Search | VHL Search Portal

1.

Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy.

Chen, Jonathan H; Nieman, Linda T; Spurrell, Maxwell; Jorgji, Vjola; Elmelech, Liad; Richieri, Peter; Xu, Katherine H; Madhu, Roopa; Parikh, Milan; Zamora, Izabella; Mehta, Arnav; Nabel, Christopher S; Freeman, Samuel S; Pirl, Joshua D; Lu, Chenyue; Meador, Catherine B; Barth, Jaimie L; Sakhi, Mustafa; Tang, Alexander L; Sarkizova, Siranush; Price, Colles; Fernandez, Nicolas F; Emanuel, George; He, Jiang; Van Raay, Katrina; Reeves, Jason W; Yizhak, Keren; Hofree, Matan; Shih, Angela; Sade-Feldman, Moshe; Boland, Genevieve M; Pelka, Karin; Aryee, Martin J; Mino-Kenudson, Mari; Gainor, Justin F; Korsunsky, Ilya; Hacohen, Nir.

Nat Immunol ; 25(4): 644-658, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38503922

2.

Therapy-induced APOBEC3A drives evolution of persistent cancer cells.

Isozaki, Hideko; Sakhtemani, Ramin; Abbasi, Ammal; Nikpour, Naveed; Stanzione, Marcello; Oh, Sunwoo; Langenbucher, Adam; Monroe, Susanna; Su, Wenjia; Cabanos, Heidie Frisco; Siddiqui, Faria M; Phan, Nicole; Jalili, Pégah; Timonina, Daria; Bilton, Samantha; Gomez-Caraballo, Maria; Archibald, Hannah L; Nangia, Varuna; Dionne, Kristin; Riley, Amanda; Lawlor, Matthew; Banwait, Mandeep Kaur; Cobb, Rosemary G; Zou, Lee; Dyson, Nicholas J; Ott, Christopher J; Benes, Cyril; Getz, Gad; Chan, Chang S; Shaw, Alice T; Gainor, Justin F; Lin, Jessica J; Sequist, Lecia V; Piotrowska, Zofia; Yeap, Beow Y; Engelman, Jeffrey A; Lee, Jake June-Koo; Maruvka, Yosef E; Buisson, Rémi; Lawrence, Michael S; Hata, Aaron N.

Nature ; 620(7973): 393-401, 2023 Aug.

Article in English | MEDLINE | ID: mdl-37407818

3.

Mechanistic model for booster doses effectiveness in healthy, cancer, and immunosuppressed patients infected with SARS-CoV-2.

Voutouri, Chrysovalantis; Hardin, C Corey; Naranbhai, Vivek; Nikmaneshi, Mohammad R; Khandekar, Melin J; Gainor, Justin F; Stylianopoulos, Triantafyllos; Munn, Lance L; Jain, Rakesh K.

Proc Natl Acad Sci U S A ; 120(3): e2211132120, 2023 01 17.

Article in English | MEDLINE | ID: mdl-36623200

4.

Pralsetinib in patients with RET fusion-positive non-small-cell lung cancer: A plain language summary of the ARROW study.

Griesinger, Frank; Curigliano, Giuseppe; Subbiah, Vivek; Baik, Christina S; Tan, Daniel Sw; Lee, Dae H; Misch, Daniel; Garralda, Elena; Kim, Dong-Wan; van der Wekken, Anthonie J; Gainor, Justin F; Paz-Ares, Luis; Liu, Stephen V; Kalemkerian, Gregory P; Bowles, Daniel W; Mansfield, Aaron S; Lin, Jessica J; Smoljanovic, Vlatka; Rahman, Ahmadur; Zalutskaya, Alena; Louie-Gao, Melinda; Boral, Andy L; Mazières, Julien.

Future Oncol ; 20(6): 297-306, 2024 Feb.

Article in English | MEDLINE | ID: mdl-37916501

5.

Lung cancer.

Thai, Alesha A; Solomon, Benjamin J; Sequist, Lecia V; Gainor, Justin F; Heist, Rebecca S.

Lancet ; 398(10299): 535-554, 2021 08 07.

Article in English | MEDLINE | ID: mdl-34273294

6.

Phase II Study of Cabozantinib in Patients With Bone Metastasis.

Choy, Edwin; Cote, Gregory M; Michaelson, M Dror; Wirth, Lori; Gainor, Justin F; Muzikansky, Alona; Sequist, Lecia V; Sullivan, Ryan J; Fidias, Panagiotis M; Shaw, Alice; Heist, Rebecca S.

Oncologist ; 27(7): 600-606, 2022 07 05.

Article in English | MEDLINE | ID: mdl-35524758

7.

Lymphocyte-activation gene 3 in non-small-cell lung carcinomas: correlations with clinicopathologic features and prognostic significance.

Shepherd, Daniel J; Tabb, Elisabeth S; Kunitoki, Keiko; Zhang, M Lisa; Kem, Marina; Barth, Jaimie; Qualls, David A; Mooradian, Meghan J; Gainor, Justin F; Mino-Kenudson, Mari; Hung, Yin P.

Mod Pathol ; 35(5): 615-624, 2022 05.

Article in English | MEDLINE | ID: mdl-34880448

8.

Lung-RADS Category 3 and 4 Nodules on Lung Cancer Screening in Clinical Practice.

Mendoza, Dexter P; Petranovic, Milena; Som, Avik; Wu, Markus Y; Park, Esther Y; Zhang, Eric W; Archer, John M; McDermott, Shaunagh; Khandekar, Melin; Lanuti, Michael; Gainor, Justin F; Lennes, Inga T; Shepard, Jo-Anne O; Digumarthy, Subba R.

AJR Am J Roentgenol ; 219(1): 55-65, 2022 07.

Article in English | MEDLINE | ID: mdl-35080453

9.

A combinatorial strategy for treating KRAS-mutant lung cancer.

Manchado, Eusebio; Weissmueller, Susann; Morris, John P; Chen, Chi-Chao; Wullenkord, Ramona; Lujambio, Amaia; de Stanchina, Elisa; Poirier, John T; Gainor, Justin F; Corcoran, Ryan B; Engelman, Jeffrey A; Rudin, Charles M; Rosen, Neal; Lowe, Scott W.

Nature ; 534(7609): 647-51, 2016 06 30.

Article in English | MEDLINE | ID: mdl-27338794

10.

Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study.

Lakhani, Nehal J; Chow, Laura Q M; Gainor, Justin F; LoRusso, Patricia; Lee, Keun-Wook; Chung, Hyun Cheol; Lee, Jeeyun; Bang, Yung-Jue; Hodi, Frank Stephen; Kim, Won Seog; Santana-Davila, Rafael; Fanning, Philip; Squifflet, Pierre; Jin, Feng; Kuo, Tracy C; Wan, Hong I; Pons, Jaume; Randolph, Sophia S; Messersmith, Wells A.

Lancet Oncol ; 22(12): 1740-1751, 2021 12.

Article in English | MEDLINE | ID: mdl-34793719

11.

Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study.

Gainor, Justin F; Curigliano, Giuseppe; Kim, Dong-Wan; Lee, Dae Ho; Besse, Benjamin; Baik, Christina S; Doebele, Robert C; Cassier, Philippe A; Lopes, Gilberto; Tan, Daniel S W; Garralda, Elena; Paz-Ares, Luis G; Cho, Byoung Chul; Gadgeel, Shirish M; Thomas, Michael; Liu, Stephen V; Taylor, Matthew H; Mansfield, Aaron S; Zhu, Viola W; Clifford, Corinne; Zhang, Hui; Palmer, Michael; Green, Jennifer; Turner, Christopher D; Subbiah, Vivek.

Lancet Oncol ; 22(7): 959-969, 2021 07.

Article in English | MEDLINE | ID: mdl-34118197

12.

An early look at selective RET inhibitor resistance: new challenges and opportunities.

Lin, Jessica J; Gainor, Justin F.

Br J Cancer ; 124(11): 1757-1758, 2021 05.

Article in English | MEDLINE | ID: mdl-33758332

13.

Temporal Trends in Inpatient Oncology Census Before and During the COVID-19 Pandemic and Rates of Nosocomial COVID-19 Among Patients with Cancer at a Large Academic Center.

Zubiri, Leyre; Rosovsky, Rachel P; Mooradian, Meghan J; Piper-Vallillo, A J; Gainor, Justin F; Sullivan, Ryan J; Marte, Daniel; Boland, Genevieve M; Gao, Xin; Hochberg, Ephraim P; Ryan, David P; McEwen, Corey; Mai, Minh; Sharova, Tanya; Soumerai, Tara E; Bardia, Aditya; Reynolds, Kerry L.

Oncologist ; 26(8): e1427-e1433, 2021 08.

Article in English | MEDLINE | ID: mdl-33932247

14.

Immune Checkpoint Inhibitors - The Need for Innovation.

Johnson, P Connor; Gainor, Justin F; Sullivan, Ryan J; Longo, Dan L; Chabner, Bruce.

N Engl J Med ; 388(16): 1529-1532, 2023 Apr 20.

Article in English | MEDLINE | ID: mdl-37075146

15.

Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial.

Shu, Catherine A; Gainor, Justin F; Awad, Mark M; Chiuzan, Codruta; Grigg, Claud M; Pabani, Aliyah; Garofano, Robert F; Stoopler, Mark B; Cheng, Simon K; White, Abby; Lanuti, Michael; D'Ovidio, Frank; Bacchetta, Matthew; Sonett, Joshua R; Saqi, Anjali; Rizvi, Naiyer A.

Lancet Oncol ; 21(6): 786-795, 2020 06.

Article in English | MEDLINE | ID: mdl-32386568

16.

Performance status and end-of-life care among adults with non-small cell lung cancer receiving immune checkpoint inhibitors.

Petrillo, Laura A; El-Jawahri, Areej; Nipp, Ryan D; Lichtenstein, Morgan R L; Durbin, Sienna M; Reynolds, Kerry L; Greer, Joseph A; Temel, Jennifer S; Gainor, Justin F.

Cancer ; 126(10): 2288-2295, 2020 05 15.

Article in English | MEDLINE | ID: mdl-32142165

17.

Cost-effectiveness of immune checkpoint inhibitors for microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer.

Chu, Jacqueline N; Choi, Jin; Ostvar, Sassan; Torchia, James A; Reynolds, Kerry Lynn; Tramontano, Angela; Gainor, Justin F; Chung, Daniel C; Clark, Jeffrey W; Hur, Chin.

Cancer ; 125(2): 278-289, 2019 01 15.

Article in English | MEDLINE | ID: mdl-30343509

18.

Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.

Shaw, Alice T; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F; Bergqvist, Simon; Brooun, Alexei; Burke, Benjamin J; Deng, Ya-Li; Liu, Wei; Dardaei, Leila; Frias, Rosa L; Schultz, Kate R; Logan, Jennifer; James, Leonard P; Smeal, Tod; Timofeevski, Sergei; Katayama, Ryohei; Iafrate, A John; Le, Long; McTigue, Michele; Getz, Gad; Johnson, Ted W; Engelman, Jeffrey A.

N Engl J Med ; 374(1): 54-61, 2016 Jan 07.

Article in English | MEDLINE | ID: mdl-26698910

19.

Differential expression of PD-L1 and IDO1 in association with the immune microenvironment in resected lung adenocarcinomas.

Zhang, M Lisa; Kem, Marina; Mooradian, Meghan J; Eliane, Jean-Pierre; Huynh, Tiffany G; Iafrate, A John; Gainor, Justin F; Mino-Kenudson, Mari.

Mod Pathol ; 32(4): 511-523, 2019 04.

Article in English | MEDLINE | ID: mdl-30367104

20.

Lorlatinib in non-small-cell lung cancer with ALK or ROS1 rearrangement: an international, multicentre, open-label, single-arm first-in-man phase 1 trial.

Shaw, Alice T; Felip, Enriqueta; Bauer, Todd M; Besse, Benjamin; Navarro, Alejandro; Postel-Vinay, Sophie; Gainor, Justin F; Johnson, Melissa; Dietrich, Jorg; James, Leonard P; Clancy, Jill S; Chen, Joseph; Martini, Jean-François; Abbattista, Antonello; Solomon, Benjamin J.

Lancet Oncol ; 18(12): 1590-1599, 2017 12.

Article in English | MEDLINE | ID: mdl-29074098

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: