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1.

Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.

Jaeger, Kathrin; Bruenle, Steffen; Weinert, Tobias; Guba, Wolfgang; Muehle, Jonas; Miyazaki, Takuya; Weber, Martin; Furrer, Antonia; Haenggi, Noemi; Tetaz, Tim; Huang, Chia-Ying; Mattle, Daniel; Vonach, Jean-Marie; Gast, Alain; Kuglstatter, Andreas; Rudolph, Markus G; Nogly, Przemyslaw; Benz, Joerg; Dawson, Roger J P; Standfuss, Joerg.

Cell ; 178(5): 1222-1230.e10, 2019 08 22.

Article in English | MEDLINE | ID: mdl-31442409

2.

Structural insights into the inhibition of glycine reuptake.

Shahsavar, Azadeh; Stohler, Peter; Bourenkov, Gleb; Zimmermann, Iwan; Siegrist, Martin; Guba, Wolfgang; Pinard, Emmanuel; Sinning, Steffen; Seeger, Markus A; Schneider, Thomas R; Dawson, Roger J P; Nissen, Poul.

Nature ; 591(7851): 677-681, 2021 03.

Article in English | MEDLINE | ID: mdl-33658720

3.

Structure of the µ-opioid receptor-G_i protein complex.

Koehl, Antoine; Hu, Hongli; Maeda, Shoji; Zhang, Yan; Qu, Qianhui; Paggi, Joseph M; Latorraca, Naomi R; Hilger, Daniel; Dawson, Roger; Matile, Hugues; Schertler, Gebhard F X; Granier, Sebastien; Weis, William I; Dror, Ron O; Manglik, Aashish; Skiniotis, Georgios; Kobilka, Brian K.

Nature ; 558(7711): 547-552, 2018 06.

Article in English | MEDLINE | ID: mdl-29899455

4.

Ligand channel in pharmacologically stabilized rhodopsin.

Mattle, Daniel; Kuhn, Bernd; Aebi, Johannes; Bedoucha, Marc; Kekilli, Demet; Grozinger, Nathalie; Alker, Andre; Rudolph, Markus G; Schmid, Georg; Schertler, Gebhard F X; Hennig, Michael; Standfuss, Jörg; Dawson, Roger J P.

Proc Natl Acad Sci U S A ; 115(14): 3640-3645, 2018 04 03.

Article in English | MEDLINE | ID: mdl-29555765

5.

Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.

Bocquet, Nicolas; Kohler, Josiane; Hug, Melanie N; Kusznir, Eric A; Rufer, Arne C; Dawson, Roger J; Hennig, Michael; Ruf, Armin; Huber, Walter; Huber, Sylwia.

Biochim Biophys Acta ; 1848(5): 1224-33, 2015 May.

Article in English | MEDLINE | ID: mdl-25725488

6.

Sav1866 from Staphylococcus aureus and P-glycoprotein: similarities and differences in ATPase activity assessed with detergents as allocrites.

Beck, Andreas; Aänismaa, Päivi; Li-Blatter, Xiaochun; Dawson, Roger; Locher, Kaspar; Seelig, Anna.

Biochemistry ; 52(19): 3297-309, 2013 May 14.

Article in English | MEDLINE | ID: mdl-23600489

7.

Structure of a bacterial multidrug ABC transporter.

Dawson, Roger J P; Locher, Kaspar P.

Nature ; 443(7108): 180-5, 2006 Sep 14.

Article in English | MEDLINE | ID: mdl-16943773

8.

Structure and mechanism of ABC transporter proteins.

Hollenstein, Kaspar; Dawson, Roger J P; Locher, Kaspar P.

Curr Opin Struct Biol ; 17(4): 412-8, 2007 Aug.

Article in English | MEDLINE | ID: mdl-17723295

9.

Identifying Conformation-Selective Heavy-Chain-Only Antibodies Against Membrane Proteins by a Thermal-Shift Scintillation Proximity Assay.

Stohler, Peter; Dawson, Roger J P.

Methods Mol Biol ; 2127: 185-190, 2020.

Article in English | MEDLINE | ID: mdl-32112323

10.

Generation of synthetic nanobodies against delicate proteins.

Zimmermann, Iwan; Egloff, Pascal; Hutter, Cedric A J; Kuhn, Benedikt T; Bräuer, Philipp; Newstead, Simon; Dawson, Roger J P; Geertsma, Eric R; Seeger, Markus A.

Nat Protoc ; 15(5): 1707-1741, 2020 05.

Article in English | MEDLINE | ID: mdl-32269381

11.

Biotinylation of Membrane Proteins for Binder Selections.

Kuhn, Benedikt T; Zimmermann, Iwan; Egloff, Pascal; Hürlimann, Lea M; Hutter, Cedric A J; Miscenic, Christian; Dawson, Roger J P; Seeger, Markus A; Geertsma, Eric R.

Methods Mol Biol ; 2127: 151-165, 2020.

Article in English | MEDLINE | ID: mdl-32112321

12.

Cryo-EM structure of the rhodopsin-Gαi-ßÎ³ complex reveals binding of the rhodopsin C-terminal tail to the gß subunit.

Tsai, Ching-Ju; Marino, Jacopo; Adaixo, Ricardo; Pamula, Filip; Muehle, Jonas; Maeda, Shoji; Flock, Tilman; Taylor, Nicholas Mi; Mohammed, Inayatulla; Matile, Hugues; Dawson, Roger Jp; Deupi, Xavier; Stahlberg, Henning; Schertler, Gebhard.

Elife ; 82019 06 28.

Article in English | MEDLINE | ID: mdl-31251171

13.

Development of an antibody fragment that stabilizes GPCR/G-protein complexes.

Maeda, Shoji; Koehl, Antoine; Matile, Hugues; Hu, Hongli; Hilger, Daniel; Schertler, Gebhard F X; Manglik, Aashish; Skiniotis, Georgios; Dawson, Roger J P; Kobilka, Brian K.

Nat Commun ; 9(1): 3712, 2018 09 13.

Article in English | MEDLINE | ID: mdl-30213947

14.

Synthetic single domain antibodies for the conformational trapping of membrane proteins.

Zimmermann, Iwan; Egloff, Pascal; Hutter, Cedric Aj; Arnold, Fabian M; Stohler, Peter; Bocquet, Nicolas; Hug, Melanie N; Huber, Sylwia; Siegrist, Martin; Hetemann, Lisa; Gera, Jennifer; Gmür, Samira; Spies, Peter; Gygax, Daniel; Geertsma, Eric R; Dawson, Roger Jp; Seeger, Markus A.

Elife ; 72018 05 24.

Article in English | MEDLINE | ID: mdl-29792401

15.

Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP.

Dawson, Roger J P; Locher, Kaspar P.

FEBS Lett ; 581(5): 935-8, 2007 Mar 06.

Article in English | MEDLINE | ID: mdl-17303126

16.

The N-terminal domain of p53 is natively unfolded.

Dawson, Roger; Müller, Lin; Dehner, Alexander; Klein, Christian; Kessler, Horst; Buchner, Johannes.

J Mol Biol ; 332(5): 1131-41, 2003 Oct 03.

Article in English | MEDLINE | ID: mdl-14499615

17.

Mammalian expression, purification, and crystallization of rhodopsin variants.

Mattle, Daniel; Singhal, Ankita; Schmid, Georg; Dawson, Roger; Standfuss, Jörg.

Methods Mol Biol ; 1271: 39-54, 2015.

Article in English | MEDLINE | ID: mdl-25697515

18.

Probing Gαi1 protein activation at single-amino acid resolution.

Sun, Dawei; Flock, Tilman; Deupi, Xavier; Maeda, Shoji; Matkovic, Milos; Mendieta, Sandro; Mayer, Daniel; Dawson, Roger; Schertler, Gebhard F X; Madan Babu, M; Veprintsev, Dmitry B.

Nat Struct Mol Biol ; 22(9): 686-694, 2015 Sep.

Article in English | MEDLINE | ID: mdl-26258638

19.

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein.

Maeda, Shoji; Sun, Dawei; Singhal, Ankita; Foggetta, Marcello; Schmid, Georg; Standfuss, Joerg; Hennig, Michael; Dawson, Roger J P; Veprintsev, Dmitry B; Schertler, Gebhard F X.

PLoS One ; 9(6): e98714, 2014.

Article in English | MEDLINE | ID: mdl-24979345

20.

Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.

Dawson, Roger J P; Benz, Jörg; Stohler, Peter; Tetaz, Tim; Joseph, Catherine; Huber, Sylwia; Schmid, Georg; Hügin, Daniela; Pflimlin, Pascal; Trube, Gerd; Rudolph, Markus G; Hennig, Michael; Ruf, Armin.

Nat Commun ; 3: 936, 2012 Jul 03.

Article in English | MEDLINE | ID: mdl-22760635

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