ABSTRACT
Mediastinal lesions occur in a wide variety of clinical conditions. Metastatic granulosa cell tumour (GCT) in the mediastinum is a rare occurrence. We report a case of a woman who had a metastatic (GCT) in her mediastinum 40 years after treatment of the initial neoplasm. Surgical resection of the mediastinal mass revealed a low-grade epithelioid neoplasm with coffee bean-shaped nuclei and immunohistochemical stains that were consistent with metastatic GCT.
ABSTRACT
Carcinoma ex pleomorphic adenoma is a rare salivary gland malignancy with a poor prognosis that can metastasize to the lungs. Endobronchial metastasis and associated bronchoscopic characteristics have not been described in the literature. Cryotherapy is a safe and efficacious palliative treatment option for obstructive bronchial tumors that can be performed with flexible bronchoscopy. We report the successful use of cryotherapy for the palliation of an aggressive parotid malignancy with extraordinary endobronchial metastases and describe bronchoscopic characteristics of this unique entity.
Subject(s)
Adenoma, Pleomorphic/therapy , Bronchial Neoplasms/secondary , Bronchial Neoplasms/therapy , Cryotherapy , Parotid Neoplasms/therapy , Adenoma, Pleomorphic/pathology , Aged , Bronchial Neoplasms/pathology , Bronchoscopy , Female , Humans , Palliative Care , Parotid Neoplasms/pathologyABSTRACT
Transbronchial needle aspiration (TBNA) is a safe procedure with a reported complication rate of less than 1%. Pneumomediastinum after TBNA has not been reported in the English literature in the past. We present the case of a 65-year-old woman with widely metastatic small cell carcinoma, who developed pneumomediastinum after flexible bronchoscopy with TBNA. A persistent visible defect in the bronchial wall at the site of the needle insertion strongly implicated the TBNA as the cause of the pneumomediastinum.