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1.
Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A Framework for Baseline Levels and Future Implications in Aging and Disease.
Mol Pharmacol
; 105(3): 131-143, 2024 Feb 15.
Article
in English
| MEDLINE | ID: mdl-38164625
2.
Lung cancer-kidney cross talk induces kidney injury, interstitial fibrosis, and enhances cisplatin-induced nephrotoxicity.
Am J Physiol Renal Physiol
; 324(3): F287-F300, 2023 03 01.
Article
in English
| MEDLINE | ID: mdl-36727944
3.
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress.
Arch Toxicol
; 97(6): 1773-1781, 2023 06.
Article
in English
| MEDLINE | ID: mdl-37142755
4.
The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure.
Arch Toxicol
; 97(10): 2697-2705, 2023 10.
Article
in English
| MEDLINE | ID: mdl-37592049
5.
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances.
Arch Toxicol
; 97(1): 189-199, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36138126
6.
Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury.
J Lipid Res
; 63(3): 100179, 2022 03.
Article
in English
| MEDLINE | ID: mdl-35151662
7.
Pharmacological inhibitors of autophagy have opposite effects in acute and chronic cisplatin-induced kidney injury.
Am J Physiol Renal Physiol
; 323(3): F288-F298, 2022 09 01.
Article
in English
| MEDLINE | ID: mdl-35796459
8.
Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis.
Mol Carcinog
; 61(5): 481-493, 2022 05.
Article
in English
| MEDLINE | ID: mdl-35133049
9.
Neutral Ceramidase Mediates Nonalcoholic Steatohepatitis by Regulating Monounsaturated Fatty Acids and Gut IgA+ B Cells.
Hepatology
; 73(3): 901-919, 2021 03.
Article
in English
| MEDLINE | ID: mdl-33185911
10.
Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells.
Toxicol Appl Pharmacol
; 442: 115993, 2022 05 01.
Article
in English
| MEDLINE | ID: mdl-35353990
11.
Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and ß-naphthylamine in immortalized human lung epithelial cells.
Toxicol Appl Pharmacol
; 449: 116095, 2022 08 15.
Article
in English
| MEDLINE | ID: mdl-35662664
12.
Differences in ß-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes.
Arch Toxicol
; 96(11): 2999-3012, 2022 11.
Article
in English
| MEDLINE | ID: mdl-36040704
13.
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen ß-naphthylamine in cryopreserved human hepatocytes.
Arch Toxicol
; 96(12): 3257-3263, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36112171
14.
Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1.
Arch Toxicol
; 96(2): 511-524, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34783865
15.
Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes.
Arch Toxicol
; 95(1): 311-319, 2021 01.
Article
in English
| MEDLINE | ID: mdl-33136180
16.
C57BL/6 mice require a higher dose of cisplatin to induce renal fibrosis and CCL2 correlates with cisplatin-induced kidney injury.
Am J Physiol Renal Physiol
; 319(4): F674-F685, 2020 10 01.
Article
in English
| MEDLINE | ID: mdl-32830540
17.
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes.
Pharmacogenet Genomics
; 30(3): 61-65, 2020 04.
Article
in English
| MEDLINE | ID: mdl-31895247
18.
Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury.
Am J Pathol
; 189(6): 1190-1200, 2019 06.
Article
in English
| MEDLINE | ID: mdl-30926337
19.
UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.
BMC Cancer
; 20(1): 824, 2020 Aug 31.
Article
in English
| MEDLINE | ID: mdl-32867711
20.
Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4'-methylenedianiline.
Arch Toxicol
; 93(8): 2237-2246, 2019 08.
Article
in English
| MEDLINE | ID: mdl-31292670