ABSTRACT
Background and Aims: Postoperative sore throat (POST) is a minor but distressing complication following general anesthesia. The current literature on the effect of preoperative nebulization with dexmedetomidine, or ketamine on POST is, however, sparse. So, we compared the effect of preoperative nebulization with these drugs on POST. Material and Methods: One hundred and thirty-two American Society of Anaesthesiology (ASA) grade I-II patients undergoing elective laparoscopic surgeries under general anesthesia were randomized into three equal groups: D, K, or C to receive dexmedetomidine, ketamine, or saline as preoperative nebulization, respectively. The primary objective was to compare the incidence and severity of POST, as inferred from the patient interviews at 2, 6, 12, 24-h postoperatively. Results: Group D had a significantly lower incidence (29.5%) and severity (12: mild; 1: moderate) of POST compared to group K (54.5% [21: mild; 3: moderate]) and group C (56.8% [19: mild; 6: moderate]), at 2-h postoperatively. The same trend was observed at 6-h postoperatively (group D: 22.7% [9: mild; 1: moderate]); group K: (40.9% [17: mild; 1: moderate]); group C (50% [17: mild; 5: moderate]). The mean arterial pressure was significantly lower in group D at 15 min intraoperatively (84.09 mmHg, P = 0.018) and immediate postoperatively (97.60 mmHg, P = 0.034). The postoperative sedation, nausea, and vomiting was not statistically significant. Conclusion: Preoperative nebulization with dexmedetomidine is effective in the reduction of the incidence and severity of early POST.
ABSTRACT
INTRODUCTION: Superficial arteries, such as radial and dorsalis pedis arteries, are commonly cannulated for invasive blood pressure monitoring. Failure to cannulate these arteries necessitates alternate arteries, such as the posterior tibial artery (PTA). The deep-seated anatomy of PTA makes arterial cannulation precarious by the palpatory technique. Ultrasound guidance during PTA cannulation may overcome this problem. With this background, we evaluated the ultrasound-guided (USG) versus palpatory method for PTA cannulation with respect to the first attempt's success and number of attempts. METHODS: A total of 240 American Society of Anesthesiology (ASA) physical status I-IV adult patients undergoing major surgeries requiring arterial cannulation were randomly allocated (1:1) to group A (USG-guided cannulation, n = 120) and Group B (cannulation by palpatory technique, n =120). PTA was cannulated by either of the techniques according to randomization. Data were analyzed and compared in both groups for first-attempt success, number of attempts, assessment time, cannulation time, and complications. RESULT: The successful cannulation in the first attempt in Group A was 25.8% (n = 31), and in Group B, it was 12.5% (n = 15) (p = 0.009). In Group A, 78.3% of patients (n = 94) had successful cannulation, and in group B, 65% of patients (n =78) had successful cannulation (p = 0.022). Both groups had similar assessment time (p = 0.348) and cannulation time (p = 0.864). CONCLUSION: USG-guided PTA cannulation offers a greater chance of success without any added increase in procedure time.