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1.

Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling.

Gao, Hua; Chakraborty, Goutam; Zhang, Zhanguo; Akalay, Intissar; Gadiya, Mayur; Gao, Yaquan; Sinha, Surajit; Hu, Jian; Jiang, Cizhong; Akram, Muzaffar; Brogi, Edi; Leitinger, Birgit; Giancotti, Filippo G.

Cell ; 166(1): 47-62, 2016 Jun 30.

Article in English | MEDLINE | ID: mdl-27368100

2.

Mechanisms governing metastatic dormancy and reactivation.

Giancotti, Filippo G.

Cell ; 155(4): 750-64, 2013 Nov 07.

Article in English | MEDLINE | ID: mdl-24209616

3.

The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.

Gao, Hua; Chakraborty, Goutam; Lee-Lim, Ai Ping; Mo, Qianxing; Decker, Markus; Vonica, Alin; Shen, Ronglai; Brogi, Edi; Brivanlou, Ali H; Giancotti, Filippo G.

Cell ; 150(4): 764-79, 2012 Aug 17.

Article in English | MEDLINE | ID: mdl-22901808

4.

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.

Li, Wei; You, Liru; Cooper, Jonathan; Schiavon, Gaia; Pepe-Caprio, Angela; Zhou, Lu; Ishii, Ryohei; Giovannini, Marco; Hanemann, C Oliver; Long, Stephen B; Erdjument-Bromage, Hediye; Zhou, Pengbo; Tempst, Paul; Giancotti, Filippo G.

Cell ; 140(4): 477-90, 2010 Feb 19.

Article in English | MEDLINE | ID: mdl-20178741

5.

Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation.

Gao, Hua; Chakraborty, Goutam; Lee-Lim, Ai Ping; Mavrakis, Konstantinos J; Wendel, Hans-Guido; Giancotti, Filippo G.

Proc Natl Acad Sci U S A ; 111(46): 16532-7, 2014 Nov 18.

Article in English | MEDLINE | ID: mdl-25378704

6.

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.

Li, Wei; Cooper, Jonathan; Karajannis, Matthias A; Giancotti, Filippo G.

EMBO Rep ; 13(3): 204-15, 2012 Mar.

Article in English | MEDLINE | ID: mdl-22482125

7.

Noncanonical Activity of Med4 as a Gatekeeper of Metastasis through Epigenetic Control of Integrin Signaling.

Bae, Seong-Yeon; Chen, Yi; Chen, Hong; Kumar, Dhiraj; Karaiskos, Spyros; Xu, Jane; Lu, Chao; Viny, Aaron D; Giancotti, Filippo G.

bioRxiv ; 2024 Jan 10.

Article in English | MEDLINE | ID: mdl-38014033

8.

LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells.

Kumar, Dhiraj; Gurrapu, Sreeharsha; Wang, Yan; Bae, Seong-Yeon; Pandey, Poonam R; Chen, Hong; Mondal, Jayanta; Han, Hyunho; Wu, Chang-Jiun; Karaiskos, Spyros; Yang, Fei; Sahin, Aysegul; Wistuba, Ignacio I; Gao, Jianjun; Tripathy, Debasish; Gao, Hua; Izar, Benjamin; Giancotti, Filippo G.

Nat Cancer ; 5(2): 262-282, 2024 Feb.

Article in English | MEDLINE | ID: mdl-38195932

9.

STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response.

Patel, Bhakti; Zhou, Yifan; Babcock, Rachel L; Ma, Feiyang; Zal, M Anna; Kumar, Dhiraj; Medik, Yusra B; Kahn, Laura M; Pineda, Josué E; Park, Elizabeth M; Schneider, Sarah M; Tang, Ximing; Raso, Maria Gabriela; Jeter, Collene R; Zal, Tomasz; Clise-Dwyer, Karen; Keyomarsi, Khandan; Giancotti, Filippo G; Colla, Simona; Watowich, Stephanie S.

Leukemia ; 38(5): 1143-1155, 2024 May.

Article in English | MEDLINE | ID: mdl-38467768

10.

Metastatic colorectal cancer: mechanisms and emerging therapeutics.

Shin, Alice E; Giancotti, Filippo G; Rustgi, Anil K.

Trends Pharmacol Sci ; 44(4): 222-236, 2023 04.

Article in English | MEDLINE | ID: mdl-36828759

11.

STAT3 protects HSCs from intrinsic interferon signaling and loss of long-term blood-forming activity.

Patel, Bhakti; Zhou, Yifan; Babcock, Rachel L; Ma, Feiyang; Zal, Malgorzata A; Kumar, Dhiraj; Medik, Yusra B; Kahn, Laura M; Pineda, Josué E; Park, Elizabeth M; Tang, Ximing; Raso, Maria Gabriela; Zal, Tomasz; Clise-Dwyer, Karen; Giancotti, Filippo G; Colla, Simona; Watowich, Stephanie S.

bioRxiv ; 2023 Feb 11.

Article in English | MEDLINE | ID: mdl-36798265

12.

Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas.

Kuburich, Nick A; den Hollander, Petra; Castaneda, Maria; Pietilä, Mika; Tang, Ximing; Batra, Harsh; Martínez-Peña, Francisco; Visal, Tanvi H; Zhou, Tieling; Demestichas, Breanna R; Dontula, Ritesh V; Liu, Jojo Y; Maddela, Joanna Joyce; Padmanabhan, Reethi S; Phi, Lan Thi Hanh; Rosolen, Matthew J; Sabapathy, Thiru; Kumar, Dhiraj; Giancotti, Filippo G; Lairson, Luke L; Raso, Maria Gabriela; Soundararajan, Rama; Mani, Sendurai A.

Cell Rep ; 42(12): 113470, 2023 12 26.

Article in English | MEDLINE | ID: mdl-37979166

13.

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

Pylayeva, Yuliya; Gillen, Kelly M; Gerald, William; Beggs, Hilary E; Reichardt, Louis F; Giancotti, Filippo G.

J Clin Invest ; 119(2): 252-66, 2009 Feb.

Article in English | MEDLINE | ID: mdl-19147981

14.

Guido Tarone, Ph.D. (1951-2015).

Giancotti, Filippo G; Fässler, Reinhard.

J Cell Sci ; 128(16): 2955-6, 2015 Aug 15.

Article in English | MEDLINE | ID: mdl-26495456

15.

Integrin beta4 signaling promotes tumor angiogenesis.

Nikolopoulos, Sotiris N; Blaikie, Pamela; Yoshioka, Toshiaki; Guo, Wenjun; Giancotti, Filippo G.

Cancer Cell ; 6(5): 471-83, 2004 Nov.

Article in English | MEDLINE | ID: mdl-15542431

16.

The Hippo pathway mediates Semaphorin signaling.

Meng, Zhipeng; Li, Fu-Long; Fang, Cao; Yeoman, Benjamin; Qiu, Yunjiang; Wang, Ying; Cai, Xiaomin; Lin, Kimberly C; Yang, Di; Luo, Min; Fu, Vivian; Ma, Xiaoxiao; Diao, Yarui; Giancotti, Filippo G; Ren, Bing; Engler, Adam J; Guan, Kun-Liang.

Sci Adv ; 8(21): eabl9806, 2022 May 27.

Article in English | MEDLINE | ID: mdl-35613278

17.

Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis.

Han, Hyunho; Wang, Yan; Curto, Josue; Gurrapu, Sreeharsha; Laudato, Sara; Rumandla, Alekya; Chakraborty, Goutam; Wang, Xiaobo; Chen, Hong; Jiang, Yan; Kumar, Dhiraj; Caggiano, Emily G; Capogiri, Monica; Zhang, Boyu; Ji, Yan; Maity, Sankar N; Hu, Min; Bai, Shanshan; Aparicio, Ana M; Efstathiou, Eleni; Logothetis, Christopher J; Navin, Nicholas; Navone, Nora M; Chen, Yu; Giancotti, Filippo G.

Cell Rep ; 39(1): 110595, 2022 04 05.

Article in English | MEDLINE | ID: mdl-35385726

18.

Back to the future: proceedings from the 2010 NF Conference.

Huson, Susan M; Acosta, Maria T; Belzberg, Allan J; Bernards, Andre; Chernoff, Jonathan; Cichowski, Karen; Gareth Evans, D; Ferner, Rosalie E; Giovannini, Marco; Korf, Bruce R; Listernick, Robert; North, Kathryn N; Packer, Roger J; Parada, Luis F; Peltonen, Juha; Ramesh, Vijaya; Reilly, Karlyne M; Risner, John W; Schorry, Elizabeth K; Upadhyaya, Meena; Viskochil, David H; Zhu, Yuan; Hunter-Schaedle, Kim; Giancotti, Filippo G.

Am J Med Genet A ; 155A(2): 307-21, 2011 Feb.

Article in English | MEDLINE | ID: mdl-21271647

19.

Prostate epithelial genes define therapy-relevant prostate cancer molecular subtype.

Han, Hyunho; Lee, Hyung Ho; Choi, Kwibok; Moon, Young Jun; Heo, Ji Eun; Ham, Won Sik; Jang, Won Sik; Rha, Koon Ho; Cho, Nam Hoon; Giancotti, Filippo G; Choi, Young-Deuk.

Prostate Cancer Prostatic Dis ; 24(4): 1080-1092, 2021 12.

Article in English | MEDLINE | ID: mdl-33903734

20.

Phase 0 Clinical Trial of Everolimus in Patients with Vestibular Schwannoma or Meningioma.

Karajannis, Matthias A; Mauguen, Audrey; Maloku, Ekrem; Xu, Qingwen; Dunbar, Erin M; Plotkin, Scott R; Yaffee, Anna; Wang, Shiyang; Roland, J Thomas; Sen, Chandranath; Placantonakis, Dimitris G; Golfinos, John G; Allen, Jeffrey C; Vitanza, Nicholas A; Chiriboga, Luis A; Schneider, Robert J; Deng, Jingjing; Neubert, Thomas A; Goldberg, Judith D; Zagzag, David; Giancotti, Filippo G; Blakeley, Jaishri O.

Mol Cancer Ther ; 20(9): 1584-1591, 2021 09.

Article in English | MEDLINE | ID: mdl-34224367

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