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Results 1 - 20 de 101

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1.

Ubiquitin and membrane protein turnover: from cradle to grave.

MacGurn, Jason A; Hsu, Pi-Chiang; Emr, Scott D.

Annu Rev Biochem ; 81: 231-59, 2012.

Article in English | MEDLINE | ID: mdl-22404628

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2.

The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices.

Henne, William Mike; Buchkovich, Nicholas J; Zhao, Yingying; Emr, Scott D.

Cell ; 151(2): 356-71, 2012 Oct 12.

Article in English | MEDLINE | ID: mdl-23063125

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3.

TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor.

MacGurn, Jason A; Hsu, Pi-Chiang; Smolka, Marcus B; Emr, Scott D.

Cell ; 147(5): 1104-17, 2011 Nov 23.

Article in English | MEDLINE | ID: mdl-22118465

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4.

Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites.

Stefan, Christopher J; Manford, Andrew G; Baird, Daniel; Yamada-Hanff, Jason; Mao, Yuxin; Emr, Scott D.

Cell ; 144(3): 389-401, 2011 Feb 04.

Article in English | MEDLINE | ID: mdl-21295699

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5.

The Hob proteins are novel and conserved lipid-binding proteins at ER-PM contact sites.

Neuman, Sarah D; Jorgensen, Jeff R; Cavanagh, Amy T; Smyth, Jeremy T; Selegue, Jane E; Emr, Scott D; Bashirullah, Arash.

J Cell Sci ; 135(5)2022 03 01.

Article in English | MEDLINE | ID: mdl-34415038

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403981
https://dx.doi.org/10.1242/jcs.259086

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6.

Functional reconstitution of ESCRT-III assembly and disassembly.

Saksena, Suraj; Wahlman, Judit; Teis, David; Johnson, Arthur E; Emr, Scott D.

Cell ; 136(1): 97-109, 2009 Jan 09.

Article in English | MEDLINE | ID: mdl-19135892

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104304
https://dx.doi.org/10.1016/j.cell.2008.11.013

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7.

Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.

Lin, Charles H; MacGurn, Jason A; Chu, Tony; Stefan, Christopher J; Emr, Scott D.

Cell ; 135(4): 714-25, 2008 Nov 14.

Article in English | MEDLINE | ID: mdl-18976803

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8.

Ubiquitin-dependent lysosomal membrane protein sorting and degradation.

Li, Ming; Rong, Yueguang; Chuang, Ya-Shan; Peng, Dan; Emr, Scott D.

Mol Cell ; 57(3): 467-78, 2015 Feb 05.

Article in English | MEDLINE | ID: mdl-25620559

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9.

SnapShot: the ESCRT machinery.

Teis, David; Saksena, Suraj; Emr, Scott D.

Cell ; 137(1): 182-182.e1, 2009 Apr 03.

Article in English | MEDLINE | ID: mdl-19345195

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10.

Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1.

Han, Bong-Kwan; Emr, Scott D.

Genes Dev ; 25(9): 984-95, 2011 May 01.

Article in English | MEDLINE | ID: mdl-21536737

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084031
https://dx.doi.org/10.1101/gad.1998611

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11.

The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P2 synthesis.

Ling, Yading; Stefan, Christopher J; Macgurn, Jason A; Audhya, Anjon; Emr, Scott D.

EMBO J ; 31(13): 2882-94, 2012 Jun 29.

Article in English | MEDLINE | ID: mdl-22562153

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395088
https://dx.doi.org/10.1038/emboj.2012.127

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12.

The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis.

Han, Bong-Kwan; Emr, Scott D.

J Biol Chem ; 288(28): 20633-45, 2013 Jul 12.

Article in English | MEDLINE | ID: mdl-23733183

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711327
https://dx.doi.org/10.1074/jbc.M113.452813

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13.

ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formation.

Teis, David; Saksena, Suraj; Judson, Bret L; Emr, Scott D.

EMBO J ; 29(5): 871-83, 2010 Mar 03.

Article in English | MEDLINE | ID: mdl-20134403

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837172
https://dx.doi.org/10.1038/emboj.2009.408

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14.

Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function.

Manford, Andrew; Xia, Tian; Saxena, Ajay Kumar; Stefan, Christopher; Hu, Fenghua; Emr, Scott D; Mao, Yuxin.

EMBO J ; 29(9): 1489-98, 2010 May 05.

Article in English | MEDLINE | ID: mdl-20389282

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876947
https://dx.doi.org/10.1038/emboj.2010.57

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15.

Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation.

MacDonald, Chris; Buchkovich, Nicholas J; Stringer, Daniel K; Emr, Scott D; Piper, Robert C.

EMBO Rep ; 13(4): 331-8, 2012 Apr.

Article in English | MEDLINE | ID: mdl-22370727

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321151
https://dx.doi.org/10.1038/embor.2012.18

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16.

A role for Vps13-mediated lipid transfer at the ER-endosome contact site in ESCRT-mediated sorting.

Suzuki, Sho W; West, Matthew; Zhang, Yichen; Fan, Jenny S; Roberts, Rachel T; Odorizzi, Greg; Emr, Scott D.

J Cell Biol ; 223(4)2024 04 01.

Article in English | MEDLINE | ID: mdl-38319250

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847051
https://dx.doi.org/10.1083/jcb.202307094

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17.

TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.

Morozova, Nadya; Liang, Yongheng; Tokarev, Andrei A; Chen, Shu H; Cox, Randal; Andrejic, Jelena; Lipatova, Zhanna; Sciorra, Vicki A; Emr, Scott D; Segev, Nava.

Nat Cell Biol ; 8(11): 1263-9, 2006 Nov.

Article in English | MEDLINE | ID: mdl-17041589

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18.

Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4.

Obita, Takayuki; Saksena, Suraj; Ghazi-Tabatabai, Sara; Gill, David J; Perisic, Olga; Emr, Scott D; Williams, Roger L.

Nature ; 449(7163): 735-9, 2007 Oct 11.

Article in English | MEDLINE | ID: mdl-17928861

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19.

Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.

Garrenton, Lindsay S; Stefan, Christopher J; McMurray, Michael A; Emr, Scott D; Thorner, Jeremy.

Proc Natl Acad Sci U S A ; 107(26): 11805-10, 2010 Jun 29.

Article in English | MEDLINE | ID: mdl-20547860

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900652
https://dx.doi.org/10.1073/pnas.1005817107

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20.

The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology.

Efe, Jem A; Botelho, Roberto J; Emr, Scott D.

Curr Opin Cell Biol ; 17(4): 402-8, 2005 Aug.

Article in English | MEDLINE | ID: mdl-15975782

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