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1.
Ear Hear ; 44(3): 588-602, 2023.
Article in English | MEDLINE | ID: mdl-36575571

ABSTRACT

OBJECTIVES: Limited evidence exists for the use of rerouting devices in children with severe-to-profound unilateral sensorineural hearing loss. Many laboratory studies to date have evaluated hearing-in-noise performance in specific target-masker spatial configurations within a small group of participants and with only a subset of available hearing devices. In the present study, the efficacy of all major types of nonsurgical devices was evaluated within a larger group of pediatric subjects on a challenging speech-in-noise recognition task. DESIGN: Children (7-18 years) with unaided severe-to-profound unilateral hearing loss (UHL' n = 36) or bilateral normal hearing (NH, n = 36) participated in the present study. The signal-to-noise ratio (SNR) required for 50% speech understanding (SNR-50) was measured using BKB sentences in the presence of proprietary restaurant noise (R-SPACE BSIN-R) in the R-SPACE Sound System. Subjects listened under 2 target/masker spatial configurations. The target signal was directed toward subjects' NH or hearing-impaired ear (45º azimuth), while the interfering restaurant noise masker was presented from the remaining 7 loudspeakers encircling the subject, spaced every 45º. Head position was fixed during testing. The presentation level of target sentences and masking noise varied over time to estimate the SNR-50 (dB). The following devices were tested in all participants with severe-to-profound UHL: air conduction (AC) contralateral routing of signal (CROS), bone conduction (BC) CROS fitted on a headband with and without the use of remote microphone (RM), and an ear-level RM hearing assistance technology (HAT) system. RESULTS: As a group, participants with severe-to-profound UHL performed best when the target signal was directed toward their NH ear. Across listening conditions, there was an average 8.5 dB improvement in SNR-50 by simply orienting the NH ear toward the target signal. When unaided, participants with severe-to-profound UHL performed as well as participants with NH when the target signal was directed toward the NH ear. Performance was negatively affected by AC CROS when the target signal was directed toward the NH ear, whereas no statistically significant change in performance was observed when using BC CROS. When the target signal was directed toward participants' hearing-impaired ear, all tested devices improved SNR-50 compared with the unaided condition, with small improvements (1-2 dB) observed with CROS devices and the largest improvement (9 dB) gained with the personal ear-level RM HAT system. No added benefit nor decrement was observed when RM was added to BC CROS using a 50/50 mixing ratio when the target was directed toward the impaired ear. CONCLUSIONS: In a challenging listening environment with diffuse restaurant noise, SNR-50 was most improved in the study sample when using a personal ear-level RM HAT system. Although tested rerouting devices offered measurable improvement in performance (1-2 dB in SNR-50) when the target was directed to the impaired ear, benefit may be offset by a detriment in performance in the opposing condition. Findings continue to support use of RM HAT for children with severe-to-profound UHL in adverse listening environments, when there is one primary talker of interest, to ensure advantageous SNRs.


Subject(s)
Hearing Aids , Hearing Loss, Unilateral , Speech Perception , Humans , Child , Speech , Hearing , Noise
2.
Ear Hear ; 43(2): 255-267, 2022.
Article in English | MEDLINE | ID: mdl-35213890

ABSTRACT

More children with single-sided deafness (SSD) are receiving cochlear implants (CIs) due to the expansion of CI indications. This unique group of pediatric patients has different needs than the typical recipient with bilateral deafness and requires special consideration and care. The goal of cochlear implantation in these children is to provide bilateral input to encourage the development of binaural hearing. Considerations for candidacy and follow-up care should reflect and measure these goals. The purpose of this document is to review the current evidence and provide guidance for CI candidacy, evaluation, and management in children with SSD.


Subject(s)
Cochlear Implantation , Cochlear Implants , Deafness , Hearing Loss, Unilateral , Speech Perception , Child , Deafness/rehabilitation , Hearing , Hearing Loss, Unilateral/rehabilitation , Humans
3.
Ear Hear ; 42(2): 334-342, 2021.
Article in English | MEDLINE | ID: mdl-32826503

ABSTRACT

OBJECTIVES: To identify the incidence of specific abnormal impedance patterns or electrode faults, and determine their implication and significance, in a pediatric population of cochlear implant recipients. DESIGN: Nine hundred fifty-six cochlear implant devices (621 recipients) were included in this retrospective study. Devices were included if the implantation surgery was performed at our tertiary care hospital, and the recipient was 21 years of age or younger at the time the device was implanted. Device models incapable of producing impedance measures by telemetry were excluded from the study. Individual devices with abnormal impedance measures indicating an open circuit (OC), short circuit (SC), or partial short circuit (partial SC) were included in the study, unless these abnormalities occurred only in the OR and not postoperatively. Device and patient characteristics were examined to determine their relationship to increased incidence of electrode faults or atypical patterns. RESULTS: The incidence of software-identified electrode faults in our exclusively pediatric population was similar to that reported in the literature containing mixed-age cohorts. Nine percent of devices experienced at least one OC or one pair of SCs. Although higher incidence of these faults was seen in some specific device models, the long-term average of these faults was equivalent across manufacturers. No factors examined in this study increased the likelihood of experiencing a software-identified electrode fault. Within the study period under examination (October 1997 to March 2018), partial SCs (presenting as zig-zag or low-flat impedance patterns) were only observed in Cochlear devices. While the incidence of these partial SC abnormalities (non-software-identified faults) was 6% across all models of Cochlear devices, the CI24RCS experienced the highest incidence of partial SCs. The incidence of this pattern was lower in models manufactured after CI24RCS. CONCLUSIONS: This study provides incidence of various cochlear implant electrode impedance abnormalities across a large cohort of pediatric recipients. The incidence of all electrode abnormalities was relatively low, particularly partial SCs, which are less well recognized and not currently identified by clinician-accessible software. Incidence of software-identified electrode faults (i.e., SCs and OCs) in our pediatric-only study is similar to the incidence reported in other mixed-population and adult-only studies. These common electrode faults generally are not associated with device failure, and clinicians should feel comfortable reassuring families that an individual electrode fault does not imply an impending device failure. Conversely, those atypical impedance patterns not currently flagged by the programming software as abnormal, but visible to the clinician's eye (i.e., partial SCs in zig-zag or low-flat patterns), have a higher likelihood of device damage and failure. Performance in patients with electrode arrays exhibiting these atypical patterns should be closely monitored for any functional decrement, and proactively managed to maintain performance whenever possible.


Subject(s)
Cochlear Implantation , Cochlear Implants , Adolescent , Child , Electrodes, Implanted , Humans , Incidence , Retrospective Studies , Young Adult
4.
Behav Genet ; 49(2): 175-186, 2019 03.
Article in English | MEDLINE | ID: mdl-30656439

ABSTRACT

Virtuous character development in children is correlated with parenting behavior, but the role of genetic influences in this association has not been examined. Using a longitudinal twin/sibling study (N = 720; Time 1 (T1) Mage = 12-14 years, Time 3 (T3) Mage = 25-27 years), the current report examines associations among parental negativity/positivity and offspring responsibility during adolescence, and subsequent young adult conscientiousness. Findings indicate that associations among parental negativity and offspring virtuous character during adolescence and young adulthood are due primarily to heritable influences. In contrast, the association between concurrent parental positivity and adolescent responsibility was due primarily to heritable and shared environmental influences. These findings underscore the contributions of heritable influences to the associations between parenting and virtuous character that have previously been assumed to be only environmentally influenced, emphasizing the complexity of mechanisms involved in the development of virtuous character.


Subject(s)
Inheritance Patterns/genetics , Socialization , Virtues , Female , Humans , Male , Models, Psychological , Parenting , Phenotype
5.
Ear Hear ; 40(4): 887-904, 2019.
Article in English | MEDLINE | ID: mdl-30418282

ABSTRACT

OBJECTIVES: (1) Measure sentence recognition in co-located and spatially separated target and masker configurations in school-aged children with unilateral hearing loss (UHL) and with normal hearing (NH). (2) Compare self-reported hearing-related quality-of-life (QoL) scores in school-aged children with UHL and NH. DESIGN: Listeners were school-aged children (6 to 12 yrs) with permanent UHL (n = 41) or NH (n = 35) and adults with NH (n = 23). Sentence reception thresholds (SRTs) were measured using Hearing In Noise Test-Children sentences in quiet and in the presence of 2-talker child babble or a speech-shaped noise masker in target/masker spatial configurations: 0/0, 0/-60, 0/+60, or 0/±60 degrees azimuth. Maskers were presented at a fixed level of 55 dBA, while the level of the target sentences varied adaptively to estimate the SRT. Hearing-related QoL was measured using the Hearing Environments and Reflection on Quality of Life (HEAR-QL-26) questionnaire for child subjects. RESULTS: As a group, subjects with unaided UHL had higher (poorer) SRTs than age-matched peers with NH in all listening conditions. Effects of age, masker type, and spatial configuration of target and masker signals were found. Spatial release from masking was significantly reduced in conditions where the masker was directed toward UHL subjects' normal-hearing ear. Hearing-related QoL scores were significantly poorer in subjects with UHL compared to those with NH. Degree of UHL, as measured by four-frequency pure-tone average, was significantly correlated with SRTs only in the two conditions where the masker was directed towards subjects' normal-hearing ear, although the unaided Speech Intelligibility Index at 65 dB SPL was significantly correlated with SRTs in four conditions, some of which directed the masker to the impaired ear or both ears. Neither pure-tone average nor unaided Speech Intelligibility Index was correlated with QoL scores. CONCLUSIONS: As a group, school-aged children with UHL showed substantial reductions in masked speech perception and hearing-related QoL, irrespective of sex, laterality of hearing loss, and degree of hearing loss. While some children demonstrated normal or near-normal performance in certain listening conditions, a disproportionate number of thresholds fell in the poorest decile of the NH data. These findings add to the growing literature challenging the past assumption that one ear is "good enough."


Subject(s)
Hearing Loss, Unilateral/physiopathology , Hearing Loss, Unilateral/psychology , Noise , Quality of Life , Speech Perception , Adult , Audiometry, Pure-Tone , Case-Control Studies , Child , Female , Humans , Male , Middle Aged , Severity of Illness Index , Speech Reception Threshold Test , Young Adult
6.
Dev Psychopathol ; 31(5): 1633-1647, 2019 12.
Article in English | MEDLINE | ID: mdl-31439063

ABSTRACT

To advance research from Dishion and others on associations between parenting and peer problems across childhood, we used a sample of 177 sibling pairs reared apart since birth (because of adoption of one of the siblings) to examine associations between parental hostility and children's peer problems when children were ages 7 and 9.5 years (n = 329 children). We extended conventional cross-lagged parent-peer models by incorporating child inhibitory control as an additional predictor and examining genetic contributions via birth mother psychopathology. Path models indicated a cross-lagged association from parental hostility to later peer problems. When child inhibitory control was included, birth mother internalizing symptoms were associated with poorer child inhibitory control, which was associated with more parental hostility and peer problems. The cross-lagged paths from parental hostility to peer problems were no longer significant in the full model. Multigroup analyses revealed that the path from birth mother internalizing symptoms to child inhibitory control was significantly higher for birth parent-reared children, indicating the possible contribution of passive gene-environment correlation to this association. Exploratory analyses suggested that each child's unique rearing context contributed to his or her inhibitory control and peer behavior. Implications for the development of evidence-based interventions are discussed.


Subject(s)
Child Rearing/psychology , Friends/psychology , Parenting/psychology , Peer Group , Siblings/psychology , Child , Female , Hostility , Humans , Male , Problem Behavior/psychology
7.
Child Welfare ; 97(5-6): 199-215, 2019.
Article in English | MEDLINE | ID: mdl-32308211

ABSTRACT

We investigated the prediction of young adult service utilization and trauma symptoms from adverse childhood experiences (ACEs) and adolescent mental health symptoms in young women with dual child welfare and juvenile justice system involvement. A sample of 166 females (ages 13 to 17) was followed to examine the transition to young adulthood. Path models indicated that more ACEs were associated with poorer adolescent mental health. Adolescent mental health symptoms were associated with more young adult trauma symptoms and service utilization. Implications for service providers and policy-makers are discussed.

8.
Prev Sci ; 19(1): 15-26, 2018 01.
Article in English | MEDLINE | ID: mdl-28150062

ABSTRACT

This study investigated the oxytocin receptor (OXTR) gene's moderation of associations between exposure to a substance misuse intervention, average peer substance use, and adolescents' own alcohol use during the 9th-grade. OXTR genetic risk was measured using five single nucleotide polymorphisms (SNPs), and peer substance use was based on youths' nominated closest friends' own reports of alcohol, cigarette, and marijuana use, based on data from the PROSPER project. Regression models revealed several findings. First, low OXTR risk was linked to affiliating with friends who reported less substance use in the intervention condition but not the control condition. Second, affiliating with high substance-using friends predicted youth alcohol risk regardless of OXTR risk or intervention condition. Third, although high OXTR risk youth in the intervention condition who associated with low substance-using friends reported somewhat higher alcohol use than comparable youth in the control group, the absolute level of alcohol use among these youth was still among the lowest in the sample.


Subject(s)
Peer Group , Receptors, Oxytocin/genetics , Underage Drinking/prevention & control , Adolescent , Child , Genetic Variation/genetics , Humans , Polymorphism, Single Nucleotide , Risk Assessment , Underage Drinking/statistics & numerical data
9.
J Acoust Soc Am ; 143(2): EL133, 2018 02.
Article in English | MEDLINE | ID: mdl-29495692

ABSTRACT

The precedence effect for transient sounds has been proposed to be based primarily on monaural processes, manifested by asymmetric temporal masking. This study explored the potential for monaural explanations with longer ("ongoing") sounds exhibiting the precedence effect. Transient stimuli were single lead-lag noise burst pairs; ongoing stimuli were trains of 63 burst pairs. Unlike with transients, monaural masking data for ongoing sounds showed no advantage for the lead, and are inconsistent with asymmetric audibility as an explanation for ongoing precedence. This result, along with supplementary measurements of interaural time discrimination, suggests different explanations for transient and ongoing precedence.


Subject(s)
Auditory Perception , Noise/adverse effects , Perceptual Masking , Acoustic Stimulation , Adult , Cues , Female , Humans , Male , Pitch Discrimination , Signal Detection, Psychological , Time Factors , Young Adult
10.
Subst Use Misuse ; 53(1): 114-127, 2018 01 02.
Article in English | MEDLINE | ID: mdl-28813187

ABSTRACT

BACKGROUND: Affiliating with 12-step groups appears to reduce relapse risk. By relying on between-person designs, extant research has been unable to examine daily mechanisms through which 12-step group affiliation contributes to recovery. OBJECTIVES: To examine the daily use and factor structure of the 12 steps and intrapersonal predictors and moderators of 12-step use. To determine whether the 12 steps were used in response to daily craving and, if so, which steps and in what contexts. METHODS: Data comprised 1304 end-of-day diary data entries from 55 young adults collected in 2008 from members of a college recovery community, combined with person-level baseline measures. Exploratory factor analysis examined the factor structure, and multi-level models examined both day-level and person-level predictors and moderators of step use, including meeting attendance, drug and alcohol dependence, social support, and coping strategies. RESULTS: Analyses produced two factors: Everyday steps, comprising surrender and maintenance steps, and action steps. Moderation analyses revealed that only action steps were significantly associated with craving, suggesting that craving can spur their use, but only among individuals pursuing certain general strategies for coping with stress: Separate median-split models produced significant associations between craving and action steps only among individuals high in avoidance, high in support-seeking, and/or low in problem-solving. Conclusions/Importance: This is the first study to empirically discern a 2-factor structure underlying the 12 steps, and to show that the two sets of steps are used in different contexts. The study also illustrates the value of person-centered approaches to recovery research and practice.


Subject(s)
Adaptation, Psychological , Craving , Patient Compliance/psychology , Self-Help Groups , Female , Humans , Male , Models, Psychological , Recurrence , Secondary Prevention/methods , Social Support , Students/psychology , Substance-Related Disorders/therapy , Universities , Young Adult
11.
J Pediatr Psychol ; 41(1): 37-45, 2016.
Article in English | MEDLINE | ID: mdl-25797944

ABSTRACT

OBJECTIVE: To evaluate the impact of contamination, or the presence of child maltreatment in a comparison condition, when estimating the broad, longitudinal effects of child maltreatment on female health at the transition to adulthood. METHODS: The Female Adolescent Development Study (N = 514; age range: 14-19 years) used a prospective cohort design to examine the effects of substantiated child maltreatment on teenage births, obesity, major depression, and past-month cigarette use. Contamination was controlled via a multimethod strategy that used both adolescent self-report and Child Protective Services records to remove cases of child maltreatment from the comparison condition. RESULTS: Substantiated child maltreatment significantly predicted each outcome, relative risks = 1.47-2.95, 95% confidence intervals: 1.03-7.06, with increases in corresponding effect size magnitudes, only when contamination was controlled using the multimethod strategy. CONCLUSIONS: Contamination truncates risk estimates of child maltreatment and controlling it can strengthen overall conclusions about the effects of child maltreatment on female health.


Subject(s)
Adolescent Health , Child Abuse/psychology , Depressive Disorder, Major/etiology , Obesity/etiology , Pregnancy in Adolescence/psychology , Smoking/psychology , Adolescent , Adolescent Development , Case-Control Studies , Depressive Disorder, Major/epidemiology , Female , Follow-Up Studies , Humans , Obesity/epidemiology , Pregnancy , Pregnancy in Adolescence/statistics & numerical data , Prospective Studies , Risk , Risk Factors , Self Report , Smoking/epidemiology , United States , Young Adult
12.
Dev Psychopathol ; 27(4 Pt 2): 1503-14, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26535940

ABSTRACT

Major depressive disorder (MDD) is a prevalent psychiatric condition in the child maltreatment population. However, not all children who have been maltreated will develop MDD or MDD symptoms, suggesting the presence of unique risk pathways that explain how certain children develop MDD symptoms when others do not. The current study tested several candidate risk pathways to MDD symptoms following child maltreatment: neuroendocrine, autonomic, affective, and emotion regulation. Female adolescents (N = 110; age range = 14-19) were recruited into a substantiated child maltreatment or comparison condition and completed a laboratory stressor, saliva samples, and measures of emotion regulation, negative affect, and MDD symptoms. MDD symptoms were reassessed 18 months later. Mediational modeling revealed that emotion regulation was the only significant indirect effect of the relationship between child maltreatment and subsequent MDD symptoms, demonstrating that children exposed to maltreatment had greater difficulties managing affective states that in turn led to more severe MDD symptoms. These results highlight the importance of emotion dysregulation as a central risk pathway to MDD following child maltreatment. Areas of future research and implications for optimizing prevention and clinical intervention through the direct targeting of transdiagnostic risk pathways are discussed.


Subject(s)
Child Abuse/psychology , Depressive Disorder, Major/etiology , Emotions/physiology , Self-Control/psychology , Adolescent , Adult , Depressive Disorder, Major/metabolism , Female , Humans , Hydrocortisone/metabolism , Risk , Young Adult , alpha-Amylases/metabolism
13.
J Acoust Soc Am ; 138(3): 1418-27, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26428780

ABSTRACT

When listeners know the content of the message they are about to hear, the clarity of distorted or partially masked speech increases dramatically. The current experiments investigated this priming phenomenon quantitatively using a same-different task where a typed caption and auditory message either matched exactly or differed by one key word. Four conditions were tested with groups of normal-hearing listeners: (a) natural speech presented in two-talker babble in a non-spatial configuration, (b) same as (a) but with the masker time reversed, (c) same as (a) but with target-masker spatial separation, and (d) vocoded sentences presented in speech-spectrum noise. The primary manipulation was the timing of the caption relative to the auditory message, which varied in 20 steps with a resolution of 200 ms. Across all four conditions, optimal performance was achieved when the initiation of the text preceded the acoustic speech signal by at least 400 ms, driven mostly by a low number of "different" responses to Same stimuli. Performance was slightly poorer with simultaneous delivery and much poorer when the auditory signal preceded the caption. Because priming may be used to facilitate perceptual learning, identifying optimal temporal conditions for priming could help determine the best conditions for auditory training.


Subject(s)
Hearing/physiology , Perceptual Masking/physiology , Speech Perception/physiology , Acoustic Stimulation , Adult , Cues , Female , Humans , Male , ROC Curve , Speech Discrimination Tests , Young Adult
14.
J Youth Adolesc ; 44(10): 1841-53, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26307243

ABSTRACT

Although peer pressure can influence adolescents' alcohol use, individual susceptibility to these pressures varies across individuals. The dopamine receptor D4 gene (DRD4) is a potential candidate gene that may influence adolescents' susceptibility to their peer environment due to the role dopamine plays in reward sensation during social interaction. We hypothesized that DRD4 genotype status would moderate the impact of 7th-grade antisocial peer pressure on 12th-grade lifetime alcohol use (n = 414; 58.7% female; 92.8% White). The results revealed significant main effects for antisocial peer pressure, but no main effects for DRD4 genotype on lifetime alcohol use. Adolescent DRD4 genotype moderated the association between peer pressure and lifetime alcohol use. For individuals who carried at least one copy of the DRD4 7-repeat allele (7+), antisocial peer pressure was associated with increased lifetime alcohol use. These findings indicate that genetic sensitivity to peer pressure confers increased alcohol use in late adolescence.


Subject(s)
Adolescent Behavior/psychology , Alcohol Drinking/psychology , Gene-Environment Interaction , Individuality , Receptors, Dopamine D4 , Adolescent , Alcohol Drinking/genetics , Female , Friends/psychology , Genetic Predisposition to Disease , Humans , Male , Peer Group , Risk Factors
15.
J Acoust Soc Am ; 135(5): 2923-30, 2014 May.
Article in English | MEDLINE | ID: mdl-24815272

ABSTRACT

Three effects that show a temporal asymmetry in the influence of interaural cues were studied through the addition of masking noise: (1) The transient precedence effect-the perceptual dominance of a leading transient over a similar lagging transient; (2) the ongoing precedence effect-lead dominance with lead and lag components that extend in time; and (3) the onset capture effect-determination by an onset transient of the lateral position of an otherwise ambiguous extended trailing sound. These three effects were evoked with noise-burst stimuli and were compared in the presence of masking noise. Using a diotic noise masker, detection thresholds for stimuli with lead/lag interaural delays of 0/500 µs were compared to those with 500/0 µs delays. None of the three effects showed a masking difference between those conditions, suggesting that none of the effects is operative at masked threshold. A task requiring the discrimination between stimuli with 500/0 and 0/500 µs interaural delays was used to determine the threshold for each effect in noise. The results showed similar thresholds in noise (10-13 dB SL) for the transient and ongoing precedence effects, but a much higher threshold (33 dB SL) for onset capture of an ambiguous trailing sound.


Subject(s)
Auditory Threshold/physiology , Cues , Differential Threshold/physiology , Noise , Perceptual Masking/physiology , Sound Localization/physiology , Acoustic Stimulation , Adult , Female , Humans , Psychometrics , Space Perception/physiology , Time Perception/physiology , Young Adult
16.
J Acoust Soc Am ; 134(2): 1183-92, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23927117

ABSTRACT

Priming is demonstrated when prior information about the content of a distorted, filtered, or masked auditory message improves its clarity. The current experiment attempted to quantify aspects of priming by determining its effects on performance and bias in a lowpass-filter-cutoff frequency discrimination task. Nonsense sentences recorded by a female talker were sharply lowpass filtered at a nominal cutoff frequency (F) of 0.5 or 0.75 kHz or at a higher cutoff frequency (F + ΔF). The listeners' task was to determine which interval of a two-interval-forced-choice trial contained the nonsense sentence filtered with F + ΔF. On priming trials, the interval 1 sentence was displayed on a computer screen prior to the auditory portion of the trial. The prime markedly affected bias, increasing the number of correct and incorrect interval 1 responses but did not affect overall discrimination performance substantially. These findings were supported through a second experiment that required listeners to make confidence judgments. The paradigm has the potential to help quantify the limits of speech perception when uncertainty about the auditory message is removed.


Subject(s)
Discrimination, Psychological , Speech Perception , Acoustic Stimulation , Adult , Audiometry, Speech , Auditory Threshold , Female , Humans , Judgment , Male , Middle Aged , Psychoacoustics , Task Performance and Analysis , Young Adult
17.
Otol Neurotol ; 44(5): e273-e280, 2023 06 01.
Article in English | MEDLINE | ID: mdl-37167444

ABSTRACT

OBJECTIVE: To determine the relationship between hearing loss etiology, cochlear implant (CI) programming levels, and speech perception performance in a large clinical cohort of pediatric CI recipients. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary care hospitals. PATIENTS: A total of 136 pediatric CI recipients (218 ears) were included in this study. All patients had diagnoses of either enlarged vestibular aqueduct (EVA) or GJB2 (Connexin-26) mutation confirmed via radiographic data and/or genetic reports. All patients received audiologic care at either Boston Children's Hospital or Massachusetts Eye and Ear in Boston, MA, between the years 1999 and 2020. MAIN OUTCOME MEASURES: Electrode impedances and programming levels for each active electrode and speech perception scores were evaluated as a function of etiology (EVA or GJB2 mutation). RESULTS: Children with EVA had significantly higher impedances and programming levels (thresholds and upper stimulation levels) than the children with GJB2 mutation. Speech perception scores did not differ as a function of etiology in this sample; rather, they were positively correlated with duration of CI experience (time since implantation). CONCLUSIONS: Differences in electrode impedances and CI programming levels suggest that the electrode-neuron interface varies systematically as a function of hearing loss etiology in pediatric CI recipients with EVA and those with GJB2 mutation. Time with the CI was a better predictor of speech perception scores than etiology, suggesting that children can adapt to CI stimulation with experience.


Subject(s)
Cochlear Implantation , Cochlear Implants , Deafness , Hearing Loss, Sensorineural , Speech Perception , Vestibular Aqueduct , Child , Humans , Connexins/genetics , Deafness/genetics , Deafness/surgery , Hearing Loss, Sensorineural/surgery , Mutation , Retrospective Studies , Vestibular Aqueduct/surgery
18.
J Acoust Soc Am ; 132(4): 2514-23, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23039445

ABSTRACT

This study investigated the role of natural periodic temporal fine structure in helping listeners take advantage of temporal valleys in amplitude-modulated masking noise when listening to speech. Young normal-hearing participants listened to natural, whispered, and/or vocoded nonsense sentences in a variety of masking conditions. Whispering alters normal waveform temporal fine structure dramatically but, unlike vocoding, does not degrade spectral details created by vocal tract resonances. The improvement in intelligibility, or masking release, due to introducing 16-Hz square-wave amplitude modulations in an otherwise steady speech-spectrum noise was reduced substantially with vocoded sentences relative to natural speech, but was not reduced for whispered sentences. In contrast to natural speech, masking release for whispered sentences was observed even at positive signal-to-noise ratios. Whispered speech has a different short-term amplitude distribution relative to natural speech, and this appeared to explain the robust masking release for whispered speech at high signal-to-noise ratios. Recognition of whispered speech was not disproportionately affected by unpredictable modulations created by a speech-envelope modulated noise masker. Overall, the presence or absence of periodic temporal fine structure did not have a major influence on the degree of benefit obtained from imposing temporal fluctuations on a noise masker.


Subject(s)
Cues , Noise/adverse effects , Perceptual Masking , Speech Acoustics , Speech Intelligibility , Speech Perception , Acoustic Stimulation , Audiometry, Speech , Female , Humans , Loudness Perception , Time Factors , Young Adult
19.
Dev Psychol ; 57(3): 347-360, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33570984

ABSTRACT

Understanding the role of negative emotionality in the development of executive functioning (EF) and language skills can help identify developmental windows that may provide promising opportunities for intervention. In addition, because EF and language skills are, in part, genetically influenced, intergenerational transmission patterns are important to consider. The prospective parent-offspring adoption design used in this study provides a unique opportunity to examine the intergenerational transmission of EF and language skills. Participants were 561 children adopted around the time of birth. Accounting for birth mother EF and language contributions, we examined the role of child negative emotionality in toddlerhood (age 9 to 27 months) and childhood (age 4.5 to 7 years) on child EF and language skills in first grade (age 7 years). There was continuity in EF from age 27 months to 7 years, and in language ability from age 27 months to 7 years, with no cross-lagged effects between child EF and language ability. Negative emotionality at age 9 months predicted lower EF and lower language abilities at age 7 years, and growth in negative emotionality from age 4.5 to 7 years predicted lower child EF at age 7 years. Overall, findings suggested that lower negative emotionality at age 9 months was associated with higher toddler and child EF and language skills and that preventing growth in negative emotionality from age 4.5 to 7 years may lead to improvements in child EF. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Executive Function , Language , Child , Child Development , Child, Preschool , Female , Humans , Infant , Mothers , Prospective Studies
20.
Lang Speech Hear Serv Sch ; 51(1): 29-41, 2020 01 08.
Article in English | MEDLINE | ID: mdl-31913800

ABSTRACT

Purpose The purpose of this study was to measure auditory comprehension performance in school-aged children with unilateral hearing loss (UHL) and with normal hearing (NH) in quiet and in the presence of child-produced two-talker babble (TTB). Method Listeners were school-aged children (7-12 years) with permanent UHL (n = 25) or NH (n = 14). Comprehension of three short stories taken from the Test of Narrative Language (Gillam & Pearson, 2004) was measured in quiet and in the presence of TTB at two signal-to-noise ratios (SNRs): (a) +6 dB and (b) the individualized SNR required to achieve 50% sentence understanding in the presence of the same TTB masker in a prior study (Griffin, Poissant, & Freyman, 2019). Target/masker spatial configuration was 0°/±60° azimuth. Results As a group, subjects with UHL demonstrated auditory comprehension abilities in favorable listening environments (i.e., quiet, +6 dB SNR) that were statistically equivalent to the NH group. However, in the most challenging listening condition (individualized SNR), many subjects with UHL demonstrated poorer comprehension performance than their age-matched peers with NH. Comprehension abilities were not associated with degree of UHL, unaided speech intelligibility index at 65 dB SPL in the impaired ear, side of UHL, or sex. Conclusions As a group, children with UHL demonstrated deficits in auditory comprehension compared to age-matched peers with NH in challenging listening environments. Findings highlight the importance of ensuring good SNRs for children with UHL.


Subject(s)
Auditory Perception/physiology , Comprehension , Hearing Loss, Unilateral/diagnostic imaging , Speech Intelligibility/physiology , Speech Perception/physiology , Child , Female , Hearing , Humans , Language , Male , Signal-To-Noise Ratio
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