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1.
A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress.
Proc Natl Acad Sci U S A
; 121(4): e2317344121, 2024 Jan 23.
Article
in English
| MEDLINE | ID: mdl-38241440
2.
Stable Interstrand Cross-Links Generated from the Repair of 1,N6-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2.
J Am Chem Soc
; 146(15): 10381-10392, 2024 Apr 17.
Article
in English
| MEDLINE | ID: mdl-38573229
3.
5-Chloro-2'-deoxycytidine Induces a Distinctive High-Resolution Mutational Spectrum of Transition Mutations In Vivo.
Chem Res Toxicol
; 37(3): 486-496, 2024 03 18.
Article
in English
| MEDLINE | ID: mdl-38394377
4.
7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces AâT transversions in Escherichia coli.
Nucleic Acids Res
; 50(6): 3056-3069, 2022 04 08.
Article
in English
| MEDLINE | ID: mdl-35234900
5.
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases.
Chem Res Toxicol
; 35(10): 1655-1675, 2022 10 17.
Article
in English
| MEDLINE | ID: mdl-35881568
6.
Metallocalix[4]arene Polymers for Gravimetric Detection of N-Nitrosodialkylamines.
J Am Chem Soc
; 143(47): 19809-19815, 2021 12 01.
Article
in English
| MEDLINE | ID: mdl-34793165
7.
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro.
Nucleic Acids Res
; 47(11): 5522-5529, 2019 06 20.
Article
in English
| MEDLINE | ID: mdl-31114894
8.
Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O6-Methylguanine Methyltransferase, MGMT.
Chem Res Toxicol
; 33(2): 625-633, 2020 02 17.
Article
in English
| MEDLINE | ID: mdl-31841318
9.
Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.
Proc Natl Acad Sci U S A
; 114(15): E3101-E3109, 2017 04 11.
Article
in English
| MEDLINE | ID: mdl-28351974
10.
NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice.
Proc Natl Acad Sci U S A
; 114(16): 4207-4212, 2017 04 18.
Article
in English
| MEDLINE | ID: mdl-28373545
11.
Mutagenicity of Helicobacter hepaticus infection in the lower bowel mucosa of 129/SvEv Rag2-/- Il10-/- gpt delta mice is influenced by sex.
Int J Cancer
; 145(4): 1042-1054, 2019 08 15.
Article
in English
| MEDLINE | ID: mdl-30977112
12.
Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity.
Proc Natl Acad Sci U S A
; 112(11): 3229-34, 2015 Mar 17.
Article
in English
| MEDLINE | ID: mdl-25733867
13.
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Proc Natl Acad Sci U S A
; 112(33): E4571-80, 2015 Aug 18.
Article
in English
| MEDLINE | ID: mdl-26243878
14.
Role of tautomerism in RNA biochemistry.
RNA
; 21(1): 1-13, 2015 Jan.
Article
in English
| MEDLINE | ID: mdl-25516996
15.
1,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication Backgrounds.
Chem Res Toxicol
; 30(5): 1230-1239, 2017 05 15.
Article
in English
| MEDLINE | ID: mdl-28394575
16.
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions.
Chem Res Toxicol
; 30(4): 1102-1110, 2017 04 17.
Article
in English
| MEDLINE | ID: mdl-28269980
17.
Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Nucleic Acids Res
; 43(11): 5489-500, 2015 Jun 23.
Article
in English
| MEDLINE | ID: mdl-25837992
18.
Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine.
Proc Natl Acad Sci U S A
; 111(32): E3252-9, 2014 Aug 12.
Article
in English
| MEDLINE | ID: mdl-25071207
19.
The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.
J Biol Chem
; 290(34): 20734-20742, 2015 Aug 21.
Article
in English
| MEDLINE | ID: mdl-26152727
20.
Adaptive Response Enzyme AlkB Preferentially Repairs 1-Methylguanine and 3-Methylthymine Adducts in Double-Stranded DNA.
Chem Res Toxicol
; 29(4): 687-93, 2016 Apr 18.
Article
in English
| MEDLINE | ID: mdl-26919079