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1.

Targeted nonviral delivery of genome editors in vivo.

Tsuchida, Connor A; Wasko, Kevin M; Hamilton, Jennifer R; Doudna, Jennifer A.

Proc Natl Acad Sci U S A ; 121(11): e2307796121, 2024 Mar 12.

Article in English | MEDLINE | ID: mdl-38437567

2.

CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells.

Lin-Shiao, Enrique; Pfeifer, Wolfgang G; Shy, Brian R; Saffari Doost, Mohammad; Chen, Evelyn; Vykunta, Vivasvan S; Hamilton, Jennifer R; Stahl, Elizabeth C; Lopez, Diana M; Sandoval Espinoza, Cindy R; Deyanov, Alexander E; Lew, Rachel J; Poirer, Michael G; Marson, Alexander; Castro, Carlos E; Doudna, Jennifer A.

Nucleic Acids Res ; 50(3): 1256-1268, 2022 02 22.

Article in English | MEDLINE | ID: mdl-35104875

3.

Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.

Hamilton, Jennifer R; Sachs, David; Lim, Jean K; Langlois, Ryan A; Palese, Peter; Heaton, Nicholas S.

Proc Natl Acad Sci U S A ; 113(14): 3861-6, 2016 Apr 05.

Article in English | MEDLINE | ID: mdl-27001854

4.

NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes.

Vliet-Gregg, Portia A; Hamilton, Jennifer R; Katzenellenbogen, Rachel A.

J Virol ; 87(24): 13741-50, 2013 Dec.

Article in English | MEDLINE | ID: mdl-24109236

5.

In vivo human T cell engineering with enveloped delivery vehicles.

Hamilton, Jennifer R; Chen, Evelyn; Perez, Barbara S; Sandoval Espinoza, Cindy R; Kang, Min Hyung; Trinidad, Marena; Ngo, Wayne; Doudna, Jennifer A.

Nat Biotechnol ; 2024 Jan 11.

Article in English | MEDLINE | ID: mdl-38212493

6.

Distinct gene programs underpinning disease tolerance and resistance in influenza virus infection.

Cohn, Ofir; Yankovitz, Gal; Peshes-Yaloz, Naama; Steuerman, Yael; Frishberg, Amit; Brandes, Rachel; Mandelboim, Michal; Hamilton, Jennifer R; Hagai, Tzachi; Amit, Ido; Netea, Mihai G; Hacohen, Nir; Iraqi, Fuad A; Bacharach, Eran; Gat-Viks, Irit.

Cell Syst ; 13(12): 1002-1015.e9, 2022 12 21.

Article in English | MEDLINE | ID: mdl-36516834

7.

Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering.

Hamilton, Jennifer R; Tsuchida, Connor A; Nguyen, David N; Shy, Brian R; McGarrigle, E Riley; Sandoval Espinoza, Cindy R; Carr, Daniel; Blaeschke, Franziska; Marson, Alexander; Doudna, Jennifer A.

Cell Rep ; 35(9): 109207, 2021 06 01.

Article in English | MEDLINE | ID: mdl-34077734

8.

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

Hamilton, Jennifer R; Stahl, Elizabeth C; Tsuchida, Connor A; Lin-Shiao, Enrique; Tsui, C Kimberly; Pestal, Kathleen; Gildea, Holly K; Witkowsky, Lea B; Moehle, Erica A; McDevitt, Shana L; McElroy, Matthew; Keller, Amanda; Sylvain, Iman; Hirsh, Ariana; Ciling, Alison; Ehrenberg, Alexander J; Ringeisen, Bradley R; Huberty, Garth; Urnov, Fyodor D; Giannikopoulos, Petros; Doudna, Jennifer A.

medRxiv ; 2021 Jan 29.

Article in English | MEDLINE | ID: mdl-33532798

9.

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

Hamilton, Jennifer R; Stahl, Elizabeth C; Tsuchida, Connor A; Lin-Shiao, Enrique; Tsui, C Kimberly; Pestal, Kathleen; Gildea, Holly K; Witkowsky, Lea B; Moehle, Erica A; McDevitt, Shana L; McElroy, Matthew; Keller, Amanda; Sylvain, Iman; Hirsh, Ariana; Ciling, Alison; Ehrenberg, Alexander J; Ringeisen, Bradley R; Huberty, Garth; Urnov, Fyodor D; Giannikopoulos, Petros; Doudna, Jennifer A.

PLoS One ; 16(8): e0255690, 2021.

Article in English | MEDLINE | ID: mdl-34351984

10.

LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.

Stahl, Elizabeth C; Gopez, Allan R; Tsuchida, Connor A; Fan, Vinson B; Moehle, Erica A; Witkowsky, Lea B; Hamilton, Jennifer R; Lin-Shiao, Enrique; McElroy, Matthew; McDevitt, Shana L; Ciling, Alison; Tsui, C Kimberly; Pestal, Kathleen; Gildea, Holly K; Keller, Amanda; Sylvain, Iman A; Williams, Clara; Hirsh, Ariana; Ehrenberg, Alexander J; Kantor, Rose; Metzger, Matthew; Nelson, Kara L; Urnov, Fyodor D; Ringeisen, Bradley R; Giannikopoulos, Petros; Doudna, Jennifer A.

PLoS One ; 16(11): e0258263, 2021.

Article in English | MEDLINE | ID: mdl-34758033

11.

Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus.

Ehrenberg, Alexander J; Moehle, Erica A; Brook, Cara E; Doudna Cate, Andrew H; Witkowsky, Lea B; Sachdeva, Rohan; Hirsh, Ariana; Barry, Kerrie; Hamilton, Jennifer R; Lin-Shiao, Enrique; McDevitt, Shana; Valentin-Alvarado, Luis; Letourneau, Kaitlyn N; Hunter, Lauren; Keller, Amanda; Pestal, Kathleen; Frankino, Phillip A; Murley, Andrew; Nandakumar, Divya; Stahl, Elizabeth C; Tsuchida, Connor A; Gildea, Holly K; Murdock, Andrew G; Hochstrasser, Megan L; O'Brien, Elizabeth; Ciling, Alison; Tsitsiklis, Alexandra; Worden, Kurtresha; Dugast-Darzacq, Claire; Hays, Stephanie G; Barber, Colin C; McGarrigle, Riley; Lam, Emily K; Ensminger, David C; Bardet, Lucie; Sherry, Carolyn; Harte, Anna; Nicolette, Guy; Giannikopoulos, Petros; Hockemeyer, Dirk; Petersen, Maya; Urnov, Fyodor D; Ringeisen, Bradley R; Boots, Mike; Doudna, Jennifer A.

PLoS One ; 16(5): e0251296, 2021.

Article in English | MEDLINE | ID: mdl-34038425

12.

Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice.

Bliss, Carly M; Parsons, Andrea J; Nachbagauer, Raffael; Hamilton, Jennifer R; Cappuccini, Federica; Ulaszewska, Marta; Webber, Jason P; Clayton, Aled; Hill, Adrian V S; Coughlan, Lynda.

Mol Ther Methods Clin Dev ; 16: 108-125, 2020 Mar 13.

Article in English | MEDLINE | ID: mdl-31934599

13.

IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2.

Stahl, Elizabeth C; Tsuchida, Connor A; Hamilton, Jennifer R; Lin-Shiao, Enrique; McDevitt, Shana L; Moehle, Erica A; Witkowsky, Lea B; Tsui, C Kimberly; Pestal, Kathleen; Gildea, Holly K; McElroy, Matthew; Keller, Amanda; Sylvain, Iman; Williams, Clara; Hirsh, Ariana; Ciling, Alison; Ehrenberg, Alexander J; Urnov, Fyodor D; Ringeisen, Bradley R; Giannikopoulos, Petros; Doudna, Jennifer A.

medRxiv ; 2020 Dec 11.

Article in English | MEDLINE | ID: mdl-33330883

14.

DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection.

Chambers, Benjamin S; Heaton, Brook E; Rausch, Keiko; Dumm, Rebekah E; Hamilton, Jennifer R; Cherry, Sara; Heaton, Nicholas S.

Nat Microbiol ; 4(11): 1964-1977, 2019 11.

Article in English | MEDLINE | ID: mdl-31358986

15.

A Recombinant Antibody-Expressing Influenza Virus Delays Tumor Growth in a Mouse Model.

Hamilton, Jennifer R; Vijayakumar, Gayathri; Palese, Peter.

Cell Rep ; 22(1): 1-7, 2018 01 02.

Article in English | MEDLINE | ID: mdl-29298413

16.

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice.

He, Wenqian; Chen, Chi-Jene; Mullarkey, Caitlin E; Hamilton, Jennifer R; Wong, Christine K; Leon, Paul E; Uccellini, Melissa B; Chromikova, Veronika; Henry, Carole; Hoffman, Kevin W; Lim, Jean K; Wilson, Patrick C; Miller, Matthew S; Krammer, Florian; Palese, Peter; Tan, Gene S.

Nat Commun ; 8(1): 846, 2017 10 10.

Article in English | MEDLINE | ID: mdl-29018261

17.

Knocking out barriers to engineered cell activity.

Hamilton, Jennifer R; Doudna, Jennifer A.

Science ; 367(6481): 976-977, 2020 02 28.

Article in English | MEDLINE | ID: mdl-32029685

18.

Human papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrest.

Vliet-Gregg, Portia A; Hamilton, Jennifer R; Katzenellenbogen, Rachel A.

Virology ; 478: 50-60, 2015 Apr.

Article in English | MEDLINE | ID: mdl-25723053

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Targeted nonviral delivery of genome editors in vivo.

CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells.

Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.

NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes.

In vivo human T cell engineering with enveloped delivery vehicles.

Distinct gene programs underpinning disease tolerance and resistance in influenza virus infection.

Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering.

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.

Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus.

Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice.

IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2.

DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection.

A Recombinant Antibody-Expressing Influenza Virus Delays Tumor Growth in a Mouse Model.

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice.

Knocking out barriers to engineered cell activity.

Human papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrest.