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1.

Adjunctive Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults.

Donovan, Joseph; Bang, Nguyen D; Imran, Darma; Nghia, Ho D T; Burhan, Erlina; Huong, Dau T T; Hiep, Nguyen T T; Ngoc, Lam H B; Thanh, Dang V; Thanh, Nguyen T; Wardhani, Anna L S; Maharani, Kartika; Gasmara, Cakra P; Hanh, Nguyen H H; Oanh, Pham K N; Estiasari, Riwanti; Thu, Do D A; Kusumaningrum, Ardiana; Dung, Le T; Giang, Do C; Ha, Dang T M; Lan, Nguyen H; Chau, Nguyen V V; Nguyet, Nguyen T M; Geskus, Ronald B; Thuong, Nguyen T T; Kestelyn, Evelyne; Hamers, Raph L; Phu, Nguyen H; Thwaites, Guy E.

N Engl J Med ; 389(15): 1357-1367, 2023 Oct 12.

Article in English | MEDLINE | ID: mdl-37819954

2.

Clinical presentation, management, and outcome of suspected central nervous system infections in Indonesia: a prospective cohort study.

Maharani, Kartika; Dian, Sofiati; Ganiem, Ahmad Rizal; Imran, Darma; Estiasari, Riwanti; Ardiansyah, Edwin; Andini, Putri Widya; Kristina, Fransisca; Pangeran, David; Chaidir, Lidya; Alisjahbana, Bachti; Rukmana, Andriansjah; Kusumaningrum, Ardiana; Adawiyah, Robiatul; Subekti, Decy; Yunihastuti, Evy; Yunus, Reyhan Eddy; Waslia, Lia; van Ingen, Jakko; van Laarhoven, Arjan; Hamers, Raph L; van Crevel, Reinout.

Infection ; 52(2): 583-595, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38315377

3.

Understanding the Potential Impact of Different Drug Properties on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission and Disease Burden: A Modelling Analysis.

Whittaker, Charles; Watson, Oliver J; Alvarez-Moreno, Carlos; Angkasekwinai, Nasikarn; Boonyasiri, Adhiratha; Carlos Triana, Luis; Chanda, Duncan; Charoenpong, Lantharita; Chayakulkeeree, Methee; Cooke, Graham S; Croda, Julio; Cucunubá, Zulma M; Djaafara, Bimandra A; Estofolete, Cassia F; Grillet, Maria Eugenia; Faria, Nuno R; Figueiredo Costa, Silvia; Forero-Peña, David A; Gibb, Diana M; Gordon, Anthony C; Hamers, Raph L; Hamlet, Arran; Irawany, Vera; Jitmuang, Anupop; Keurueangkul, Nukool; Kimani, Teresia Njoki; Lampo, Margarita; Levin, Anna S; Lopardo, Gustavo; Mustafa, Rima; Nayagam, Shevanthi; Ngamprasertchai, Thundon; Njeri, Ng'ang'a Irene Hannah; Nogueira, Mauricio L; Ortiz-Prado, Esteban; Perroud, Mauricio W; Phillips, Andrew N; Promsin, Panuwat; Qavi, Ambar; Rodger, Alison J; Sabino, Ester C; Sangkaew, Sorawat; Sari, Djayanti; Sirijatuphat, Rujipas; Sposito, Andrei C; Srisangthong, Pratthana; Thompson, Hayley A; Udwadia, Zarir; Valderrama-Beltrán, Sandra; Winskill, Peter.

Clin Infect Dis ; 75(1): e224-e233, 2022 08 24.

Article in English | MEDLINE | ID: mdl-34549260

4.

Plasma Inflammatory Biomarkers Predict CD4+ T-cell Recovery and Viral Rebound in HIV-1 Infected Africans on Suppressive Antiretroviral Therapy.

Kroeze, Stefanie; Rossouw, Theresa M; Steel, Helen C; Wit, Ferdinand W; Kityo, Cissy M; Siwale, Margaret; Akanmu, Sulaimon; Mandaliya, Kishor; De Jager, Marleen; Ondoa, Pascale; Reiss, Peter; Rinke De Wit, Tobias F; Kootstra, Neeltje A; Hamers, Raph L.

J Infect Dis ; 224(4): 673-678, 2021 08 16.

Article in English | MEDLINE | ID: mdl-33373447

5.

2021 update to HIV-TRePS: a highly flexible and accurate system for the prediction of treatment response from incomplete baseline information in different healthcare settings.

Revell, Andrew D; Wang, Dechao; Perez-Elias, Maria-Jesus; Wood, Robin; Cogill, Dolphina; Tempelman, Hugo; Hamers, Raph L; Reiss, Peter; van Sighem, Ard; Rehm, Catherine A; Agan, Brian; Alvarez-Uria, Gerardo; Montaner, Julio S G; Lane, H Clifford; Larder, Brendan A.

J Antimicrob Chemother ; 76(7): 1898-1906, 2021 06 18.

Article in English | MEDLINE | ID: mdl-33792714

6.

Distinct rates and patterns of spread of the major HIV-1 subtypes in Central and East Africa.

Faria, Nuno R; Vidal, Nicole; Lourenco, José; Raghwani, Jayna; Sigaloff, Kim C E; Tatem, Andy J; van de Vijver, David A M; Pineda-Peña, Andrea-Clemencia; Rose, Rebecca; Wallis, Carole L; Ahuka-Mundeke, Steve; Muyembe-Tamfum, Jean-Jacques; Muwonga, Jérémie; Suchard, Marc A; Rinke de Wit, Tobias F; Hamers, Raph L; Ndembi, Nicaise; Baele, Guy; Peeters, Martine; Pybus, Oliver G; Lemey, Philippe; Dellicour, Simon.

PLoS Pathog ; 15(12): e1007976, 2019 12.

Article in English | MEDLINE | ID: mdl-31809523

7.

Low-Abundance Drug-Resistant HIV-1 Variants in Antiretroviral Drug-Naive Individuals: A Systematic Review of Detection Methods, Prevalence, and Clinical Impact.

Mbunkah, Herbert A; Bertagnolio, Silvia; Hamers, Raph L; Hunt, Gillian; Inzaule, Seth; Rinke De Wit, Tobias F; Paredes, Roger; Parkin, Neil T; Jordan, Michael R; Metzner, Karin J.

J Infect Dis ; 221(10): 1584-1597, 2020 04 27.

Article in English | MEDLINE | ID: mdl-31809534

8.

Plasma Biomarkers of Human Immunodeficiency Virus-Related Systemic Inflammation and Immune Activation in Sub-Saharan Africa Before and During Suppressive Antiretroviral Therapy.

Kroeze, Stefanie; Wit, Ferdinand W; Rossouw, Theresa M; Steel, Helen C; Kityo, Cissy M; Siwale, Margaret; Akanmu, Sulaimon; Mandaliya, Kishor; de Jager, Marleen; Ondoa, Pascale; Reiss, Peter; Rinke de Wit, Tobias F; Kootstra, Neeltje; Hamers, Raph L.

J Infect Dis ; 220(6): 1029-1033, 2019 08 09.

Article in English | MEDLINE | ID: mdl-31086991

9.

Primary resistance to integrase strand transfer inhibitors in patients infected with diverse HIV-1 subtypes in sub-Saharan Africa.

Inzaule, Seth C; Hamers, Raph L; Noguera-Julian, Marc; Casadellà, Maria; Parera, Mariona; Rinke de Wit, Tobias F; Paredes, Roger.

J Antimicrob Chemother ; 73(5): 1167-1172, 2018 05 01.

Article in English | MEDLINE | ID: mdl-29462322

10.

2018 update to the HIV-TRePS system: the development of new computational models to predict HIV treatment outcomes, with or without a genotype, with enhanced usability for low-income settings.

Revell, Andrew D; Wang, Dechao; Perez-Elias, Maria-Jesus; Wood, Robin; Cogill, Dolphina; Tempelman, Hugo; Hamers, Raph L; Reiss, Peter; van Sighem, Ard I; Rehm, Catherine A; Pozniak, Anton; Montaner, Julio S G; Lane, H Clifford; Larder, Brendan A.

J Antimicrob Chemother ; 73(8): 2186-2196, 2018 08 01.

Article in English | MEDLINE | ID: mdl-29889249

11.

Protease Inhibitor Resistance in the First 3 Years of Second-Line Antiretroviral Therapy for HIV-1 in Sub-Saharan Africa.

Boender, T Sonia; Hamers, Raph L; Ondoa, Pascale; Wellington, Maureen; Chimbetete, Cleophas; Siwale, Margaret; Labib Maksimos, Eman E F; Balinda, Sheila N; Kityo, Cissy M; Adeyemo, Titilope A; Akanmu, Alani Sulaimon; Mandaliya, Kishor; Botes, Mariette E; Stevens, Wendy; Rinke de Wit, Tobias F; Sigaloff, Kim C E.

J Infect Dis ; 214(6): 873-83, 2016 09 15.

Article in English | MEDLINE | ID: mdl-27402780

12.

HIV Drug Resistance.

Inzaule, Seth C; Rinke de Wit, Tobias F; Hamers, Raph L.

N Engl J Med ; 378(9): 873-4, 2018 03 01.

Article in English | MEDLINE | ID: mdl-29504387

13.

Prevalence and dynamics of the K65R drug resistance mutation in HIV-1-infected infants exposed to maternal therapy with lamivudine, zidovudine and either nevirapine or nelfinavir in breast milk.

Inzaule, Seth C; Weidle, Paul J; Yang, Chunfu; Ndiege, Kenneth; Hamers, Raph L; Rinke de Wit, Tobias F; Thomas, Timothy; Zeh, Clement.

J Antimicrob Chemother ; 71(6): 1619-26, 2016 06.

Article in English | MEDLINE | ID: mdl-26953333

14.

An update to the HIV-TRePS system: the development and evaluation of new global and local computational models to predict HIV treatment outcomes, with or without a genotype.

Revell, Andrew D; Wang, Dechao; Wood, Robin; Morrow, Carl; Tempelman, Hugo; Hamers, Raph L; Reiss, Peter; van Sighem, Ard I; Nelson, Mark; Montaner, Julio S G; Lane, H Clifford; Larder, Brendan A.

J Antimicrob Chemother ; 71(10): 2928-37, 2016 10.

Article in English | MEDLINE | ID: mdl-27330070

15.

Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa.

Boender, T Sonia; Kityo, Cissy M; Boerma, Ragna S; Hamers, Raph L; Ondoa, Pascale; Wellington, Maureen; Siwale, Margaret; Nankya, Immaculate; Kaudha, Elizabeth; Akanmu, Alani Sulaimon; Botes, Mariette E; Steegen, Kim; Calis, Job C J; Rinke de Wit, Tobias F; Sigaloff, Kim C E.

J Antimicrob Chemother ; 71(10): 2918-27, 2016 10.

Article in English | MEDLINE | ID: mdl-27342546

16.

Pretreatment HIV drug resistance increases regimen switches in sub-Saharan Africa.

Boender, T Sonia; Hoenderboom, Bernice M; Sigaloff, Kim C E; Hamers, Raph L; Wellington, Maureen; Shamu, Tinei; Siwale, Margaret; Labib Maksimos, Eman E F; Nankya, Immaculate; Kityo, Cissy M; Adeyemo, Titilope A; Akanmu, Alani Sulaimon; Mandaliya, Kishor; Botes, Mariette E; Ondoa, Pascale; Rinke de Wit, Tobias F.

Clin Infect Dis ; 61(11): 1749-58, 2015 Dec 01.

Article in English | MEDLINE | ID: mdl-26240203

17.

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis.

Rhee, Soo-Yon; Blanco, Jose Luis; Jordan, Michael R; Taylor, Jonathan; Lemey, Philippe; Varghese, Vici; Hamers, Raph L; Bertagnolio, Silvia; Rinke de Wit, Tobias F; Aghokeng, Avelin F; Albert, Jan; Avi, Radko; Avila-Rios, Santiago; Bessong, Pascal O; Brooks, James I; Boucher, Charles A B; Brumme, Zabrina L; Busch, Michael P; Bussmann, Hermann; Chaix, Marie-Laure; Chin, Bum Sik; D'Aquin, Toni T; De Gascun, Cillian F; Derache, Anne; Descamps, Diane; Deshpande, Alaka K; Djoko, Cyrille F; Eshleman, Susan H; Fleury, Herve; Frange, Pierre; Fujisaki, Seiichiro; Harrigan, P Richard; Hattori, Junko; Holguin, Africa; Hunt, Gillian M; Ichimura, Hiroshi; Kaleebu, Pontiano; Katzenstein, David; Kiertiburanakul, Sasisopin; Kim, Jerome H; Kim, Sung Soon; Li, Yanpeng; Lutsar, Irja; Morris, Lynn; Ndembi, Nicaise; Ng, Kee Peng; Paranjape, Ramesh S; Peeters, Martine; Poljak, Mario; Price, Matt A.

PLoS Med ; 12(4): e1001810, 2015 Apr.

Article in English | MEDLINE | ID: mdl-25849352

18.

Does Tenofovir-containing First-line Antiretroviral Therapy Mitigate the Impact of Pretreatment Non-nucleoside Reverse Transcriptase Inhibitor Drug Resistance?

Inzaule, Seth C; Rinke de Wit, Tobias F; Hamers, Raph L.

Clin Infect Dis ; 68(12): 2158-2160, 2019 05 30.

Article in English | MEDLINE | ID: mdl-30561519

19.

Benznidazole for Chronic Chagas' Cardiomyopathy.

Hamers, Raph L; van Gool, Tom; Goorhuis, Abraham.

N Engl J Med ; 374(2): 188, 2016 01 14.

Article in English | MEDLINE | ID: mdl-26760093

20.

Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine.

Tang, Michele W; Rhee, Soo-Yon; Bertagnolio, Silvia; Ford, Nathan; Holmes, Susan; Sigaloff, Kim C; Hamers, Raph L; de Wit, Tobias F Rinke; Fleury, Herve J; Kanki, Phyllis J; Ruxrungtham, Kiat; Hawkins, Claudia A; Wallis, Carole L; Stevens, Wendy; van Zyl, Gert U; Manosuthi, Weerawat; Hosseinipour, Mina C; Ngo-Giang-Huong, Nicole; Belec, Laurent; Peeters, Martine; Aghokeng, Avelin; Bunupuradah, Torsak; Burda, Sherri; Cane, Patricia; Cappelli, Giulia; Charpentier, Charlotte; Dagnra, Anoumou Y; Deshpande, Alaka K; El-Katib, Ziad; Eshleman, Susan H; Fokam, Joseph; Gody, Jean-Chrysostome; Katzenstein, David; Koyalta, Donato D; Kumwenda, Johnstone J; Lallemant, Marc; Lynen, Lutgarde; Marconi, Vincent C; Margot, Nicolas A; Moussa, Sandrine; Ndung'u, Thumbi; Nyambi, Phillipe N; Orrell, Catherine; Schapiro, Jonathan M; Schuurman, Rob; Sirivichayakul, Sunee; Smith, Davey; Zolfo, Maria; Jordan, Michael R; Shafer, Robert W.

J Infect Dis ; 207 Suppl 2: S70-7, 2013 Jun 15.

Article in English | MEDLINE | ID: mdl-23687292

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