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1.
Antitumor activity of the PI3K δ-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer.
Breast Cancer Res Treat
; 199(1): 13-23, 2023 May.
Article
in English
| MEDLINE | ID: mdl-36913051
2.
Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells.
Breast Cancer Res Treat
; 201(1): 43-56, 2023 Aug.
Article
in English
| MEDLINE | ID: mdl-37318638
3.
Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models.
Haematologica
; 105(11): 2584-2591, 2020 11 01.
Article
in English
| MEDLINE | ID: mdl-33131247
4.
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.
Biochim Biophys Acta
; 1864(11): 1506-17, 2016 11.
Article
in English
| MEDLINE | ID: mdl-27530298
5.
Model-based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2-positive advanced or metastatic breast cancer patients.
CPT Pharmacometrics Syst Pharmacol
; 12(11): 1626-1639, 2023 Nov.
Article
in English
| MEDLINE | ID: mdl-36793223
6.
MEN1309/OBT076, a First-In-Class Antibody-Drug Conjugate Targeting CD205 in Solid Tumors.
Mol Cancer Ther
; 18(9): 1533-1543, 2019 09.
Article
in English
| MEDLINE | ID: mdl-31227646
7.
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.
Oncotarget
; 7(4): 4570-83, 2016 Jan 26.
Article
in English
| MEDLINE | ID: mdl-26717037
8.
Molecular mechanism of PdxR a transcriptional activator involved in the regulation of vitamin B6 biosynthesis in the probiotic bacterium Bacillus clausii.
FEBS J
; 282(15): 2966-84, 2015 Aug.
Article
in English
| MEDLINE | ID: mdl-26059598
9.
How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.
FEBS J
; 282(7): 1225-41, 2015 Apr.
Article
in English
| MEDLINE | ID: mdl-25619277
10.
Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.
ChemMedChem
; 10(3): 490-7, 2015 Mar.
Article
in English
| MEDLINE | ID: mdl-25677305
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