Search details
1.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Nature
; 613(7945): 767-774, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36450356
2.
Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.
Proc Natl Acad Sci U S A
; 118(16)2021 04 20.
Article
in English
| MEDLINE | ID: mdl-33846240
3.
Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide.
Molecules
; 28(22)2023 Nov 11.
Article
in English
| MEDLINE | ID: mdl-38005269
4.
Solid-Phase Synthesis of the Bicyclic Peptide OL-CTOP Containing Two Disulfide Bridges, and an Assessment of Its In Vivo µ-Opioid Receptor Antagonism after Nasal Administration.
Molecules
; 28(4)2023 Feb 15.
Article
in English
| MEDLINE | ID: mdl-36838810
5.
Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use.
Int J Mol Sci
; 23(2)2022 Jan 06.
Article
in English
| MEDLINE | ID: mdl-35054797
6.
Bis-Cyclic Guanidine Heterocyclic Peptidomimetics as Opioid Ligands with Mixed µ-, κ- and δ-Opioid Receptor Interactions: A Potential Approach to Novel Analgesics.
Int J Mol Sci
; 23(17)2022 Aug 25.
Article
in English
| MEDLINE | ID: mdl-36077029
7.
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain.
Molecules
; 27(11)2022 Jun 04.
Article
in English
| MEDLINE | ID: mdl-35684553
8.
Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal.
Cell Mol Neurobiol
; 41(5): 1131-1143, 2021 Jul.
Article
in English
| MEDLINE | ID: mdl-33433723
9.
Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles.
Molecules
; 25(17)2020 Sep 02.
Article
in English
| MEDLINE | ID: mdl-32887303
10.
Antinociceptive activity of thiazole-containing cyclized DAMGO and Leu-(Met) enkephalin analogs.
Org Biomol Chem
; 17(21): 5305-5315, 2019 06 07.
Article
in English
| MEDLINE | ID: mdl-31094391
11.
A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluation.
Org Biomol Chem
; 15(37): 7796-7801, 2017 Sep 26.
Article
in English
| MEDLINE | ID: mdl-28875208
12.
Stress-induced increases in depression-like and cocaine place-conditioned behaviors are reversed by disruption of memories during reconsolidation.
Behav Pharmacol
; 25(5-6): 599-608, 2014 Sep.
Article
in English
| MEDLINE | ID: mdl-25083575
13.
SRI-30827, a novel allosteric modulator of the dopamine transporter, alleviates HIV-1 Tat-induced potentiation of cocaine conditioned place preference in mice.
NeuroImmune Pharm Ther
; 3(1): 1-6, 2024 Mar 25.
Article
in English
| MEDLINE | ID: mdl-38711842
14.
Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception.
FASEB J
; 26(2): 947-54, 2012 Feb.
Article
in English
| MEDLINE | ID: mdl-22038051
15.
The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior.
J Nat Prod
; 76(3): 433-8, 2013 Mar 22.
Article
in English
| MEDLINE | ID: mdl-23327691
16.
Tryptophan Substitution in CJ-15,208 (cyclo[Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of Extinguished Cocaine-Conditioned Place Preference.
Pharmaceuticals (Basel)
; 16(9)2023 Aug 29.
Article
in English
| MEDLINE | ID: mdl-37765026
17.
An analog of [d-Trp]CJ-15,208 exhibits kappa opioid receptor antagonism following oral administration and prevents stress-induced reinstatement of extinguished morphine conditioned place preference.
Pharmacol Biochem Behav
; 217: 173405, 2022 06.
Article
in English
| MEDLINE | ID: mdl-35584724
18.
Expression of Human Immunodeficiency Virus Transactivator of Transcription (HIV-Tat1-86) Protein Alters Nociceptive Processing that is Sensitive to Anti-Oxidant and Anti-Inflammatory Interventions.
J Neuroimmune Pharmacol
; 17(1-2): 152-164, 2022 06.
Article
in English
| MEDLINE | ID: mdl-33619645
19.
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
Neuropharmacology
; 220: 109239, 2022 Dec 01.
Article
in English
| MEDLINE | ID: mdl-36126727
20.
Binge ethanol consumption-associated behavioral impairments in male mice using a gelatin-based drinking-in-the dark model.
Alcohol
; 95: 25-36, 2021 09.
Article
in English
| MEDLINE | ID: mdl-34029701