ABSTRACT
We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions. The patient presented with mucoid anal adenocarcinoma. He was treated with preoperative neoadjuvant chemotherapy (5-FU and leucovorin) and external radiation therapy plus laparoscopy-assisted abdominoperineal amputation. Mucoid adenocarcinoma on chronic perianal fistula is an infrequent process. Late diagnosis is associated with a poor prognosis.
Subject(s)
Adenocarcinoma, Mucinous/complications , Adenocarcinoma, Mucinous/therapy , Antimetabolites, Antineoplastic/therapeutic use , Anus Neoplasms/complications , Anus Neoplasms/therapy , Fluorouracil/therapeutic use , Laparoscopy , Leucovorin/therapeutic use , Rectal Fistula/complications , Chemotherapy, Adjuvant , Chronic Disease , Combined Modality Therapy , Digestive System Surgical Procedures/methods , Humans , Male , Middle Aged , Perineum/surgery , Radiotherapy, AdjuvantABSTRACT
Paciente varón con una fístula perianal de 30 años de evolución tratado en varias ocasiones. Presentó un adenocarcinoma mucoide anal. Fue tratado con quimioterapia (5-FU y leucovorín) y radioterapia externa de forma preoperatoria y amputación abdominoperineal laparoscópica asistida. El adenocarcinoma mucoide sobre fístula perianal crónica es un proceso infrecuente y de diagnóstico tardío asociado a un mal pronóstico (AU)
We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions. The patient presented with mucoid anal adenocarcinoma. He was treated with preoperative neoadjuvant chemotherapy (5-FU and leucovorin) and external radiation therapy plus laparoscopy-assisted abdominoperineal amputation. Mucoid adenocarcinoma on chronic perianal fistula is an infrequent process. Late diagnosis is associated with a poor prognosis (AU)