Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters

Database
Language
Affiliation country
Publication year range
1.
J Infect Dis ; 224(12 Suppl 2): S759-S763, 2021 12 20.
Article in English | MEDLINE | ID: mdl-34586391

ABSTRACT

The burden of Salmonella enterica serotype Typhi (S. Typhi) shedding in stool and its contribution to transmission in endemic settings is unknown. During passive surveillance S. Typhi shedding was seen during convalescence in 332 bacteremic patient with typhoid, although none persisted at 1-year follow-up. Anti-virulence capsule (Vi)-immunoglobulin (Ig) G titers were measured in age-stratified cohort of serosurveillance participants. Systematic stool sampling of 303 participants with high anti-Vi-IgG titers identified 1 asymptomatic carrier with shedding. These findings suggest that ongoing S. Typhi transmission in this setting is more likely to occur from acute convalescent cases, although better approaches are needed to identify true chronic carriers in the community to enable typhoid elimination.


Subject(s)
Carrier State , Feces/microbiology , Salmonella typhi/isolation & purification , Typhoid Fever/diagnosis , Typhoid Fever/transmission , Adolescent , Adult , Bacterial Shedding , Child , Child, Preschool , Endemic Diseases , Humans , Infant , Middle Aged , Seroepidemiologic Studies , Typhoid Fever/epidemiology , Urban Population , Virulence , Young Adult
SELECTION OF CITATIONS
SEARCH DETAIL