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BACKGROUND: Although incidence and mortality of lung cancer have been decreasing, health disparities persist among historically marginalized Black, Hispanic, and Asian populations. A targeted literature review was performed to collate the evidence of health disparities among these historically marginalized patients with lung cancer in the U.S. METHODS: Articles eligible for review included 1) indexed in PubMed®, 2) English language, 3) U.S. patients only, 4) real-world evidence studies, and 5) publications between January 1, 2018, and November 8, 2021. RESULTS: Of 94 articles meeting selection criteria, 49 publications were selected, encompassing patient data predominantly between 2004 and 2016. Black patients were shown to develop lung cancer at an earlier age and were more likely to present with advanced-stage disease compared to White patients. Black patients were less likely to be eligible for/receive lung cancer screening, genetic testing for mutations, high-cost and systemic treatments, and surgical intervention compared to White patients. Disparities were also detected in survival, where Hispanic and Asian patients had lower mortality risks compared to White patients. Literature on survival outcomes between Black and White patients was inconclusive. Disparities related to sex, rurality, social support, socioeconomic status, education level, and insurance type were observed. CONCLUSIONS: Health disparities within the lung cancer population begin with initial screening and continue through survival outcomes, with reports persisting well into the latter portion of the past decade. These findings should serve as a call to action, raising awareness of persistent and ongoing inequities, particularly for marginalized populations.
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OBJECTIVE: This report presents estimates for U.S. nursing homes, their current residents, and staff, based on results from the 2004 National Nursing Home Survey (NNHS). Facility data are summarized by facility characteristics and include new data items on special care units and programs, formal contracts with agencies and providers, end-of-life care programs, and electronic information systems. Current residents are presented by characteristics such as demographics, health and functional status, and services received, with new data items on advance directives, falls, use of restraints, hospitalizations, pain management, and medications. The discussion highlights key survey findings, including differences in selected national estimates between the 2004 NNHS and the 1999 survey. METHODS: The 2004 NNHS consisted of a two-stage design with a probability sample of 1,500 nursing facilities in the first stage and up to 12 current residents from each facility in the second stage. This nationally representative sample survey was conducted by the Centers for Disease Control and Prevention's National Center for Health Statistics from August 2004 through January 2005. RESULTS: In 2004, an estimated 1.5 million current residents received nursing home care in 16,100 facilities, the majority of which were proprietary (61.5%) and were located in the Midwest and in the South. Most full-time equivalent employees of the facilities were nursing staff. Most current residents were aged 65 years and older (88.3%), female (71.2%), and white (85.5%). Nearly one-half (48.2%) of all residents were admitted from a hospital or health care facility other than a nursing home or assisted-living-type facility, and 65.3% of all residents had some kind of advance directive.
Subject(s)
Health Care Surveys , Homes for the Aged/statistics & numerical data , Nursing Homes/statistics & numerical data , Aged , Aged, 80 and over , Centers for Disease Control and Prevention, U.S. , Female , Humans , Male , Middle Aged , United States/epidemiologyABSTRACT
OBJECTIVES: To document the extent and appropriateness of use of antipsychotics and benzodiazepines among nursing home residents using a nationally representative survey. METHODS: Cross-sectional analysis of the 2004 National Nursing Home Survey. Bivariate and multivariate analyses examined relationships between resident and facility characteristics and antipsychotic and benzodiazepine use by appropriateness classification among residents aged 60 years and older (N = 12,090). Resident diagnoses and information about behavioral problems were used to categorize antipsychotic and benzodiazepine use as appropriate, potentially appropriate, or having no appropriate indication. RESULTS: More than one quarter (26%) of nursing home residents used an antipsychotic medication, 40% of whom had no appropriate indication for such use. Among the 13% of residents who took benzodiazepines, 42% had no appropriate indication. In adjusted analyses, the odds of residents taking an antipsychotic without an appropriate indication were highest for residents with diagnoses of depression (odds ratio [OR] = 1.31; 95% confidence interval [CI]: 1.12-1.53), dementia (OR = 1.82; 95% CI: 1.52-2.18), and with behavioral symptoms (OR = 1.97, 95% CI: 1.56-2.50). The odds of potentially inappropriate antipsychotic use increased as the percentage of Medicaid residents in a facility increased (OR = 1.08, 95% CI: 1.02-1.15) and decreased as the percentage of Medicare residents increased (OR = 0.46, 95% CI: 0.25-0.83). The odds of taking a benzodiazepine without an appropriate indication were highest among residents who were female (OR = 1.44; 95% CI: 1.18-1.75), white (OR = 1.95; 95% CI: 1.47-2.60), and had behavioral symptoms (OR = 1.69; 95% CI: 1.41-2.01). CONCLUSION: Antipsychotics and benzodiazepines seem to be commonly prescribed to residents lacking an appropriate indication for their use.
Subject(s)
Antipsychotic Agents/therapeutic use , Benzodiazepines/therapeutic use , Drug Utilization/statistics & numerical data , Health Care Surveys/methods , Mental Disorders/drug therapy , Nursing Homes/statistics & numerical data , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , United StatesABSTRACT
OBJECTIVES: To examine laxative use by individuals in hospice who were taking opioids during the last week of life. DESIGN: Retrospective cross-sectional. SETTING: 2007 National Home and Hospice Care Survey. PARTICIPANTS: Individuals in hospice aged 65 and older who were taking opioids during the last week of life (N = 2,825). MEASUREMENTS: Hospice staff were asked the names of all medications and drugs that participants were taking 7 days before and on the day of death while in hospice, including any standing, routine, or as-needed medications." Medications "used" included medications taken and as-needed medications provided in case a symptom developed. Opioids included all opioid-combination drugs. Laxatives included fibers, lubricants, stimulants, and suppositories. RESULTS: Forty-one percent of participants had cancer as the primary hospice diagnosis, 13% heart disease, 12% debility, 11% dementia, 8% lung disease, and 15% other. Overall, 52% of opioid users used a laxative in the last week of life; the proportions of opioid and laxative users did not differ according to diagnosis. Racial minorities taking opioids had lower odds than white participants (odds ratio (OR) = 0.57, 95% confidence interval (CI) = 0.33-0.99) of using laxatives. Participants taking opioids enrolled in hospice for 7 days or less had lower odds of using laxatives than those enrolled for more than 7 days (OR = 0.65, 95% CI = 0.37-0.95), as did those in hospice inpatient, hospital, or other settings (OR = 0.45, 95% CI = 0.43-0.93) than those in long-term care settings. Participants using five or fewer medications had lower odds of using laxatives than those using six to 10 (OR = 6.01, 95% CI = 3.88-9.32) or 11 to 25 medications (OR = 13.80, 95% CI = 8.74-21.80). CONCLUSION: In 2007, slightly more than half of older adults in hospice who were taking opioids used laxatives during the last week of life. Recent quality indicators from the Centers for Medicare and Medicaid Services recommend laxative treatment when opioid therapy is initiated to prevent opioid-induced constipation and are intended to improve laxative use in individuals in hospice treated with opioids.
Subject(s)
Analgesics, Opioid/therapeutic use , Hospice Care , Laxatives/therapeutic use , Medication Therapy Management , Aged , Cross-Sectional Studies , Drug Interactions , Drug-Related Side Effects and Adverse Reactions/prevention & control , Female , Guideline Adherence , Hospice Care/methods , Hospice Care/standards , Humans , Male , Medicaid , Medicare , Medication Therapy Management/standards , Medication Therapy Management/statistics & numerical data , Practice Guidelines as Topic , Quality Improvement , Retrospective Studies , United StatesABSTRACT
OBJECTIVES: To describe medications that older adults in hospice with cancer, dementia, debility, heart disease, and lung disease take during the last week of life. DESIGN: Retrospective cross-sectional study. SETTING: Nationally representative sample of 695 U.S. hospices in the 2007 National Home and Hospice Care Survey. PARTICIPANTS: Individuals aged 65 and older with a primary diagnosis of cancer (49%), dementia (12%), debility (14%), heart disease (16%), or lung disease (10%) who received end-of-life care during their last week of life (N = 2,623). MEASUREMENTS: Medication data were obtained from hospice staff, who were asked, "What are the names of all the medications and drugs the patient was taking 7 days prior to and on the day of his or her death while in hospice? Please include any standing, routine, or PRN medications." RESULTS: The unweighted survey response rate was 71%. The average number of medications taken was 10.2. The most common therapeutic classes were analgesics (98%); antiemetic and antivertigo medications (78%); anxiolytics, sedatives, and hypnotics (76%); anticonvulsants (71%); and laxatives (53%). Approximately one-quarter of the individuals took proton pump inhibitors, anticoagulants, and antidepressants, and fewer than 20% took antacids and antibiotics. A smaller percentage of individuals with dementia and debility than of those with cancer took opioid analgesics. Individuals with heart disease were more likely than individuals in the other clinical cohorts to take diuretics, and those with lung disease were more likely than those in the other clinical cohorts to take bronchodilators. A higher percentage of individuals with dementia and with debility than with cancer and lung disease took antidepressants. CONCLUSION: People continue to receive disease-focused therapies at the end of life rather than therapies exclusively for palliation of symptoms, suggesting that treatments may vary according to the person's primary diagnosis.
Subject(s)
Drug Therapy/statistics & numerical data , Hospice Care , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Humans , Male , Medicare/statistics & numerical data , Retrospective Studies , Terminal Care , United StatesABSTRACT
KEY FINDINGS: Data from the National Study of Long-Term Care Providers. In 2012, more than one-third of participants in adult day services centers were younger than 65. A higher percentage of participants in nonprofit centers than in for-profit centers were younger than 65. About one-half of participants in adult day services centers were non-Hispanic white persons. A higher percentage of participants in for-profit centers than in nonprofit centers were Hispanic or were non-Hispanic and of a race other than black or white. Almost one-third of adult day services center participants had Alzheimer's disease or other dementias, and about one-quarter had a developmental disability. A lower percentage of participants in for-profit than in nonprofit centers had Alzheimer's disease or other dementias or a developmental disability. The 4,800 adult day services centers nationwide provide a variety of services to their 273,200 participants, the majority of whom are older adults and women (1). The number of for-profit adult day services centers has grown in recent years (2). The 1,900 for-profit centers, representing 40% of centers nationally, served nearly one-half (47%) of center participants in 2012 (3). Using data from the National Study of Long-Term Care Providers, this report presents selected characteristics of adult day services center participants in 2012 and compares the characteristics of participants in for-profit centers with those in nonprofit centers.
Subject(s)
Day Care, Medical/statistics & numerical data , Health Facilities, Proprietary/statistics & numerical data , Long-Term Care/statistics & numerical data , Mental Disorders/classification , Organizations, Nonprofit/statistics & numerical data , Activities of Daily Living , Age Distribution , Aged , Aged, 80 and over , Day Care, Medical/economics , Day Care, Medical/organization & administration , Dementia/economics , Dementia/ethnology , Dementia/rehabilitation , Depressive Disorder/economics , Depressive Disorder/ethnology , Developmental Disabilities/economics , Developmental Disabilities/ethnology , Developmental Disabilities/rehabilitation , Ethnicity/statistics & numerical data , Female , Health Care Surveys , Health Facilities, Proprietary/economics , Health Facilities, Proprietary/organization & administration , Humans , Long-Term Care/economics , Long-Term Care/organization & administration , Male , Medicaid/economics , Medicaid/statistics & numerical data , Mental Disorders/economics , Mental Disorders/ethnology , Mental Disorders/rehabilitation , Middle Aged , Organizations, Nonprofit/economics , Organizations, Nonprofit/organization & administration , Ownership , Sex Distribution , United States/epidemiologyABSTRACT
KEY FINDINGS: Data from the National Study of Long-Term Care Providers. In 2012, 40% of the 4,800 adult day services centers were for-profit entities, serving nearly one-half of the 272,300 center participants. About 60% of adult day services centers used a standardized tool to screen for cognitive impairment, and about 20% used a standardized tool for depression screening. A greater percentage of for-profit than nonprofit centers used these tools. More than one-half of adult day services centers provided skilled nursing, therapeutic, and social work services, while less than one-half of centers provided mental health, pharmacy, and dental services. With the exception of social work services, a greater percentage of for-profit than nonprofit centers provided these services. Almost all adult day services centers provided daily transportation to and from the center. The most recent data estimate that 4,800 adult day services centers nationwide serve nearly a quarter million participants daily (1). Unlike other long-term care providers, such as nursing homes, home health agencies, hospices, and residential care communities, the majority of adult day services centers are nonprofit (1). However, for-profit ownership of adult day services centers appears to be increasing, from 27% in 2010 to 40% in 2012 (2). Using data from the National Study of Long-Term Care Providers, this report presents national estimates for characteristics of adult day services centers in 2012 and compares them by type of center ownership.
Subject(s)
Day Care, Medical/organization & administration , Day Care, Medical/statistics & numerical data , Adult , Aged , Cognition Disorders/diagnosis , Depression/diagnosis , Health Services Research , Humans , Mass Screening/statistics & numerical data , Mental Health Services/statistics & numerical data , Middle Aged , Nursing Care/statistics & numerical data , Organizations, Nonprofit/organization & administration , Organizations, Nonprofit/statistics & numerical data , Ownership , Pharmaceutical Services/statistics & numerical data , Social Work/statistics & numerical data , United StatesABSTRACT
OBJECTIVES: To estimate infection prevalence and explore associated risk factors in nursing home (NH) residents, individuals receiving home health care (HHC), and individuals receiving hospice care. DESIGN: Cross-sectional. SETTING: Nationally representative samples of 1,174 U.S. NHs in the 2004 National Nursing Home Survey (NNHS) and 1,036 U.S. HHC and hospice agencies in the 2007 National Home and Hospice Care Survey (NHHCS). PARTICIPANTS: A nationally representative sample of 12,270 NH residents, 4,394 individuals receiving HHC, and 4,410 individuals receiving hospice care. MEASUREMENTS: International Classification of Diseases, Ninth Revision, Clinical Modification, codes were used to identify the presence of infection, including community-acquired infection and those acquired during earlier healthcare exposures. RESULTS: Unweighted response rates were 78% for the 2004 NHHS and 67% for the 2007 NHHCS. Approximately 12% of NH residents and 12% of individuals receiving HHC had an infection at the time of the survey interview, and more than 10% of individuals receiving hospice care had an infection when discharged from hospice care. The most common infections were urinary tract infection (3.05.2%), pneumonia (2.24.4%), and cellulitis (1.62.0%). Short length of care and recent inpatient stay in a healthcare facility were associated with infections in all three populations. Taking 10 or more medications and urinary catheter exposure were significant in two of these three long-term care populations. CONCLUSION: Infection prevalence in HHC, hospice, and NH populations is similar. Although these infections may be community acquired or acquired during earlier healthcare exposures, these findings fill an important gap in understanding the national infection burden and may help inform future research on infection epidemiology and prevention strategies in long-term care populations.
Subject(s)
Home Care Services , Hospice Care , Infections/epidemiology , Nursing Homes , Adult , Aged , Aged, 80 and over , Cellulitis/epidemiology , Cross-Sectional Studies , Female , Home Care Services/statistics & numerical data , Hospice Care/statistics & numerical data , Humans , Long-Term Care , Male , Nursing Homes/statistics & numerical data , Pneumonia/epidemiology , Prevalence , United States/epidemiology , Urinary Tract Infections/epidemiologyABSTRACT
OBJECTIVES: This methods report provides an overview of the redesigned National Home and Hospice Care Survey (NHHCS) conducted in 2007. NHHCS is a national probability sample survey that collects data on U.S. home health and hospice care agencies, their staffs and services, and the people they serve. The redesigned survey included computerized data collection, greater survey content, increased sample sizes for current home health care patients and hospice care discharges, and a first-ever supplemental survey called the National Home Health Aide Survey. METHODS: The 2007 NHHCS was conducted between August 2007 and February 2008. NHHCS used a two-stage probability sampling design in which agencies providing home health and/or hospice care were sampled. Then, up to 10 current patients were sampled from each home health care agency, up to 10 discharges from each hospice care agency, and a combination of up to 10 patients/discharges from each agency that provided both home health and hospice care services. In-person interviews were conducted with agency directors and their designated staff; no interviews were conducted directly with patients. The survey instrument contained agency- and person-level modules, sampling modules, and a self-administered staffing questionnaire. RESULTS: Data were collected on 1036 agencies, 4683 current home health care patients, and 4733 hospice care discharges. The first-stage agency weighted response rate (for differential probabilities of selection) was 59%. The second-stage patient/discharge weighted response rate was 96%. Three public-use files were released: an agency-level file, a patient/discharge-level file, and a medication file. The files include sampling weights, which are necessary to generate national estimates, and design variables to enable users to calculate accurate standard errors.
Subject(s)
Health Care Surveys/instrumentation , Home Care Agencies/statistics & numerical data , Hospice Care/statistics & numerical data , Research Design , United StatesABSTRACT
BACKGROUND: Despite the need for and benefits of medications, polypharmacy (defined here as concurrent use of > or =9 medications) in nursing home residents is a concern. As the number of medications taken increases, so does the risk for adverse events. Monitoring polypharmacy in this population is important and can improve the quality of nursing home care. OBJECTIVES: The aims of this article were to estimate the use of polypharmacy in residents of nursing homes in the United States, to examine the associations between select resident and facility characteristics and polypharmacy, and to determine the leading therapeutic subclasses included in the polypharmacy received by these nursing home residents. METHODS: This was a retrospective, cross-sectional study of a nationally representative sample of US nursing home residents in 2004; the outcome was use of polypharmacy. The 2004 National Nursing Home Survey was used to collect medication data and other resident and facility information. Resident characteristics included age, sex, race, primary payment source, number of comorbidities, number of activities of daily living (ADLs) for which the resident required assistance, and length of stay (LOS) since admission. Facility characteristics included ownership and size (number of beds). RESULTS: Of 13,507 nursing home residents who received care, 13,403 had valid responses for all 9 independent variables in the analyses. The prevalence of polypharmacy among nursing home residents in 2004 was approximately 40%. A multiple regression model controlling for resident and facility factors revealed that the odds of receiving polypharmacy were higher for residents who were female (odds ratio [OR] = 1.10; 95% CI, 1.00-1.20), were white, had Medicaid as a primary payer, had >3 comorbidities (OR = 1.57-5.18; 95% CI, 1.36-6.15), needed assistance with < or =4 ADLs, had an LOS since admission of 3 to <6 months (OR = 1.25; 95% CI, 1.04-1.50), and received care in a small, not- for-profit facility (data not shown for reference levels [OR = 1.00]). The most frequently reported medications for residents who received polypharmacy included gastrointestinal agents (laxatives, 47.5%; agents for acid/peptic disorders, 43.3%), drugs that affect the central nervous system (antidepressants, 46.3%; antipsychotics or antimanics, 25.9%), and pain relievers (nonnarcotic analgesics, 43.6%; antipyretics, 41.2%; antiarthritics, 31.2%). CONCLUSIONS: Despite awareness of polypharmacy and its potential consequences in older patients, results of our analysis suggest that polypharmacy remains widespread in US nursing homes. Although complex medication regimens are often necessary for nursing home residents, monitoring polypharmacy and its consequences may improve the quality of nursing home care and reduce unnecessary health care spending related to adverse events.
Subject(s)
Health Care Surveys , Homes for the Aged/standards , Homes for the Aged/trends , Nursing Homes/standards , Nursing Homes/trends , Polypharmacy , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Health Care Surveys/methods , Health Care Surveys/trends , Homes for the Aged/statistics & numerical data , Humans , Male , Middle Aged , Nursing Homes/statistics & numerical data , Retrospective Studies , United States/epidemiologyABSTRACT
Objectives-This methods report provides an overview of how medication data were collected and processed in the 2004 National Nursing Home Survey (NNHS) and how analysts may use the medication data. The 2004 survey marked the first time that medication data were collected on sampled nursing home residents in the NNHS. Information about medications, which are an important component of nursing home care, can help policy makers, researchers, and members of the long-term care community better understand which medications are taken by U.S. nursing home residents. Methods-The medication data were collected in the Prescribed Medications (PM) module of the 2004 NNHS. The computer-assisted personal interviewing (CAPI) instrument, which included a drug lookup list, allowed interviewers to enter a maximum of 25 medications taken on the day before the facility interview and a maximum of 25 medications taken regularly but not on the day before the facility interview. This medication information, which is documented in residents' medication administration records, was collected during a face-to-face interview at the nursing home facilities. All data were provided by facility respondents who used residents' administrative and medical records to answer the survey items. The data were entered into the CAPI instrument that was loaded onto each interviewer's computer laptop. Results and conclusions-Data were collected on 13,507 current residents, 98.5 percent of whom took one or more medications. A stand-alone PM Public-use File has been released. This file, which includes the sampling weight and design variables from the resident file, can be linked to the 2004 NNHS Current Resident Public-use File to generate national estimates on medications by various resident characteristics.