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1.

High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation.

Robitaille, Karine; Rourke, Jillian L; McBane, Joanne E; Fu, Accalia; Baird, Stephen; Du, Qiujiang; Kin, Tatsuya; Shapiro, A M James; Screaton, Robert A.

J Biol Chem ; 291(9): 4614-25, 2016 Feb 26.

Article in English | MEDLINE | ID: mdl-26740620

2.

LKB1 couples glucose metabolism to insulin secretion in mice.

Fu, Accalia; Robitaille, Karine; Faubert, Brandon; Reeks, Courtney; Dai, Xiao-Qing; Hardy, Alexandre B; Sankar, Krishana S; Ogrel, Svetlana; Al-Dirbashi, Osama Y; Rocheleau, Jonathan V; Wheeler, Michael B; MacDonald, Patrick E; Jones, Russell; Screaton, Robert A.

Diabetologia ; 58(7): 1513-22, 2015 Jul.

Article in English | MEDLINE | ID: mdl-25874445

3.

Mitochondrial bioenergetics, metabolism, and beyond in pancreatic ß-cells and diabetes.

Rivera Nieves, Alejandra María; Wauford, Brian Michael; Fu, Accalia.

Front Mol Biosci ; 11: 1354199, 2024.

Article in English | MEDLINE | ID: mdl-38404962

4.

Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion.

Mailloux, Ryan J; Fu, Accalia; Robson-Doucette, Christine; Allister, Emma M; Wheeler, Michael B; Screaton, Robert; Harper, Mary-Ellen.

J Biol Chem ; 287(47): 39673-85, 2012 Nov 16.

Article in English | MEDLINE | ID: mdl-23035124

5.

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2.

Jansson, Deidre; Ng, Andy Cheuk-Him; Fu, Accalia; Depatie, Chantal; Al Azzabi, Mufida; Screaton, Robert A.

Proc Natl Acad Sci U S A ; 105(29): 10161-6, 2008 Jul 22.

Article in English | MEDLINE | ID: mdl-18626018

6.

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets.

Fu, Accalia; van Rooyen, Lara; Evans, Lindsay; Armstrong, Nina; Avizonis, Daina; Kin, Tatsuya; Bird, Gregory H; Reddy, Anita; Chouchani, Edward T; Liesa-Roig, Marc; Walensky, Loren D; Shapiro, A M James; Danial, Nika N.

Cell Rep ; 37(8): 110037, 2021 11 23.

Article in English | MEDLINE | ID: mdl-34818536

7.

UCP1 governs liver extracellular succinate and inflammatory pathogenesis.

Mills, Evanna L; Harmon, Cathal; Jedrychowski, Mark P; Xiao, Haopeng; Garrity, Ryan; Tran, Nhien V; Bradshaw, Gary A; Fu, Accalia; Szpyt, John; Reddy, Anita; Prendeville, Hannah; Danial, Nika N; Gygi, Steven P; Lynch, Lydia; Chouchani, Edward T.

Nat Metab ; 3(5): 604-617, 2021 05.

Article in English | MEDLINE | ID: mdl-34002097

8.

Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.

Bird, Gregory H; Fu, Accalia; Escudero, Silvia; Godes, Marina; Opoku-Nsiah, Kwadwo; Wales, Thomas E; Cameron, Michael D; Engen, John R; Danial, Nika N; Walensky, Loren D.

ACS Chem Biol ; 15(6): 1340-1348, 2020 06 19.

Article in English | MEDLINE | ID: mdl-32348108

9.

CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.

Wang, Chih-Hao; Lundh, Morten; Fu, Accalia; Kriszt, Rókus; Huang, Tian Lian; Lynes, Matthew D; Leiria, Luiz O; Shamsi, Farnaz; Darcy, Justin; Greenwood, Bennett P; Narain, Niven R; Tolstikov, Vladimir; Smith, Kyle L; Emanuelli, Brice; Chang, Young-Tae; Hagen, Susan; Danial, Nika N; Kiebish, Michael A; Tseng, Yu-Hua.

Sci Transl Med ; 12(558)2020 08 26.

Article in English | MEDLINE | ID: mdl-32848096

10.

Glucose-dependent partitioning of arginine to the urea cycle protects ß-cells from inflammation.

Fu, Accalia; Alvarez-Perez, Juan Carlos; Avizonis, Daina; Kin, Tatsuya; Ficarro, Scott B; Choi, Dong Wook; Karakose, Esra; Badur, Mehmet G; Evans, Lindsay; Rosselot, Carolina; Bridon, Gaelle; Bird, Gregory H; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Kamphorst, Jurre J; Stewart, Andrew F; James Shapiro, A M; Marto, Jarrod A; Walensky, Loren D; Jones, Russell G; Garcia-Ocana, Adolfo; Danial, Nika N.

Nat Metab ; 2(5): 432-446, 2020 05.

Article in English | MEDLINE | ID: mdl-32694660

11.

A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells.

Mailloux, Ryan; Fu, Accalia; Florian, Maria; Petrov, Ivan; Chen, Qixuan; Coughlan, Melanie C; Laziyan, Mahemuti; Yan, Jin; Caldwell, Don; Patry, Dominique; Lalande, Michelle; Wang, Gen-Sheng; Willmore, William; Jin, Xiaolei.

Toxicology ; 334: 81-93, 2015 Aug 06.

Article in English | MEDLINE | ID: mdl-26066519

12.

Phospho-BAD BH3 mimicry protects ß cells and restores functional ß cell mass in diabetes.

Ljubicic, Sanda; Polak, Klaudia; Fu, Accalia; Wiwczar, Jessica; Szlyk, Benjamin; Chang, Yigang; Alvarez-Perez, Juan C; Bird, Gregory H; Walensky, Loren D; Garcia-Ocaña, Adolfo; Danial, Nika N.

Cell Rep ; 10(4): 497-504, 2015 Feb 03.

Article in English | MEDLINE | ID: mdl-25640178

13.

Role of the SIK2-p35-PJA2 complex in pancreatic ß-cell functional compensation.

Sakamaki, Jun-Ichi; Fu, Accalia; Reeks, Courtney; Baird, Stephen; Depatie, Chantal; Al Azzabi, Mufida; Bardeesy, Nabeel; Gingras, Anne-Claude; Yee, Siu-Pok; Screaton, Robert A.

Nat Cell Biol ; 16(3): 234-44, 2014 Mar.

Article in English | MEDLINE | ID: mdl-24561619

14.

Grasping for aspartate in tumour metabolism.

Fu, Accalia; Danial, Nika N.

Nat Cell Biol ; 20(7): 738-739, 2018 07.

Article in English | MEDLINE | ID: mdl-29941932

15.

CRTC2 is required for ß-cell function and proliferation.

Eberhard, Chandra E; Fu, Accalia; Reeks, Courtney; Screaton, Robert A.

Endocrinology ; 154(7): 2308-17, 2013 Jul.

Article in English | MEDLINE | ID: mdl-23677932

16.

Role of AMPK in pancreatic beta cell function.

Fu, Accalia; Eberhard, Chandra E; Screaton, Robert A.

Mol Cell Endocrinol ; 366(2): 127-34, 2013 Feb 25.

Article in English | MEDLINE | ID: mdl-22766107

17.

Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels.

Phu, Do Thanh; Wallbach, Manuel; Depatie, Chantal; Fu, Accalia; Screaton, Robert A; Oetjen, Elke.

Cell Signal ; 23(2): 344-53, 2011 Feb.

Article in English | MEDLINE | ID: mdl-20940047

18.

Depletion of intranuclear rodlets in mouse models of diabetes.

Milman, Pavel; Fu, Accalia; Screaton, Robert A; Woulfe, John M.

Endocr Pathol ; 21(4): 230-5, 2010 Dec.

Article in English | MEDLINE | ID: mdl-20922502

19.

Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice.

Fu, Accalia; Ng, Andy Cheuk-Him; Depatie, Chantal; Wijesekara, Nadeeja; He, Ying; Wang, Gen-Sheng; Bardeesy, Nabeel; Scott, Fraser W; Touyz, Rhian M; Wheeler, Michael B; Screaton, Robert A.

Cell Metab ; 10(4): 285-95, 2009 Oct.

Article in English | MEDLINE | ID: mdl-19808021

20.

Using kinomics to delineate signaling pathways: control of CRTC2/TORC2 by the AMPK family.

Fu, Accalia; Screaton, Robert A.

Cell Cycle ; 7(24): 3823-8, 2008 Dec 15.

Article in English | MEDLINE | ID: mdl-19098422

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