Search details
1.
Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Proc Natl Acad Sci U S A
; 110(4): 1273-8, 2013 Jan 22.
Article
in English
| MEDLINE | ID: mdl-23288897
2.
Recent developments in cyclin-dependent kinase biochemical and structural studies.
Biochim Biophys Acta
; 1804(3): 511-9, 2010 Mar.
Article
in English
| MEDLINE | ID: mdl-19822225
3.
Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design.
Structure
; 16(2): 228-38, 2008 Feb.
Article
in English
| MEDLINE | ID: mdl-18275814
4.
Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase.
ACS Med Chem Lett
; 11(4): 497-505, 2020 Apr 09.
Article
in English
| MEDLINE | ID: mdl-32292556
5.
Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases.
Cancer Res
; 67(17): 8325-34, 2007 Sep 01.
Article
in English
| MEDLINE | ID: mdl-17804748
6.
N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine.
Mol Cancer Ther
; 7(9): 2713-24, 2008 Sep.
Article
in English
| MEDLINE | ID: mdl-18790752
7.
Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.
J Med Chem
; 51(4): 737-51, 2008 Feb 28.
Article
in English
| MEDLINE | ID: mdl-18232649
8.
Activation and catalysis of the di-heme cytochrome c peroxidase from Paracoccus pantotrophus.
Structure
; 14(1): 107-17, 2006 Jan.
Article
in English
| MEDLINE | ID: mdl-16407070
9.
The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery.
Essays Biochem
; 61(5): 495-503, 2017 11 08.
Article
in English
| MEDLINE | ID: mdl-29118096
10.
Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines.
Eur J Med Chem
; 126: 1118-1128, 2017 Jan 27.
Article
in English
| MEDLINE | ID: mdl-28039837
11.
Structure and mechanism in the bacterial dihaem cytochrome c peroxidases.
J Inorg Biochem
; 100(4): 551-67, 2006 Apr.
Article
in English
| MEDLINE | ID: mdl-16434100
12.
Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins.
Curr Protein Pept Sci
; 15(5): 504-17, 2014.
Article
in English
| MEDLINE | ID: mdl-24555901
13.
An inhibitor's-eye view of the ATP-binding site of CDKs in different regulatory states.
ACS Chem Biol
; 9(6): 1251-6, 2014 Jun 20.
Article
in English
| MEDLINE | ID: mdl-24669831
14.
Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer.
PLoS One
; 9(8): e105688, 2014.
Article
in English
| MEDLINE | ID: mdl-25144743
15.
8-Substituted O(6)-cyclohexylmethylguanine CDK2 inhibitors: using structure-based inhibitor design to optimize an alternative binding mode.
J Med Chem
; 57(1): 56-70, 2014 Jan 09.
Article
in English
| MEDLINE | ID: mdl-24304238
16.
ZOMES: the intriguing interplay of PCI complexes and the ubiquitin in protein homeostasis.
Cell Death Dis
; 8(8): e3021, 2017 08 24.
Article
in English
| MEDLINE | ID: mdl-28837155
17.
An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem Biol
; 19(8): 1028-40, 2012 Aug 24.
Article
in English
| MEDLINE | ID: mdl-22921070
18.
Redox-linked structural changes associated with the formation of a catalytically competent form of the diheme cytochrome c peroxidase from Pseudomonas aeruginosa.
Biochemistry
; 47(7): 1947-56, 2008 Feb 19.
Article
in English
| MEDLINE | ID: mdl-18217775
19.
Searching for cyclin-dependent kinase inhibitors using a new variant of the cope elimination.
J Am Chem Soc
; 128(18): 6012-3, 2006 May 10.
Article
in English
| MEDLINE | ID: mdl-16669651
20.
Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism.
Biochemistry
; 44(6): 1755-67, 2005 Feb 15.
Article
in English
| MEDLINE | ID: mdl-15697201