1.
Exp Dermatol
; 31(5): 821-822, 2022 05.
Article
in English
| MEDLINE
| ID: mdl-34816495
ABSTRACT
The role of Malassezia yeasts in dandruff and seborrheic dermatitis is unclear; however, antifungal therapy with ketoconazole is commonly used. We propose that ketoconazole shifts skin lipid profile, affects Malassezia lipid metabolism and favours biotin-producing bacteria. Biotin regulates inflammatory response and cell proliferation, contributing to symptom improvement.