrick, Anthony W P; Falcon, Benjamin; He, Shaoda; Murzin, Alexey G; Murshudov, Garib; Garringer, Holly J; Crowther, R Anthony; Ghetti, Bernardino; Goedert, Michel; Scheres, Sjors H W.

Nature ; 547(7662): 185-190, 2017 07 13.

Article in English | MEDLINE | ID: mdl-28678775

5.

Insights into neurodegeneration from electron microscopy studies.

Crowther, R Anthony.

Biochem Soc Trans ; 49(6): 2777-2786, 2021 12 17.

Article in English | MEDLINE | ID: mdl-34812894

6.

Brain homogenates from human tauopathies induce tau inclusions in mouse brain.

Clavaguera, Florence; Akatsu, Hiroyasu; Fraser, Graham; Crowther, R Anthony; Frank, Stephan; Hench, Jürgen; Probst, Alphonse; Winkler, David T; Reichwald, Julia; Staufenbiel, Matthias; Ghetti, Bernardino; Goedert, Michel; Tolnay, Markus.

Proc Natl Acad Sci U S A ; 110(23): 9535-40, 2013 Jun 04.

Article in English | MEDLINE | ID: mdl-23690619

7.

Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies.

Mellone, Manuela; Kestoras, Dimitra; Andrews, Melissa R; Dassie, Elisa; Crowther, R Anthony; Stokin, Gorazd B; Tinsley, Jon; Horne, Graeme; Goedert, Michel; Tolkovsky, Aviva M; Spillantini, Maria Grazia.

J Neurosci ; 33(46): 18175-89, 2013 Nov 13.

Article in English | MEDLINE | ID: mdl-24227726

8.

Tau and neurodegeneration.

Goedert, Michel; Crowther, R Anthony; Scheres, Sjors H W; Spillantini, Maria Grazia.

Cytoskeleton (Hoboken) ; 81(1): 95-102, 2024 01.

Article in English | MEDLINE | ID: mdl-38073060

9.

Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.

Schweighauser, Manuel; Murzin, Alexey G; Macdonald, Jennifer; Lavenir, Isabelle; Crowther, R Anthony; Scheres, Sjors H W; Goedert, Michel.

Acta Neuropathol Commun ; 11(1): 160, 2023 10 05.

Article in English | MEDLINE | ID: mdl-37798679

10.

Phenotypic variation of autosomal-dominant corticobasal degeneration.

Jung, Hans H; Bremer, Juliane; Streffer, Johannes; Virdee, Kanwar; Spillantini, Maria Grazia; Crowther, R Anthony; Brugger, Peter; Van Broeckhoven, Christine; Aguzzi, Adriano; Tolnay, Markus.

Eur Neurol ; 67(3): 142-50, 2012.

Article in English | MEDLINE | ID: mdl-22261560

11.

Human beta-synuclein rendered fibrillogenic by designed mutations.

Zibaee, Shahin; Fraser, Graham; Jakes, Ross; Owen, David; Serpell, Louise C; Crowther, R Anthony; Goedert, Michel.

J Biol Chem ; 285(49): 38555-67, 2010 Dec 03.

Article in English | MEDLINE | ID: mdl-20833719

12.

Impact of hepatitis B virus surface protein mutations on the diagnosis of occult hepatitis B virus infection.

El Chaar, Mira; Candotti, Daniel; Crowther, R Anthony; Allain, Jean Pierre.

Hepatology ; 52(5): 1600-10, 2010 Nov.

Article in English | MEDLINE | ID: mdl-20815025

13.

A Brief History of Tau.

Goedert, Michel; Spillantini, Maria Grazia; Crowther, R Anthony.

Clin Chem ; 61(11): 1417-8, 2015 Nov.

Article in English | MEDLINE | ID: mdl-26330509

14.

Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

Ghazi-Tabatabai, Sara; Saksena, Suraj; Short, Judith M; Pobbati, Ajaybabu V; Veprintsev, Dmitry B; Crowther, R Anthony; Emr, Scott D; Egelman, Edward H; Williams, Roger L.

Structure ; 16(9): 1345-56, 2008 Sep 10.

Article in English | MEDLINE | ID: mdl-18786397

15.

The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family.

Spina, Salvatore; Farlow, Martin R; Unverzagt, Frederick W; Kareken, David A; Murrell, Jill R; Fraser, Graham; Epperson, Francine; Crowther, R Anthony; Spillantini, Maria G; Goedert, Michel; Ghetti, Bernardino.

Brain ; 131(Pt 1): 72-89, 2008 Jan.

Article in English | MEDLINE | ID: mdl-18065436

16.

Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.

Zhang, Wenjuan; Falcon, Benjamin; Murzin, Alexey G; Fan, Juan; Crowther, R Anthony; Goedert, Michel; Scheres, Sjors Hw.

Elife ; 82019 02 05.

Article in English | MEDLINE | ID: mdl-30720432

17.

White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration.

Kovacs, Gabor G; Majtenyi, Katalin; Spina, Salvatore; Murrell, Jill R; Gelpi, Ellen; Hoftberger, Romana; Fraser, Graham; Crowther, R Anthony; Goedert, Michel; Budka, Herbert; Ghetti, Bernardino.

J Neuropathol Exp Neurol ; 67(10): 963-75, 2008 Oct.

Article in English | MEDLINE | ID: mdl-18800011

18.

Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity.

L'Hernault, Anne; Greatorex, Jane S; Crowther, R Anthony; Lever, Andrew M L.

Retrovirology ; 4: 90, 2007 Dec 13.

Article in English | MEDLINE | ID: mdl-18078509

19.

Tau protein, the paired helical filament and Alzheimer's disease.

Goedert, Michel; Klug, Aaron; Crowther, R Anthony.

J Alzheimers Dis ; 9(3 Suppl): 195-207, 2006.

Article in English | MEDLINE | ID: mdl-16914859

20.

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

Allen, Bridget; Ingram, Esther; Takao, Masaki; Smith, Michael J; Jakes, Ross; Virdee, Kanwar; Yoshida, Hirotaka; Holzer, Max; Craxton, Molly; Emson, Piers C; Atzori, Cristiana; Migheli, Antonio; Crowther, R Anthony; Ghetti, Bernardino; Spillantini, Maria Grazia; Goedert, Michel.

J Neurosci ; 22(21): 9340-51, 2002 Nov 01.

Article in English | MEDLINE | ID: mdl-12417659

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